transforming glycoscience

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Transforming Glycoscience

Author : National Research Council
ISBN : 9780309260831
Genre : Science
File Size : 34. 83 MB
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A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans--also known as carbohydrates, saccharides, or simply as sugars--play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.

Gas Phase Ir Spectroscopy And Structure Of Biological Molecules

Author : Anouk M. Rijs
ISBN : 9783319192048
Genre : Science
File Size : 36. 64 MB
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The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students.

Glycobiology Of The Nervous System

Author : Robert K. Yu
ISBN : 9781493911547
Genre : Medical
File Size : 40. 59 MB
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A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.

Experimental Glycoscience

Author : Naoyuki Taniguchi
ISBN : 4431779221
Genre : Science
File Size : 83. 64 MB
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The aim of this book is to provide experimental protocols covering many aspects of glycobiology, glycotechnology, and chemistry: biochemistry, molecular and cellular biology, genetics, physiology, and medicine. The protocols are all self-contained descriptions of the equipment and reagents needed, followed by details of the experimental procedure. In the post-genomic era, glycobiology is coming of age because more than half of proteins are glycosylated and the importance of sugar chains in various fields of life science research cannot be disregarded. Many scientists had not entered this area because glycobiology and glycoscience used to be considered difficult fields. This book, therefore, is presented much like a cookbook which can help scientists in fields other than glycobiology and glycoscience carry out research more easily.

Click Chemistry In Glycoscience

Author : Zbigniew J. Witczak
ISBN : 9781118526897
Genre : Science
File Size : 24. 46 MB
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Lays the foundation for new methods and applications ofcarbohydrate click chemistry Introduced by K. Barry Sharpless of The Scripps ResearchInstitute in 2001, click chemistry mimics nature, givingresearchers the tools needed to generate new substances quickly andreliably by joining small units together. With contributions frommore than thirty pioneering researchers in the field, this textexplores the many promising applications of click chemistry inglycoscience. Readers will learn both the basic concepts ofcarbohydrate click chemistry as well as its many biomedicalapplications, including synthetic antigens, analogs of cell-surfacereceptors, immobilized enzymes, targeted drug delivery systems, andmultivalent cancer vaccines. Click Chemistry in Glycoscience examines a broad range ofmethodologies and strategies that have emerged from this rapidlyevolving field. Each chapter describes new approaches, ideas,consequences, and applications resulting from the introduction ofclick processes. Divided into four sections, the book covers: Click chemistry strategies and decoupling Thio-click chemistry of carbohydrates Carbohydrate click chemistry for novel synthetic targets Carbohydrate click chemistry in biomedical sciences Thoroughly researched, the book reflects the most recentfindings published in the literature. Diagrams and figuresthroughout the book enable readers to more easily grasp complexconcepts and reaction processes. At the end of each chapter,references lead to the primary literature for further investigationof individual topics. The application of click chemistry to carbohydrates hastremendous implications for research. With this book as theirguide, researchers have a solid foundation from which they candevelop new methods and applications of carbohydrate clickchemistry, including new carbohydrate-based therapeutics.


Author : Arnold E. Stütz
ISBN : 9783540444220
Genre : Technology & Engineering
File Size : 72. 26 MB
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This series presents critical reviews of the present position and future trends in modern chemical research. The short and concise reports on chemistry, each written by the world’s renowned experts, are still valid and useful after 5 or 10 years.

Glycoscience Chemistry And Chemical Biology I Iii

Author : Bertram O. Fraser-Reid
ISBN : 354067764X
Genre : Science
File Size : 86. 9 MB
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Glycostructures play a highly diverse and crucial role in a myriad of organisms and systems in biology, physiology, medicine, and bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and chemistry behind them. In this set the editors present up-to-date information on glycostructures, their chemistry and chemical biology, in the form of a comprehensive survey. The text is accompanied by over 2000 figures, chemical structures and reaction schemes and more than 9000 references. The accompanying CD-ROM enables, besides text searches, searches for structures, schemes, and other information.

Introducing Smart Sugars

Author : J. C. Spencer
ISBN : 1481933183
Genre : Medical
File Size : 43. 64 MB
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The purpose of Introducing Smart Sugars is to provide a starting point for all people to learn about the imminent paradigm shift in medicine and healthcare. Super Sugars are evidence-based and the results are in the irrefutable facts. The emerging data from ongoing research are nothing short of amazing.The future of medicine and healthcare is Glycoscience. Undeniably, scientists agree that the explosive technological advances in Glycoscience will transform medicine and healthcare.Glycoscience has the potential to dramatically reduce health care costs.Glycoscience is rapidly becoming a part of mainstream medicine and was declared by Massachusetts Institute of Technology (MIT) as“ONE OF THE 10 EMERGING TECHNOLOGIESTHAT WILL CHANGE THE WORLD.”Working together, The National Institutes of Health (NIH), the Food and Drug Administration (FDA), the National Science Foundation (NSF), the National Research Council, the National Academy of Sciences, the Howard Hughes Medical Institute, and the U.S. Department of Energy (DOE), formed a committee to evaluate the importance, impact, and future of Glycoscience. The group was charged to “articulate a unified vision for the field on Glycoscience and Glycomics” and to “develop a roadmap with concrete research goals to significantly advance the field.” We will report on the committee and keep our readers informed with an easy to understand format.It is exciting for these significant agencies to request Glycoscience be taught in high school science classes as well as undergraduate and graduate education. This will assure that future generations will know about the science.The book provides a glimpse of the Glycoscience of tomorrow and how the future of the human race will be enriched in ways only dreamed of before. The book explains where Glycoscience can take us today and tomorrow.Four FACTS about Smart SugarsMost Smart Sugars are: (1) unknown to the public; (2) are not sweet (some are sweet); (3) extremely beneficial to good health; and (4) the building blocks for the operating system (OS) of the human body.These specific sugars, often called glyconutrients and are unique. Contrary to common thought, glyconutrients are functional beyond just supplying energy to the body. Your body uses these sugar building blocks to construct the actual operating system (OS) of every cell.The sugars and sweeteners consumed by Westerners, such as table sugar (sucrose) and synthetic sweeteners, lower the quality of health and contribute to obesity, diabetes, and other diseases plaguing humans. Bad sugars and sweet-eners weaken the immune system and all the other vital functions of the body. The really good sugars, which I call “Royal Sugars”, or “Smart Sugars” as discussed in this book, can actually help modulate your immune system and balance your hormones which is vital to your health and longevity.Prior to fifty or so years ago our ancestors ate more unprocessed foods and natural sweeteners containing Smart Sugars. Today our foods are depleted of many nutrients and necessary Smart Sugars. It is more important today than ever to supplement our diets with these beneficial functional sugars and with natural vitamins and minerals.The answer to the healthcare crisis is to maintain good health through prevention. A strong, well modulated immune system and well functioning endocrine system are vital to your health and longevity.

Aist Today

Author :
ISBN : CHI:62419683
Genre : High technology industries
File Size : 26. 30 MB
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Author : C. Stan Tsai
ISBN : UOM:39015064124269
Genre : Medical
File Size : 80. 36 MB
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Provides an integrated presentation of the structure and function of nucleic acids, proteins, and glycans, including the latest findings from the fields of genomics, proteomics, and glycomics. It serves as a bridge between introductory biochemistry textbooks and advanced treatises on individual classes of biomacromolecules. The integrated treatment of biomacromolecules enables the reader to gain a better understanding and appreciation of both the similarities and differences among the three classes of biomacromolecules examined in the text.

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