physiological basis of aging and geriatrics fourth edition

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Physiological Basis Of Aging And Geriatrics Fourth Edition

Author : Paola S. Timiras
ISBN : 1420007092
Genre : Medical
File Size : 61. 28 MB
Format : PDF
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Extensively revised and updated to reflect the current state of knowledge in the study of aging, this Fourth Edition offers a complete profile of the aging process at all levels, from molecules and cells to demography and evolution. Written by international experts in current basic and clinical aging research, this text includes aspects of individual, comparative, and differential aging, and discussions of theories and mechanisms of aging. This invaluable reference illustrates how bodily systems, organs, and functions are affected with aging, describes how genetic and environmental factors influence age-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Well illustrated, with numerous tables and graphs, this book presents up-to-date information from internationally renowned experts in various bio-medical fields. New updated information includes: emphasis on emerging technologies and recent advances in biology and bioengineering that allow greater and longer independence of the elderly recent therapeutic developments in key diseases such as Alzheimer's, osteopenia, osteoporosis, high cholesterol, diabetes, gastritis, sexual impotence, and using transgenic animals as models of aging evaluation of the latest knowledge on the roles of oxidants and antioxidants, and correlates them with other aging-based theories expanded discussion of nutrition and physical exercise chapters on gene and stem cell interventions related to the aging process updated tables to reflect current trends, new research data, and up-to-date statistical information

Physiological Basis Of Aging And Geriatrics Third Edition

Author : Paola S. Timiras
ISBN : 0849309484
Genre : Medical
File Size : 53. 22 MB
Format : PDF, ePub, Docs
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Extensively revised and updated to reflect the current state of knowledge in the study of aging, the third edition of the bestselling Physiological Basis of Aging and Geriatrics provides an even more complete profile of the aging of individuals and populations. It includes aspects of demographic, comparative, and differential aging together with a discussion of the several theories of aging. It shows how body functions change with aging, describes how both genetic and environmental factors influence aging-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Divided into three main sections, the book first provides a broad and solid background in basic processes of biogerontology. Then it presents a survey of the aging of body systems, focusing on maintenance of optimal function and ability to adapt to environmental demands. Finally, it provides a synopsis of pharmacologic, nutritional, and physical exercise guidelines for preserving physical and mental health into old age. This book collects up-to-date information from internationally renowned experts in various biologic fields using physiology as the unifying concept. Illustrated with numerous tables and graphs, Physiological Basis of Aging and Geriatrics, Third Edition focuses on the established facts of physiological aging to provide an essential reference book for a wide spectrum of readers with different levels of biological and educational backgrounds.

Epidemiology Of Aging An Ecological Approach

Author : William Satariano
ISBN : 0763726559
Genre : Health & Fitness
File Size : 50. 10 MB
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Epidemiology of Aging: An Ecological Approach is the first title to provide a comprehensive overview of the leading topics in the epidemiology of aging, such as physical functioning, depression, and survival with the ecological model. Using this ecological model, the author highlights the causes and consequences of the aging population and illustrates that all the topics are interrelated.

Pulmonary Disease In The Elderly Patient

Author : Donald A. Mahler
ISBN : 0824787528
Genre : Medical
File Size : 71. 27 MB
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Combines basic science with practical clinical perspectives. This reference describes in detail the effects of ageing on the respiratory system, and presents the diseases that may develop in the elderly individual, including chronic obstructive pulmonary disease, lung cancer and pneumonia.

Apoptosis

Author : Victor R. Preedy
ISBN : 9781439845431
Genre : Medical
File Size : 48. 83 MB
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Targeting the key active elements in the mechanism and application of apoptosis and its therapeutic implications, Apoptosis: Modern Insights into Disease from Molecules to Man covers apoptosis from A to Z. Comprehensive in scope, it explores a wide range of topics including various cancers, asthma, and multiple sclerosis as well as alcohol induced liver disease, chronic back pain, and cardiovascular health. With 40 chapters written by highly respected authorities, this single source reference provides researchers and scientists with the foundation they need.

Best Of Five Mcqs For The Acute Medicine Sce

Author : Nigel Lane
ISBN : 9780191669682
Genre : Medical
File Size : 26. 7 MB
Format : PDF, ePub
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Best of Five MCQs for the Acute Medicine SCE is a new revision resource designed specifically for this high-stakes exam. Containing over 350 Best of Five multiple choice questions, this dedicated guide will help candidates to prepare successfully. The content mirrors the SCE in Acute Medicine Blueprint to ensure candidates are fully prepared for all the topics that may appear in the exam. Topics range from how to manage acute problems in cardiology or neurology to managing acute conditions such as poisoning. All answers have full explanations and further reading to ensure high quality self-assessment and quick recognition of areas that require further study.

Geriatric Medicine An Issue Of Veterinary Clinics Of North America Equine Practice

Author : Catherine M. McGowan
ISBN : 9780323459969
Genre : Medical
File Size : 21. 18 MB
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This issue of Veterinary Clinics of North America: Equine Practice focuses on Geriatric Emergencies. Article topics include: Demographics of aged horses, management, preventive care and disease; Dental disease in aged horses and its management; Musculoskeletal disease in aged horses and its management; Ophthalmological disorders in aged horses; Integumentary disorders including cutaneous neoplasia in the older horse; Cardiac and respiratory disease in aged horses; Endocrine disease in aged horses and its management; Exercise and rehabilitation of the older horse; and more!

Endocrinology Of Aging

Author : John E. Morley
ISBN : UOM:39015048840642
Genre : Medical
File Size : 60. 37 MB
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In Endocrinology of Aging, a panel of distinguished physicians critically reviews the clinical consequences of the endocrinological changes that occur with aging-in both men and women-and examine the use of hormonal therapy to reduce them. Topics range from bone disease and water balance in all older people, to androgen deficiency in aging males, gynecomastia, and menopause. The authors also discuss Type II diabetes in persons over 65, emphasizing the cognitive benefits of good glycemia control, and the interaction of nutrition and metabolism, focusing on hypocholesterolemia, obesity, the anorexia of aging, trace elements, and vitamins. The aging of the sympathetic nervous system and its impact on hypertension in the elderly is also covered. Timely and authoritative, Endocrinology of Aging offers endocrinologists, geriatricians, and primary care physicians critical insight into the endocrine problems of our rapidly growing elderly population. The valuable information here will greatly augment every physician's ability to enhance function in their aging patients by insightful application of modern treatment regimes and today's powerful new therapeutics.

Sex And The Origins Of Death

Author : William R. Clark
ISBN : 0198026609
Genre : Science
File Size : 67. 1 MB
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Death, for bacteria, is not inevitable. Protect a bacterium from predators, and provide it with adequate food and space to grow, and it would continue living--and reproducing asexually--forever. But a paramecium (a slightly more advanced single-cell organism), under the same ideal conditions, would stop dividing after about 200 generations--and die. Death, for paramecia and their offspring, is inevitable. Unless they have sex. If at any point during that 200 or so generations, two of the progeny of our paramecium have sex, their clock will be reset to zero. They and their progeny are granted another 200 generations. Those who fail to have sex eventually die. Immortality for bacteria is automatic; for all other living beings--including humans--immortality depends on having sex. But why is this so? Why must death be inevitable? And what is the connection between death and sexual reproduction? In Sex and the Origins of Death, William R. Clark looks at life and death at the level of the cell, as he addresses such profound questions as why we age, why death exists, and why death and sex go hand in hand. Clark reveals that there are in fact two kinds of cell death--accidental death, caused by extreme cold or heat, starvation, or physical destruction, and "programmed cell death," initiated by codes embedded in our DNA. (Bacteria have no such codes.) We learn that every cell in our body has a self-destruct program embedded into it and that cell suicide is in fact a fairly commonplace event. We also discover that virtually every aspect of a cell's life is regulated by its DNA, including its own death, that the span of life is genetically determined (identical twins on average die 36 months apart, randomly selected siblings 106 months apart), that human tissue in culture will divide some 50 times and then die (an important exception being tumor cells, which divide indefinitely). But why do our cells have such programs? Why must we die? To shed light on this question, Clark reaches far back in evolutionary history, to the moment when "inevitable death" (death from aging) first appeared. For cells during the first billion years, death, when it occurred, was accidental; there was nothing programmed into them that said they must die. But fierce competition gradually led to multicellular animals--size being an advantage against predators--and with this change came cell specialization and, most important, germ cells in which reproductive DNA was segregated. When sexual reproduction evolved, it became the dominant form of reproduction on the planet, in part because mixing DNA from two individuals corrects errors that have crept into the code. But this improved DNA made DNA in the other (somatic) cells not only superfluous, but dangerous, because somatic DNA might harbor mutations. Nature's solution to this danger, Clark concludes, was programmed death--the somatic cells must die. Unfortunately, we are the somatic cells. Death is necessary to exploit to the fullest the advantages of sexual reproduction. In Sex and the Origins of Death, William Clark ranges far and wide over fascinating terrain. Whether describing a 62-year-old man having a major heart attack (and how his myocardial cells rupture and die), or discussing curious life-forms that defy any definition of life (including bacterial spores, which can regenerate after decades of inactivity, and viruses, which are nothing more than DNA or RNA wrapped in protein), this brilliant, profound volume illuminates the miraculous workings of life at its most elemental level and finds in these tiny spaces the answers to some of our largest questions.

Prostate Cancer

Author : Leland W. K. Chung
ISBN : 9781597452243
Genre : Medical
File Size : 72. 20 MB
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Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations and advances in prostate cancer and may be used as a rapid reference text for readers. The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth. Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, provides readers with a general reference for prostate cancer from prevention to therapy and will be of value to clinicians, scientists, and administrators who strive to solve the cancer problem.

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