A thirty-year quest, from genes to pain-signaling neurons to people with a rare genetic disorder that makes them feel they are on fire. Two soldiers, both with wounds injuring the same nerve, show very different responses: one is disabled by neuropathic pain, unable to touch the injured limb because even the lightest contact triggers excruciating discomfort; the other notices numbness but no pain at all. Could the difference lie in their genes? In this book, described in the foreword by Nobel Laureate James Rothman as “so well written that it reads like a detective novel,” Stephen Waxman recounts the search for a gene that controls pain—a search spanning more than thirty years and three continents. The story moves from genes to pain-signaling neurons that scream when they should be silent to people with a rare genetic disorder who feel they are on fire. Waxman explains that if pain-signaling neurons are injured by trauma or disease, they can become hyperactive and send pain signals to the brain even without external stimulus. Studying the hyperactive mutant pain gene in man on fire syndrome has pointed the way to molecules that produce pain more broadly within the general population, in the rest of us. Waxman's account of the many steps that led to discovery of the pain gene tells the story behind the science, of how science happens.
Jay Sand moves to a small city in Nebraska looking forward to his new job in the district attorney's office. He soon becomes the target of assassins and Sergeant Cindy Jackson is assigned to work out of his office and watch his back. They stumble onto a multiple homicide in progress and are caught up in the search for the killers. The pursuit takes them from a gun battle on the streets of Omaha to a jail break in Harrisburg as they stay one step ahead of organized crime and an intelligence spook gone bad. This is a story of contemporary fiction about two professional crime fighters, their families, their peers and their opponents. It is also about their failures and their successes.
Living a Life on Fire is both inspiring and practical. David Hernandez Jr. thoroughly explains how a Christian teenager can come into a closer fellowship with God, walk in freedom, be used by God in a greater way, become powerful through prayer, and become mighty through the reading of God's word. If you know a Christian teenager who is struggling to serve God, this is the perfect book for that teen, and if you know a teenager who just wants to know God in a greater way, this is the perfect book for them also. Living a Life on Fire is full of powerful testimonies of God's saving power, captivating word illustrations, answers to some tough questions, interesting yet purposeful stories, extreme challenges, and much more! Living a Life on Fire makes the perfect gift for a teenager who wants to serve God in this ungodly generation. This book will not only challenge teenagers, but this book will also encourage, strengthen, bless, and change the teenager who reads it and applies the principles within the book.
New York Times bestselling author Walter Mosley delivers two speculative tales, in one volume, of everyday people exposed to life-altering truths. The Gift of Fire In ancient mythology, the Titan Prometheus was punished by the gods for bringing man the gift of fire—an event that set humankind on its course of knowledge. As punishment for making man as powerful as gods, Prometheus was bound to a rock; every day his immortal body was devoured by a giant eagle. But in The Gift of Fire, those chains cease to be, and the great champion of man walks from that immortal prison into present-day South Central Los Angeles. On the Head of a Pin Joshua Winterland and Ana Fried are working at Jennings-Tremont Enterprises when they make the most important discovery in the history of this world—or possibly the next. JTE is developing advanced animatronics editing techniques to create high-end movies indistinguishable from live-action. Long dead stars can now share the screen with today's A-list. But one night Joshua and Ana discover something lingering in the rendered footage...an entity that will lead them into a new age beyond the reality they have come to know. At the Publisher's request, this title is being sold without Digital Rights Management Software (DRM) applied.
In this #1 New York Times bestseller, Nora Roberts delves into the world of elite firefighters who thrive on danger and adrenaline—men and women who wouldn’t know how to live life if it wasn’t on the edge. Little else in life is as dangerous as fire jumping. But there’s also little else as thrilling—at least to Rowan Tripp. Being a Missoula smoke jumper is in Rowan’s blood: her father is a legend in the field. At this point, returning to the wilds of Montana for the season feels like coming home—even with reminders of the partner she lost last season still lingering in the air. One of the best of this year’s rookie crop, Gulliver Curry is a walking contradiction, a hotshot firefighter with a big vocabulary and a winter job at a kids’ arcade. And though Rowan, as a rule, doesn’t hook up with other smoke jumpers, Gull is convinced he can change her mind... But everything is thrown off balance when a dark presence lashes out against Rowan, looking to blame someone for last year’s tragedy. Rowan knows she can’t complicate things with Gull—any distractions in the air or on the ground could be lethal. But if she doesn’t find someone she can lean on when the heat gets intense, her life may go down in flames.
With an introduction by Eimear McBride A devastatingly powerful, moving and uplifting memoir - now a classic of its genre - that inspired others to tell their own true life stories. When our stepfather staggered home reeking of whisky, ceramic hit the wall. We got used to the smash and the next-day stain, but eventually the wallpaper began to fade . . . For Andrea Ashworth, home is not a place of comfort and solace, but of violence and fear. Her father died when she was five, leaving her close-knit, loving family to battle with poverty, abuse and the long shadow of depression. But from the ashes of 1970s Manchester and the hardships of her coming-of-age in the late 1980s, Andrea finds the courage to rise . . . Written with eye-opening honesty, rare beauty and intense power, Once in a House on Fire is a ground-breaking memoir, endearing in its humour and compassion, and life-affirming in its portrait of terrible circumstances triumphantly overcome.
The fire was visible from seventy miles away and the heat generated was so intense that a helicopter could only circle the rig at a perimeter of one mile. On the surface of the sea, a converted fishing trawler inched as close as possible, but the paint on the vessel’s hull blistered and burnt. In the water surrounding the inferno, men’s heads could be seen bobbing like apples as their yellow hard hats melted with the heat. On 6 July 1988 a series of explosions ripped through the Piper Alpha oil platform, 110 miles north-east of Aberdeen in the North Sea. Ablaze with 226 men on board, the searing temperatures caused the platform to collapse in just two hours. Only sixty-one would survive by leaping over 100 feet into the water below. Newly updated for the thirtieth year since the tragedy, Fire in the Night by journalist Stephen McGinty tells in gripping detail the devastating story of that summer evening. Combining interviews with survivors, witness statements and transcripts from the official inquiry into the disaster, this is the moving and vivid tale of what remains the worst offshore oil-rig disaster to date.
Returning to the land of Confidence Game and The Bright and the Dark, Michelle M. Welch revisits the Five Countries, where magic is suspect, loyalty drives a hard bargain, and war is just a misstep away. Now, as a devastating plague takes its deadly course, a quest as fragile as a dream begins. . . . Rindell Jorren, the twenty-year-old son of a governor of Dabion, is unsuited to follow in his powerful father’s footsteps. Aimless and timid, Rindell wants only to delve into the poetry and song of the romantic cavaliers of yesteryear. But his father has other plans. To shore up his alliances, he has arranged a marriage for Rindell to a heathen Azassian. Unknown to Rindell, his future bride, Adina, is mad. Descended from the Azassian warrior who ripped the country apart centuries before, she is racked by nightmares, bound to the past–and sought by wanderers on the fringe of reality. But while Adina is blurred by insanity, Elzith the Sage sees clearly: a city burning, a search for faith, and a way to finally free humanity from its greatest scourge. . . .
Release on 2009-10 | by Dave Leonard,Bryan Rezucha
Author: Dave Leonard,Bryan Rezucha
Pubpsher: Dave Leonard
The worldâ€™s most secret society has been hidden deep inside the Catholic Church for twenty centuries. Father Joshua Cole had never heard of it even though he'd been working inside the Vatican for ten years. When he finally learned of its existence it turned his once quiet life into a nightmare. Twenty years later his nightmare got worse as he was thrown into a world he never imagined possible.