vaccine adjuvants infectious disease

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Vaccine Adjuvants

Author : Charles J. Hackett
ISBN : 9781592599707
Genre : Medical
File Size : 63. 24 MB
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A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.

Biologic Response Modifiers In Infectious Diseases An Issue Of Infectious Disease Clinics E Book

Author : Nancy M. Khardori
ISBN : 9781455712076
Genre : Medical
File Size : 84. 74 MB
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Biologic response modifiers (BRMs) are substances that stimulate the body's response to infection and disease. The body naturally produces small amounts of these substances. Scientists can produce some of them in the laboratory in large amounts for use in treating infections and other diseases. This issue reviews the use of BRMs to treat infectious diseases as well as the infectious complications of BRMs used to treat non-infectious diseases. Articles on vaccines, antibodies, interferon, and other substances are included.

Vaccine Adjuvants And Delivery Systems

Author : Manmohan Singh
ISBN : 0470134925
Genre : Science
File Size : 56. 66 MB
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The authoritative reference on recent developments in vaccinology New technologies, including recombinant protein and DNA, have sparked phenomenal progress in vaccine development and delivery systems. This unique resource brings scientists up to date on recent advances and provides the information they need to select candidate adjuvants. With chapters written by leading experts in their fields, Vaccine Adjuvants and Delivery Systems: * Provides a comprehensive overview of the rapidly evolving field and developing formulation methods * Covers cutting-edge technologies and gives the current status of adjuvants in clinical trials and those still in the pre-clinical stage * Includes detailed information on specific vaccine adjuvants, including MF59, TLR4 agonists, new iscoms, cytokines, polyphosphazenes, and more * Provides a historical perspective on the development of vaccine adjuvants and discusses the mechanisms of adjuvant actions * Covers some novel adjuvants and delivery systems and the safety evaluation of adjuvants A great reference for researchers, scientists, and students in vaccinology, biotechnology, immunology, and molecular biology, this resource is also valuable for researchers and scientists in veterinary medicine who work to prevent diseases in animals.

Infectious Diseases New Insights For The Healthcare Professional 2013 Edition

Author :
ISBN : 9781481665964
Genre : Medical
File Size : 60. 47 MB
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Infectious Diseases: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Infectious Diseases: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Infectious Diseases: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at

Vaccine Adjuvants

Author : Derek T. O’Hagan
ISBN : 0896037355
Genre : Medical
File Size : 39. 90 MB
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Annotation Vaccinologists and pharmacologists describe the preparation, characterization, and evaluation of alternative vaccine adjuvants for use in preclinical studies. Each chapter reviews a single, adjuvant and suggests why it might be preferred for a given antigen, depending on what type of immune response is desired. Alternate adjuvant choices are also presented. Methods are described in full detail and range from simple to complex preparation processes. Methods are presented by scientists who originally invented or developed them.

Novel Immunologic Adjuvants

Author : Rino Rappuoli
ISBN : 9781780840048
Genre : Electronic books
File Size : 61. 95 MB
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The study of adjuvants substances added to vaccine formulations to increase efficacy is one of the fastest growing disciplines in immunology and vaccine development. This book reviews the state-of-the-art of development of novel adjuvants and the science that supports them. There is an increasing need of novel adjuvants for preventive vaccines targeting infectious diseases for which conventional formulations have failed. New adjuvants are also needed to improve existing vaccines in the elderly, infants and chronically infected individuals that mount a suboptimal immune response. In addition, adjuvants could be very useful for the development of effective therapeutic vaccines against chronic infections and cancer. In this context, the book provides an overview of vaccine adjuvants with a special focus on their composition and mechanism of action.

Immunopharmacology Of Infectious Diseases

Author : Jeannine A. Majde
ISBN : UOM:39015012590694
Genre : Medical
File Size : 46. 78 MB
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From Innate Immunity To Immunological Memory

Author : Bali Pulendran
ISBN : 9783540326366
Genre : Medical
File Size : 35. 88 MB
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The ability to remember an antigenic encounter for several decades, even for a life time, is one of the fundamental properties of the immune system. This book assembles a collection of essays from leading experts that span the entire spectrum of immunological research, from understanding the molecular mechanisms of innate immune recognition, to dendritic cell function, to the generation and maintenance of antigen-specific B and T-cell responses.

Equine Internal Medicine E Book

Author : Stephen M. Reed
ISBN : 9781437708851
Genre : Medical
File Size : 38. 66 MB
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Develop an essential understanding of the principles of equine disease with this one-of-a-kind, problem-based resource! Extensively revised and updated with contributions from an international team of experts, Equine Internal Medicine, 3rd Edition reflects the latest clinical research in equine medicine and focuses on the basic pathophysiologic mechanisms that underlie the development of various equine diseases to help you confidently diagnose, treat, and manage patient conditions. Problem-based approach outlines how to apply the latest clinical evidence directly to the conditions you’ll encounter in practice. Pathophysiology is emphasized throughout, providing a sound basis for discussions of the diagnosis, treatment, and prognosis that follow. Body systems chapters begin with a thorough discussion of the diagnostic method appropriate to the system, including physical examination, clinical pathology, radiography, endoscopy, and ultrasonography. Flow charts, diagrams, and algorithms clarify complex material. Extensive content updates help you improve patient care with up-to-date research and clinical evidence across the full spectrum of equine practice, including: New sections on biofilm ahesins, resistance to phagocytosis, and host substrate utilization New information on changes in body weight Recent findings on fibrocoxib and diclofenac Expanded and reorganized coverage of critical care New material on inborn errors of metabolism and acquired myopathies Detailed treatment information on various disorders of the reproductive tract A new section on toxicoses causing signs related to liver disease or dysfunction Bound-in companion DVD includes more than 120 high-quality video clips that guide you through procedures related to the cardiovascular and neurologic systems.

Veterinary Microbiology And Microbial Disease

Author : P. J. Quinn
ISBN : 9781118251164
Genre : Medical
File Size : 80. 11 MB
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Microbiology is one of the core subjects for veterinary students,and since its first publication in 2002, Veterinary Microbiologyand Microbial Disease has become an essential text for students ofveterinary medicine. Fully revised and expanded, this new editionupdates the subject for pre-clinical and clinical veterinarystudents in a comprehensive manner. Individual sections deal withbacteriology, mycology and virology. Written by an academic teamwith many years of teaching experience, the book provides concisedescriptions of groups of microorganisms and the diseases whichthey cause. Microbial pathogens are discussed in separate chapterswhich provide information on the more important features of eachmicroorganism and its role in the pathogenesis of diseases ofanimals. The international and public health significance of thesepathogens are reviewed comprehensively. The final section isconcerned with the host and is organized according to the bodysystem affected. Tables, boxes and flow diagrams provide information in an easilyassimilated format. This edition contains new chapters on moleculardiagnostics and on infectious conditions of the skin,cardiovascular system, urinary tract and musculoskeletal system.Many new colour diagrams are incorporated into this edition andeach chapter has been updated. Key features of this edition: Twelve new chapters included Numerous new illustrations Each chapter has been updated Completely re-designed in full colour Fulfils the needs of veterinary students and academics inveterinary microbiology Companion website with figures from the book as Powerpoints forviewing or downloading by chapter: ahref="" Veterinary Microbiology and Microbial Disease remainsindispensable for all those studying and teaching this essentialcomponent of the veterinary curriculum.

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