vaccine adjuvants infectious disease

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Vaccine Adjuvants

Author : Charles J. Hackett
ISBN : 9781592599707
Genre : Medical
File Size : 25. 93 MB
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A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.

Biologic Response Modifiers In Infectious Diseases An Issue Of Infectious Disease Clinics E Book

Author : Nancy M. Khardori
ISBN : 9781455712076
Genre : Medical
File Size : 22. 13 MB
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Biologic response modifiers (BRMs) are substances that stimulate the body's response to infection and disease. The body naturally produces small amounts of these substances. Scientists can produce some of them in the laboratory in large amounts for use in treating infections and other diseases. This issue reviews the use of BRMs to treat infectious diseases as well as the infectious complications of BRMs used to treat non-infectious diseases. Articles on vaccines, antibodies, interferon, and other substances are included.

Vaccine Adjuvants And Delivery Systems

Author : Manmohan Singh
ISBN : 0470134925
Genre : Science
File Size : 23. 3 MB
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The authoritative reference on recent developments in vaccinology New technologies, including recombinant protein and DNA, have sparked phenomenal progress in vaccine development and delivery systems. This unique resource brings scientists up to date on recent advances and provides the information they need to select candidate adjuvants. With chapters written by leading experts in their fields, Vaccine Adjuvants and Delivery Systems: * Provides a comprehensive overview of the rapidly evolving field and developing formulation methods * Covers cutting-edge technologies and gives the current status of adjuvants in clinical trials and those still in the pre-clinical stage * Includes detailed information on specific vaccine adjuvants, including MF59, TLR4 agonists, new iscoms, cytokines, polyphosphazenes, and more * Provides a historical perspective on the development of vaccine adjuvants and discusses the mechanisms of adjuvant actions * Covers some novel adjuvants and delivery systems and the safety evaluation of adjuvants A great reference for researchers, scientists, and students in vaccinology, biotechnology, immunology, and molecular biology, this resource is also valuable for researchers and scientists in veterinary medicine who work to prevent diseases in animals.

Vaccine Adjuvants

Author : Derek T. O’Hagan
ISBN : 0896037355
Genre : Medical
File Size : 51. 69 MB
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Annotation Vaccinologists and pharmacologists describe the preparation, characterization, and evaluation of alternative vaccine adjuvants for use in preclinical studies. Each chapter reviews a single, adjuvant and suggests why it might be preferred for a given antigen, depending on what type of immune response is desired. Alternate adjuvant choices are also presented. Methods are described in full detail and range from simple to complex preparation processes. Methods are presented by scientists who originally invented or developed them.

Infectious Disease In India 1892 1940

Author : Sandhya L. Polu
ISBN : 9780230354609
Genre : Health & Fitness
File Size : 67. 62 MB
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Using case studies of cholera, plague, malaria, and yellow fever, this book analyzes how factors such as public health diplomacy, trade, imperial governance, medical technologies, and cultural norms operated within global and colonial conceptions of political and epidemiological risk to shape infectious disease policies in colonial India.

Equine Infectious Diseases E Book

Author : Debra C. Sellon
ISBN : 9781455751150
Genre : Medical
File Size : 29. 44 MB
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Ideal for both practitioners and students, this comprehensive resource covers the diagnosis, treatment, and prevention of infectious disease in horses. Organized by infectious agent — virus, bacterial and rickettsial, protazoal, and fungal — it includes complete coverage of the individual diseases caused by each type of agent. A section on clinical problems examines conditions such as ocular infections, CNS infections, and skin infections. It also addresses the importance of preventing and controlling infectious disease outbreaks with coverage of epidemiology, biosecurity, antimicrobial therapy, and recognizing foreign equine diseases. Full-color photos and illustrations provide clear, accurate representations of the clinical appearance of infectious diseases. Features the most recent information on the global threat of newly emergent diseases such as African Horse Sickness. Includes a comprehensive section on the prevention and control of infectious diseases. More than 60 expert contributors share their knowledge and expertise in equine infectious disease. A companion CD-ROM, packaged with the book, includes complete references linked to PubMed.

Immunopharmacology Of Infectious Diseases

Author : Jeannine A. Majde
ISBN : UOM:39015012590694
Genre : Medical
File Size : 28. 32 MB
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From Innate Immunity To Immunological Memory

Author : Bali Pulendran
ISBN : 9783540326366
Genre : Medical
File Size : 47. 37 MB
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The ability to remember an antigenic encounter for several decades, even for a life time, is one of the fundamental properties of the immune system. This book assembles a collection of essays from leading experts that span the entire spectrum of immunological research, from understanding the molecular mechanisms of innate immune recognition, to dendritic cell function, to the generation and maintenance of antigen-specific B and T-cell responses.


Author : Gregg N. Milligan
ISBN : 9781118636527
Genre : Medical
File Size : 36. 93 MB
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Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

Equine Internal Medicine E Book

Author : Stephen M. Reed
ISBN : 9781437708851
Genre : Medical
File Size : 72. 91 MB
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Develop an essential understanding of the principles of equine disease with this one-of-a-kind, problem-based resource! Extensively revised and updated with contributions from an international team of experts, Equine Internal Medicine, 3rd Edition reflects the latest clinical research in equine medicine and focuses on the basic pathophysiologic mechanisms that underlie the development of various equine diseases to help you confidently diagnose, treat, and manage patient conditions. Problem-based approach outlines how to apply the latest clinical evidence directly to the conditions you’ll encounter in practice. Pathophysiology is emphasized throughout, providing a sound basis for discussions of the diagnosis, treatment, and prognosis that follow. Body systems chapters begin with a thorough discussion of the diagnostic method appropriate to the system, including physical examination, clinical pathology, radiography, endoscopy, and ultrasonography. Flow charts, diagrams, and algorithms clarify complex material. Extensive content updates help you improve patient care with up-to-date research and clinical evidence across the full spectrum of equine practice, including: New sections on biofilm ahesins, resistance to phagocytosis, and host substrate utilization New information on changes in body weight Recent findings on fibrocoxib and diclofenac Expanded and reorganized coverage of critical care New material on inborn errors of metabolism and acquired myopathies Detailed treatment information on various disorders of the reproductive tract A new section on toxicoses causing signs related to liver disease or dysfunction Bound-in companion DVD includes more than 120 high-quality video clips that guide you through procedures related to the cardiovascular and neurologic systems.

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