understanding statistical error a primer for biologists

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Understanding Statistical Error

Author : Marek Gierlinski
ISBN : 9781119106913
Genre : Medical
File Size : 87. 70 MB
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This accessible introductory textbook provides a straightforward, practical explanation of how statistical analysis and error measurements should be applied in biological research. Understanding Statistical Error - A Primer for Biologists: Introduces the essential topic of error analysis to biologists Contains mathematics at a level that all biologists can grasp Presents the formulas required to calculate each confidence interval for use in practice Is based on a successful series of lectures from the author’s established course Assuming no prior knowledge of statistics, this book covers the central topics needed for efficient data analysis, ranging from probability distributions, statistical estimators, confidence intervals, error propagation and uncertainties in linear regression, to advice on how to use error bars in graphs properly. Using simple mathematics, all these topics are carefully explained and illustrated with figures and worked examples. The emphasis throughout is on visual representation and on helping the reader to approach the analysis of experimental data with confidence. This useful guide explains how to evaluate uncertainties of key parameters, such as the mean, median, proportion and correlation coefficient. Crucially, the reader will also learn why confidence intervals are important and how they compare against other measures of uncertainty. Understanding Statistical Error - A Primer for Biologists can be used both by students and researchers to deepen their knowledge and find practical formulae to carry out error analysis calculations. It is a valuable guide for students, experimental biologists and professional researchers in biology, biostatistics, computational biology, cell and molecular biology, ecology, biological chemistry, drug discovery, biophysics, as well as wider subjects within life sciences and any field where error analysis is required.

Experimental Design And Data Analysis For Biologists

Author : Gerry P. Quinn
ISBN : 9781139432894
Genre : Nature
File Size : 75. 93 MB
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An essential textbook for any student or researcher in biology needing to design experiments, sample programs or analyse the resulting data. The text begins with a revision of estimation and hypothesis testing methods, covering both classical and Bayesian philosophies, before advancing to the analysis of linear and generalized linear models. Topics covered include linear and logistic regression, simple and complex ANOVA models (for factorial, nested, block, split-plot and repeated measures and covariance designs), and log-linear models. Multivariate techniques, including classification and ordination, are then introduced. Special emphasis is placed on checking assumptions, exploratory data analysis and presentation of results. The main analyses are illustrated with many examples from published papers and there is an extensive reference list to both the statistical and biological literature. The book is supported by a website that provides all data sets, questions for each chapter and links to software.

Statistics For Biologists

Author : D. J. Finny
ISBN : 9789400958555
Genre : Science
File Size : 77. 93 MB
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This book has grown from nine hours oflectures, and about the same time in tutorial classes, that attempt to give first-year students of biology some understanding of statistics. I am convinced that such a short course should not be mathematical (though it can employ basic mathematical symbolism), and that it should give students an appreciation of statistical argument, even though this limits the amount of detailed instruction in techniques of analysis that can be included. A statistical cookery book would have been easier to write and much easier to read, but lacking in true educational content. I am more concerned to show 'why' than to present methods and rules. A further constraint, that of remaining within a reasonable price range, prevents reiteration of explanations: the reader is expected to remember what he has read, for he will not find standard terms and ideas explained afresh on each occasion of use. Many books that introduce statistics to biologists blur distinctions and evade logical issues, for example by failing to emphasize the distinction between a parameter and an estimator from a sample or by neglecting the role of randomization. On this, I aim to be un compromisingly correct - at least until reviewers point out my errors - but to do so through realistic examples rather than abstract symbolism.

A Primer Of Ecological Statistics

Author : Nicholas J. Gotelli
ISBN : 1605350648
Genre : Science
File Size : 54. 34 MB
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This book takes a broad-based approach that emphasizes the historical, cultural, political, religious, social, and economic factors that underlie an understanding of both global and domestic terrorism. This unique text-reader combines original essays with the best of the existing literature on terrorism. Each chapter of this text begins with an overview essay written by the authors, followed by two relevant and engaging articles culled from a wide variety of popular, academic, and governmental sources. This is the only major terrorism text to incorporate readings from top terrorism experts into a traditional textbook format, allowing readers to deepen their understanding of each aspect of terrorism.

The Fundamentals Of Modern Statistical Genetics

Author : Nan M. Laird
ISBN : 1441973389
Genre : Medical
File Size : 43. 37 MB
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This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. Starting with Mendel’s first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. All commonly used approaches in statistical genetics (e.g. aggregation analysis, segregation, linkage analysis, etc), are used, but the focus of the book is modern approaches to association analysis. Numerous examples illustrate key points throughout the text, both of Mendelian and complex genetic disorders. The intended audience is statisticians, biostatisticians, epidemiologists and quantitatively- oriented geneticists and health scientists wanting to learn about statistical methods for genetic analysis, whether to better analyze genetic data, or to pursue research in methodology. A background in intermediate level statistical methods is required. The authors include few mathematical derivations, and the exercises provide problems for students with a broad range of skill levels. No background in genetics is assumed.

Introduction To Computational Biology

Author : Michael S. Waterman
ISBN : 9781351437080
Genre : Mathematics
File Size : 89. 63 MB
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Biology is in the midst of a era yielding many significant discoveries and promising many more. Unique to this era is the exponential growth in the size of information-packed databases. Inspired by a pressing need to analyze that data, Introduction to Computational Biology explores a new area of expertise that emerged from this fertile field- the combination of biological and information sciences. This introduction describes the mathematical structure of biological data, especially from sequences and chromosomes. After a brief survey of molecular biology, it studies restriction maps of DNA, rough landmark maps of the underlying sequences, and clones and clone maps. It examines problems associated with reading DNA sequences and comparing sequences to finding common patterns. The author then considers that statistics of pattern counts in sequences, RNA secondary structure, and the inference of evolutionary history of related sequences. Introduction to Computational Biology exposes the reader to the fascinating structure of biological data and explains how to treat related combinatorial and statistical problems. Written to describe mathematical formulation and development, this book helps set the stage for even more, truly interdisciplinary work in biology.

Statistics For Terrified Biologists

Author : Helmut van Emden
ISBN : 9781118541678
Genre : Science
File Size : 49. 67 MB
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“We highly recommend it—not just for statistically terrified biology students and faculty, but also for those who are occasionally anxious or uncertain. In addition to being a good starting point to learn statistics, it is a useful place to return to refresh your memory.” –The Quarterly Review of Biology, March 2009 "During the entire course of my Ph.D. I've been (embarrasingly) looking for a way to teach myself the fundamentals of statistical analysis. At this point in my education, I've come to realize that often times, simply knowing the basics is enough for you to properly apply even the most complex analytical methods. ‘Statistics for Terrified Biologists’ has been just such a book - it was more than worth the $40 I spent on it, and while my 'book clubs' aren't meant to be reviews, I highly recommend the book to anyone who's in a similar predicament to my own." –Carlo Artieri's Blog Book Club The typical biology student is “hardwired” to be wary of any tasks involving the application of mathematics and statistical analyses, but the plain fact is much of biology requires interpretation of experimental data through the use of statistical methods. This unique textbook aims to demystify statistical formulae for the average biology student. Written in a lively and engaging style, Statistics for Terrified Biologists draws on the author’s 30 years of lecturing experience. One of the foremost entomologists of his generation, van Emden has an extensive track record for successfully teaching statistical methods to even the most guarded of biology students. For the first time basic methods are presented using straightforward, jargon-free language. Students are taught to use simple formulae accurately to interpret what is being measured with each test and statistic, while at the same time learning to recognize overall patterns and guiding principles. Complemented by simple illustrations and useful case studies, this is an ideal statistics resource tool for undergraduate biology and environmental science students who lack confidence in their mathematical abilities.

Molecular Biology Of The Cell

Author : Bruce Alberts
ISBN : 9781317563747
Genre : Science
File Size : 60. 85 MB
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As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.

Geometric Morphometrics For Biologists

Author : Miriam Leah Zelditch
ISBN : 9780123869043
Genre : Mathematics
File Size : 61. 84 MB
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The first edition of Geometric Morphometrics for Biologists has been the primary resource for teaching modern geometric methods of shape analysis to biologists who have a stronger background in biology than in multivariate statistics and matrix algebra. These geometric methods are appealing to biologists who approach the study of shape from a variety of perspectives, from clinical to evolutionary, because they incorporate the geometry of organisms throughout the data analysis. The second edition of this book retains the emphasis on accessible explanations, and the copious illustrations and examples of the first, updating the treatment of both theory and practice. The second edition represents the current state-of-the-art and adds new examples and summarizes recent literature, as well as provides an overview of new software and step-by-step guidance through details of carrying out the analyses. Contains updated coverage of methods, especially for sampling complex curves and 3D forms and a new chapter on applications of geometric morphometrics to forensics Offers a reorganization of chapters to streamline learning basic concepts Presents detailed instructions for conducting analyses with freely available, easy to use software Provides numerous illustrations, including graphical presentations of important theoretical concepts and demonstrations of alternative approaches to presenting results

Bioinformatics And Computational Biology Solutions Using R And Bioconductor

Author : Robert Gentleman
ISBN : 9780387293622
Genre : Computers
File Size : 34. 75 MB
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Full four-color book. Some of the editors created the Bioconductor project and Robert Gentleman is one of the two originators of R. All methods are illustrated with publicly available data, and a major section of the book is devoted to fully worked case studies. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.

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