unbiased stereology a concise guide

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Unbiased Stereology

Author : Peter R. Mouton
ISBN : 9781421402284
Genre : Medical
File Size : 30. 21 MB
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Those new to bioscience research as well as experienced practitioners will find that Mouton’s explanations are the perfect companion for stereology courses and workshops.

Neurostereology

Author : P. R. Mouton
ISBN : 9781118444184
Genre : Medical
File Size : 60. 1 MB
Format : PDF, ePub
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Stereological methods provide researchers with unparalleled quantitative data from tissue samples and allow for well-evidenced research advances in a broad range of scientific fields. Presenting a concise introduction to the methodology and application of stereological research in neuroscience, Neurostereology provides a fuller understanding of the use of these methods in research and a means for replicating successful scientific approaches. Providing sound footing for future research, Neurostereology is a useful tool for basic and clinical researchers and advanced students looking to integrate these methods into their research.

Principles And Practices Of Unbiased Stereology

Author : Peter R. Mouton
ISBN : UOM:39015055600699
Genre : Medical
File Size : 72. 83 MB
Format : PDF
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Beginning in the 1960s, scientists across a wide range of disciplines cooperated in developing unbiased -- or assumption free -- stereology, based on stochastic geometry and probability theory, as a way to estimate the parameters of irregularly shaped objects without introducing bias. In recent years these new estimation techniques, which were originally quite painstaking and time consuming, have made a great deal of headway in disciplines such as neuroscience, thanks in part to the development of computer software for their application. Prestigious journals and grant-giving organizations now require the use of unbiased stereology in the projects that they support, and this trend is expected to continue. Principles and Practices of Unbiased Stereology will fill a need in the biomedical community as a clear, user-friendly introduction to this area for the increasing number of scientists who need to learn these techniques for their research. The work moves logically from a discussion of the historical background of stereology to full explanations of terms, concepts,and tools, with the latter part of the manuscript devoted to typical stereology designs. An associated web site will feature color illustrations and video clips demonstrating stereological techniques. -- Patrick R. Hof, Mount Sinai School of Medicine

Unbiased Stereology

Author : Vyvyan Howard
ISBN : 9780203006399
Genre : Medical
File Size : 41. 60 MB
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Unbiased Stereology, Second Edition is a practical guide to making unbiased 3-D measurements via the microscope. Only those stereological techniques which have been tried and tested by real application are included. Although this technology is essentially mathematical and statistical, the authors do not immerse the reader in complex analysis, but rather provide simple heuristic explanations and references to the original proof, and illustrate the theory by analogies drawn from everyday experience. To give practical experience in application of the techniques, exercises are provided at the end of each chapter, complete with detailed worked answers.

Handbook Of Imaging In Biological Mechanics

Author : Corey P. Neu
ISBN : 9781466588141
Genre : Medical
File Size : 90. 51 MB
Format : PDF, Kindle
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Emerging imaging techniques have opened new fronts to investigate tissues, cells, and proteins. Transformative technologies such as microCT scans, super-resolution microscopy, fluorescence-based tools, and other methods now allow us to study the mechanics of cancer, dissect the origins of cellular force regulation, and examine biological specimens at the nanoscale. The Handbook of Imaging in Biological Mechanics presents the spectrum of imaging techniques used for noninvasive visualization of the morphology and mechanics of the large and small—from organs to individual macromolecules. The handbook presents optimal imaging technologies to study deformation, stress, and constitutive behavior of tissues, cells, and proteins. It also describes a suite of technologies available for probing the mechanics of surfaces, membranes, and single molecules. With chapters authored by highly recognized experts in their area, the handbook covers the entire spectrum of biomechanical and mechanobiologic imaging technologies available today.

Image Analysis Of Food Microstructure

Author : John C. Russ
ISBN : 9781420038996
Genre : Technology & Engineering
File Size : 20. 65 MB
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Image Analysis of Food Microstructure offers a condensed guide to the most common procedures and techniques by which quantitative microstructural information about food can be obtained from images. The images are selected from a broad range of food items, including macroscopic images of meat and finished products such as pizza, and the microstructures of cheeses, dough and baked goods, ice cream, fruits and vegetables, emulsions, foams, and gels. The book informs food scientists about the image processing and measurement tools used to characterize a variety of microstructures in foods, using high-quality image techniques to illustrate chemical composition, thermo-mechanical processing, and genetic and structural properties. These different types of images used to measure various aspects of structure include: macroscopic light photography, confocal light microscopy, electron microscopy, atomic force microscope images, magnetic resonance, and computed tomography. Then the text explains how to interpret images to produce data, plot the results in different graphs, and identify trends. Examples using these image analysis techniques show typical results that researchers can expect and recreate. Image Analysis of Food Microstructure summarizes the basic procedures that can be useful in various aspects of food research, from nutraceuticals to cooking and food processing. It presents the processing of images and mathematical principles needed for image analyses in a step-by-step approach to extract key information from the images obtained.

Handbook Of Clinical Gender Medicine

Author : K. Schenck-Gustafsson
ISBN : 9783805599306
Genre : Psychology
File Size : 20. 90 MB
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Gender medicine is an important new field in health and disease. It is derived from top-quality research and encompasses the biological and social determinants that underlie the susceptibility to disease and its consequences. In the future, consideration of the role of gender will undoubtedly become an integral feature of all research and clinical care. Defining the role of gender in medicine requires a broad perspective on biology and diverse skills in biomedical and social sciences. When these scientific disciplines come together, a revolution in medical care is in the making. Covering twelve different areas of medicine, the practical and useful Handbook of Clinical Gender Medicine provides up-to-date information on the role of gender in the clinical presentation, diagnosis, and management of a wide range of common diseases.

The 36 Hour Day

Author : Nancy L. Mace
ISBN : 9781421422244
Genre : Health & Fitness
File Size : 65. 59 MB
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Through five editions, The 36-Hour Day has been an essential resource for families who love and care for people with Alzheimer disease. Whether a person has Alzheimer disease or another form of dementia, he or she will face a host of problems. The 36-Hour Day will help family members and caregivers address these challenges and simultaneously cope with their own emotions and needs. Featuring useful takeaway messages and informed by recent research into the causes of and the search for therapies to prevent or cure dementia, this edition includes new information on • devices to make life simpler and safer for people who have dementia• strategies for delaying behavioral and neuropsychiatric symptoms• changes in Medicare and other health care insurance laws• palliative care, hospice care, durable power of attorney, and guardianship• dementia due to traumatic brain injury• choosing a residential care facility• support groups for caregivers, friends, and family members The central idea underlying the book—that much can be done to improve the lives of people with dementia and of those caring for them—remains the same. The 36-Hour Day is the definitive dementia care guide. -- Jeffrey Cummings, MD, ScD, Director, Cleveland Clinic Lou Ruvo Center for Brain Health

Stochastic Geometry And Its Applications

Author : Sung Nok Chiu
ISBN : 9781118658253
Genre : Mathematics
File Size : 65. 59 MB
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An extensive update to a classic text Stochastic geometry and spatial statistics play a fundamental role in many modern branches of physics, materials sciences, engineering, biology and environmental sciences. They offer successful models for the description of random two- and three-dimensional micro and macro structures and statistical methods for their analysis. The previous edition of this book has served as the key reference in its field for over 18 years and is regarded as the best treatment of the subject of stochastic geometry, both as a subject with vital applications to spatial statistics and as a very interesting field of mathematics in its own right. This edition: Presents a wealth of models for spatial patterns and related statistical methods. Provides a great survey of the modern theory of random tessellations, including many new models that became tractable only in the last few years. Includes new sections on random networks and random graphs to review the recent ever growing interest in these areas. Provides an excellent introduction to theory and modelling of point processes, which covers some very latest developments. Illustrate the forefront theory of random sets, with many applications. Adds new results to the discussion of fibre and surface processes. Offers an updated collection of useful stereological methods. Includes 700 new references. Is written in an accessible style enabling non-mathematicians to benefit from this book. Provides a companion website hosting information on recent developments in the field www.wiley.com/go/cskm Stochastic Geometry and its Applications is ideally suited for researchers in physics, materials science, biology and ecological sciences as well as mathematicians and statisticians. It should also serve as a valuable introduction to the subject for students of mathematics and statistics.

A Practical Guide To The Histology Of The Mouse

Author : Cheryl L. C. Scudamore
ISBN : 9781119941200
Genre : Medical
File Size : 87. 41 MB
Format : PDF, Kindle
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A Practical Guide to the Histology of the Mouse provides a full-colour atlas of mouse histology. Mouse models of disease are used extensively in biomedical research with many hundreds of new models being generated each year. Complete phenotypic analysis of all of these models can benefit from histologic review of the tissues. This book is aimed at veterinary and medical pathologists who are unfamiliar with mouse tissues and scientists who wish to evaluate their own mouse models. It provides practical guidance on the collection, sampling and analysis of mouse tissue samples in order to maximize the information that can be gained from these tissues. As well as illustrating the normal microscopic anatomy of the mouse, the book also describes and explains the common anatomic variations, artefacts associated with tissue collection and background lesions to help the scientist to distinguish these changes from experimentally- induced lesions. This will be an essential bench-side companion for researchers and practitioners looking for an accessible and well-illustrated guide to mouse pathology. Written by experienced pathologists and specifically tailored to the needs of scientists and histologists Full colour throughout Provides advice on sampling tissues, necropsy and recording data Includes common anatomic variations, background lesions and artefacts which will help non-experts understand whether histologic variations seen are part of the normal background or related to their experimental manipulation

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