transforming glycoscience

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Transforming Glycoscience

Author : Committee on Assessing the Importance and Impact of Glycomics and Glycosciences
ISBN : 9780309260831
Genre : Science
File Size : 68. 4 MB
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A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans--also known as carbohydrates, saccharides, or simply as sugars--play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.

Gas Phase Ir Spectroscopy And Structure Of Biological Molecules

Author : Anouk Rijs
ISBN : 9783319192048
Genre : Science
File Size : 32. 56 MB
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The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students.

Glycobiology Of The Nervous System

Author : Robert Yu
ISBN : 9781493911547
Genre : Medical
File Size : 69. 69 MB
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A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.

Experimental Glycoscience

Author : Naoyuki Taniguchi
ISBN : 4431779221
Genre : Science
File Size : 31. 34 MB
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The aim of this book is to provide experimental protocols covering many aspects of glycobiology, glycotechnology, and chemistry: biochemistry, molecular and cellular biology, genetics, physiology, and medicine. The protocols are all self-contained descriptions of the equipment and reagents needed, followed by details of the experimental procedure. In the post-genomic era, glycobiology is coming of age because more than half of proteins are glycosylated and the importance of sugar chains in various fields of life science research cannot be disregarded. Many scientists had not entered this area because glycobiology and glycoscience used to be considered difficult fields. This book, therefore, is presented much like a cookbook which can help scientists in fields other than glycobiology and glycoscience carry out research more easily.

Click Chemistry In Glycoscience

Author : Zbigniew J. Witczak
ISBN : 9781118526897
Genre : Science
File Size : 56. 50 MB
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Lays the foundation for new methods and applications of carbohydrate click chemistry Introduced by K. Barry Sharpless of The Scripps Research Institute in 2001, click chemistry mimics nature, giving researchers the tools needed to generate new substances quickly and reliably by joining small units together. With contributions from more than thirty pioneering researchers in the field, this text explores the many promising applications of click chemistry in glycoscience. Readers will learn both the basic concepts of carbohydrate click chemistry as well as its many biomedical applications, including synthetic antigens, analogs of cell-surface receptors, immobilized enzymes, targeted drug delivery systems, and multivalent cancer vaccines. Click Chemistry in Glycoscience examines a broad range of methodologies and strategies that have emerged from this rapidly evolving field. Each chapter describes new approaches, ideas, consequences, and applications resulting from the introduction of click processes. Divided into four sections, the book covers: Click chemistry strategies and decoupling Thio-click chemistry of carbohydrates Carbohydrate click chemistry for novel synthetic targets Carbohydrate click chemistry in biomedical sciences Thoroughly researched, the book reflects the most recent findings published in the literature. Diagrams and figures throughout the book enable readers to more easily grasp complex concepts and reaction processes. At the end of each chapter, references lead to the primary literature for further investigation of individual topics. The application of click chemistry to carbohydrates has tremendous implications for research. With this book as their guide, researchers have a solid foundation from which they can develop new methods and applications of carbohydrate click chemistry, including new carbohydrate-based therapeutics.

Glycoscience

Author : Arnold E. Stütz
ISBN : 9783540413837
Genre : Science
File Size : 31. 81 MB
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With contributions by numerous experts

Berichte Zur Lebensmittelsicherheit 2005

Author : Peter Brandt
ISBN : 9783764383473
Genre : Science
File Size : 61. 83 MB
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Lebensmittelmonitoring - das von Bund und Ländern durchgeführte Untersuchungsprogramm - ergänzt die amtliche Lebensmittelüberwachung der Bundesländer. Lebensmittelüberwachung kontrolliert die Einhaltung lebensmittelrechtlicher Vorschriften v.a. durch verdachts- und risikoorientierte Untersuchungen. Das Lebensmittelmonitoring hingegen misst und bewertet - wiederholt und repräsentativ - den Gehalt unerwünschter Stoffe (z.B. Pflanzenschutzmittel, Schwermetalle) in und auf Lebensmitteln. Es erkennt Risiken für Verbraucher und stellt sie ab. 2005 wurden 5159 Proben von 50 Lebensmitteln bzw. -gruppen in- und ausländischer Herkunft untersucht.

Kompendium Systembiologie

Author : Andreas Kremling
ISBN : 9783834886071
Genre : Science
File Size : 75. 93 MB
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Das Buch beschreibt die Grundlagen der mathematischen Modellierung zellulärer Systeme. Nach einer Klassifikation von Modellen wird schwerpunktmäßig auf deterministische Modelle eingegangen und für alle relevanten zellulären Prozesse entsprechende Gleichungen angegeben. Anschließend werden eine Reihe von Verfahren zur Modellanalyse vorgestellt. Etwas kürzer werden Verfahren zum Reverse Engineering und zur Analyse von Netzwerkgraphen abgehandelt. Am Ende werden noch Verfahren der Parameteridentifikation besprochen.

Partial Differential Equations Of Elliptic Type

Author : Carlo Miranda
ISBN : 9783662351475
Genre : Mathematics
File Size : 29. 70 MB
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Informationsmanagement In Der Systembiologie

Author : Silke Eckstein
ISBN : 9783642182341
Genre : Computers
File Size : 73. 17 MB
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In der Systembiologie wird untersucht, wie die Komponenten einer Zelle oder eines Organismus Interaktionsnetzwerke bilden und wie diese Zellfunktionen hervorrufen. Das Buch bietet einen Einstieg in die Systembiologie aus der Perspektive der Informatik. Die Autorin stellt die biologischen Grundlagen dar und führt ihre Leser schrittweise von den anfallenden Daten über die zur Verfügung stehenden Datenbanken und deren Integrationsmöglichkeiten hin zu verschiedenen Modellierungsansätzen. Der Band enthält zahlreiche Hinweise zu weiterführender Literatur.

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