transforming glycoscience

Download Book Transforming Glycoscience in PDF format. You can Read Online Transforming Glycoscience here in PDF, EPUB, Mobi or Docx formats.

Transforming Glycoscience

Author : Committee on Assessing the Importance and Impact of Glycomics and Glycosciences
ISBN : 9780309260831
Genre : Science
File Size : 60. 79 MB
Format : PDF, Mobi
Download : 424
Read : 904

Download Now


A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans--also known as carbohydrates, saccharides, or simply as sugars--play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.

Opportunities In Biology

Author : Board on Biology
ISBN : 9780309039277
Genre : Science
File Size : 63. 1 MB
Format : PDF, Kindle
Download : 864
Read : 1105

Download Now


Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologies--recombinant DNA, scanning tunneling microscopes, and more--are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needs--for funding, effective information systems, and other support--of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies.

Industrialization Of Biology

Author : National Research Council
ISBN : 9780309316552
Genre : Science
File Size : 69. 86 MB
Format : PDF, Mobi
Download : 408
Read : 605

Download Now


The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.

A New Biology For The 21st Century

Author : National Research Council
ISBN : 0309147867
Genre : Science
File Size : 37. 8 MB
Format : PDF, ePub, Docs
Download : 161
Read : 690

Download Now


Now more than ever, biology has the potential to contribute practical solutions to many of the major challenges confronting the United States and the world. A New Biology for the 21st Century recommends that a "New Biology" approach--one that depends on greater integration within biology, and closer collaboration with physical, computational, and earth scientists, mathematicians and engineers--be used to find solutions to four key societal needs: sustainable food production, ecosystem restoration, optimized biofuel production, and improvement in human health. The approach calls for a coordinated effort to leverage resources across the federal, private, and academic sectors to help meet challenges and improve the return on life science research in general.

Bioinformatics Converting Data To Knowledge

Author : National Research Council
ISBN : 9780309171458
Genre : Medical
File Size : 90. 81 MB
Format : PDF, Mobi
Download : 810
Read : 1185

Download Now


The goal of this workshop was to bring together bioinformatics stake holders from government, academe, and industry for a day of presentations and dialogue. Fifteen experts identified and discussed some of the most important issues raised by the current flood of biologic data. Topics explored included the importance of database curation, database integration and interoperability, consistency and standards in terminology, error prevention and correction, data provenance, ontology, the importance of maintaining privacy, data mining, and the need for more computer scientists with specialty training in bioinformatics. Although formal conclusions and recommendations will not come from this particular workshop, many insights may be gleaned about the future of this field, from the context of the discussions and presentations described here.

Glycosciences

Author : Hans-Joachim Gabius
ISBN : 9783527614721
Genre : Science
File Size : 47. 43 MB
Format : PDF, ePub, Docs
Download : 904
Read : 1165

Download Now


A comprehensive survey of the topic, ranging from basic molecular research to clinical applications. Critical reviews by leading experts in each field summarize the state of knowledge and discuss the anticipated benefits of novel approaches and strategies. These include the impact of modern analysis techniques on glycobiology, the use of synthetic neoglycoproteins, or the clinical consequences of new insights into the physiological role of lectins and glycoconjugates in pathology, oncology, immunity, neuroscience and reproduction medicine. Throughout, the aim is to separate realistic applications from mere hopes.

Glycoscience

Author : Arnold E. Stütz
ISBN : 9783540444220
Genre : Technology & Engineering
File Size : 86. 59 MB
Format : PDF, ePub, Docs
Download : 681
Read : 790

Download Now


This series presents critical reviews of the present position and future trends in modern chemical research. The short and concise reports on chemistry, each written by the world’s renowned experts, are still valid and useful after 5 or 10 years.

Click Chemistry In Glycoscience

Author : Zbigniew J. Witczak
ISBN : 9781118526897
Genre : Science
File Size : 54. 4 MB
Format : PDF, Kindle
Download : 878
Read : 910

Download Now


Lays the foundation for new methods and applications of carbohydrate click chemistry Introduced by K. Barry Sharpless of The Scripps Research Institute in 2001, click chemistry mimics nature, giving researchers the tools needed to generate new substances quickly and reliably by joining small units together. With contributions from more than thirty pioneering researchers in the field, this text explores the many promising applications of click chemistry in glycoscience. Readers will learn both the basic concepts of carbohydrate click chemistry as well as its many biomedical applications, including synthetic antigens, analogs of cell-surface receptors, immobilized enzymes, targeted drug delivery systems, and multivalent cancer vaccines. Click Chemistry in Glycoscience examines a broad range of methodologies and strategies that have emerged from this rapidly evolving field. Each chapter describes new approaches, ideas, consequences, and applications resulting from the introduction of click processes. Divided into four sections, the book covers: Click chemistry strategies and decoupling Thio-click chemistry of carbohydrates Carbohydrate click chemistry for novel synthetic targets Carbohydrate click chemistry in biomedical sciences Thoroughly researched, the book reflects the most recent findings published in the literature. Diagrams and figures throughout the book enable readers to more easily grasp complex concepts and reaction processes. At the end of each chapter, references lead to the primary literature for further investigation of individual topics. The application of click chemistry to carbohydrates has tremendous implications for research. With this book as their guide, researchers have a solid foundation from which they can develop new methods and applications of carbohydrate click chemistry, including new carbohydrate-based therapeutics.

Experimental Glycoscience

Author : Naoyuki Taniguchi
ISBN : 4431779248
Genre : Science
File Size : 81. 88 MB
Format : PDF, ePub, Mobi
Download : 691
Read : 1098

Download Now


The aim of this book is to provide experimental protocols covering many aspects of glycobiology, glycotechnology, and chemistry: biochemistry, molecular and cellular biology, genetics, physiology, and medicine. The protocols are all self-contained descriptions of the equipment and reagents needed, followed by details of the experimental procedure. In the post-genomic era, glycobiology is coming of age because more than half of proteins are glycosylated and the importance of sugar chains in various fields of life science research cannot be disregarded. Many scientists had not entered this area because glycobiology and glycoscience used to be considered difficult fields. This book, therefore, is presented much like a cookbook which can help scientists in fields other than glycobiology and glycoscience carry out research more easily.

Glycoscience Biology And Medicine

Author : Naoyuki Taniguchi
ISBN : 4431548408
Genre : Science
File Size : 37. 55 MB
Format : PDF, Docs
Download : 199
Read : 1297

Download Now


The aim of the book is to provide a succinct overview of the current status of glycoscience from both basic biological and medical points of view and to propose future directions, in order to facilitate further integrations of glycoscience with other fields in biological and medical studies. Glycans (carbohydrate oligomers) are the so-called “building blocks” of carbohydrates, nucleic acids, proteins and lipids and play major roles in many biological phenomena as well as in various pathophysiological processes. However, this area of glycoscience has been neglected from the research community because glycan structures are very complex and functionally diverse and as compared to proteins and nucleic acids simple tools for the amplification, sequencing and auto-synthesis of glycans are not available. Many scientists in other fields of research have now realized that glycosylation, i.e. the addition of glycans to a protein backbone, is the most abundant post translational modification reactions and is an important field of research and sometimes they require a glycobiology and/or glycochemistry approach to be used. It is still difficult, however, for non-expert researchers to use these techniques. This book provides numerous but simple overviews of current topics and protocols for the experiments. The book is aimed at university students and above, including non-experts in the field of glycoscience.

Top Download:

Best Books