toxoplasma gondii the model apicomplexan perspectives and methods

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Toxoplasma Gondii

Author : Louis M. Weiss
ISBN : 0080475019
Genre : Science
File Size : 51. 88 MB
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Toxoplasmosis is caused by a one-celled protozoan parasite known as Toxoplasma gondii. In the United States, it is estimated that approximately 30% of cats, the primary carriers, have been infected by T. gondii. Most humans contract toxoplasmosis by eating cyst-contaminated raw or undercooked meat, vegetables, or milk products or when they come into contact with the T. gondii eggs from cat feaces while cleaning a cat's litterbox, gardening, or playing in a sandbox. Approx 1 in 4 (more than 60 million) people in the USA are infected with the parasite, and in the UK between 0.5 and 1% of individuals become infected each year. By the age of 50, 40% of people test positive for the parasite. The predilection of this parasite is for the central nervous system (CNS) causing behavioral and personality alterations as well as fatal necrotizing encephalitis, and is especially dangerous for HIV infected patients. Though there have been tremendous strides in our understanding of the biology of Toxoplasma gondii in the last decade, there has been no systemic review of all of the information that has accumulated. Toxoplasma gondii provides the first comprehensive summary of literature on this organism by leading experts in the field who were responsible for organising the 7th International Congress on Toxoplasmosis in May 2003. It offeres systematic reviews of the biology of this pathogen as well as descriptions of the methods and resources used. Within the next year the T. gondii genome will be completed making this an indispensable research resource for biologists, physicians, parasitologists, and for all those contemplating experiments using T. gondii. * Serves as a model for understanding invasion of host cells by parasites, immune response, motility, differentiation, phylogenetics, evolution and organelle acquisition * Discusses the protocols related to genetic manipulation, cell biology and animal models while also providing reference material on available resources for working with this organism

Toxoplasma Gondii

Author : Louis M. Weiss
ISBN : 9780123965363
Genre : Science
File Size : 34. 94 MB
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This 2e of Toxoplasma gondii reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism. T. gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists. Toxoplasmosis is caused by a one-celled protozoan parasite known as T. gondii. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Most humans contract toxoplasmosis by eating contaminated, raw or undercooked meat (particularly pork), vegetables, or milk products; by coming into contact with the T. gondii eggs from cat feces; or by drinking contaminated water. The parasite damages the ocular and central nervous systems, causing behavioral and personality alterations as well as fatal necrotizing encephalitis. It is especially dangerous for the fetus of an infected pregnant woman and for individuals with compromised immune systems, such as HIV-infected patients. Completely updated, the 2e presents recent advances driven by new information on the genetics and genomics of the pathogen Provides the latest information concerning the epidemiology, diagnosis, treatment and prevention of toxoplasmosis Offers a single-source reference for a wide range of scientists and physicians working with this pathogen, including parasitologists, cell and molecular biologists, veterinarians, neuroscientists, physicians, and food scientists

Struma

Author : Johannes Köbberling
ISBN : 9783642883132
Genre : Medical
File Size : 82. 48 MB
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Biologie Von Parasiten

Author : Richard Lucius
ISBN : 9783662548622
Genre : Science
File Size : 70. 44 MB
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Die 3. vollständig überarbeitete Auflage dieses Buches führt in die Biologie parasitärer Einzeller, Würmer und Arthropoden ein. Die Autoren bieten auf Grundlage der aktuellen Systematik eine Übersicht über die verschiedenen Parasitengruppen. Ausführlich wird auf wichtige Infektionserreger, wie die der Malaria, Schlafkrankheit und Toxoplasmose eingegangen, wobei die molekularen Grundlagen der Pathogene erläutert werden. Außerdem werden Parasiten als Krankheitsüberträger dargestellt und wichtige Infektionskrankheiten, die bei Tieren vorkommen, besprochen. Daher wendet sich dieses Buch sowohl an Biologen, als auch an Veterinärmediziner und Mediziner. In den einzelnen Kapiteln kommen die Anpassungen an die parasitische Lebensweise zur Sprache. Anhand häufiger Vertreter werden exemplarisch typische Lebenszyklen, die Immunreaktionen und die resultierenden Krankheitsbilder erklärt. Viele Abbildungen veranschaulichen dabei den Text. Die Prüfungsfragen am Ende eines jeden Kapitels helfen den Lerninhalt zu rekapitulieren und zu verinnerlichen.

Molecular Detection Of Human Parasitic Pathogens

Author : Dongyou Liu
ISBN : 9781439812433
Genre : Medical
File Size : 56. 84 MB
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Traditionally, laboratory identification of parasites has relied upon various phenotypic procedures that detect their morphological, biological, and immunological features. Because these procedures tend to be time-consuming and technically demanding, molecular methods based on nucleic acid amplification technologies have been increasingly utilized for rapid, sensitive, and specific characterization of parasites. The large number of original and modified molecular protocols that have been developed over the years creates a dilemma for those attempting to adopt the most appropriate protocol for streamlined identification and detection of human pathogenic organisms of interest. Part of a four-volume collection, Molecular Detection of Human Parasitic Pathogens provides a reliable and comprehensive resource on the molecular detection and identification of major human parasitic pathogens. This volume contains expert contributions from international scientists involved in human parasitic pathogen research and diagnosis. Following a similar format throughout, each chapter includes: A brief review on the classification, biology, epidemiology, clinical features, and diagnosis of an important pathogenic parasitic genus/group An outline of clinical sample collection and preparation procedures and a selection of representative stepwise molecular protocols A discussion on further research needs relating to improved diagnoses of major human parasitic pathogens This versatile reference on molecular detection and identification of major human parasitic pathogens is an indispensable tool for upcoming and experienced medical, veterinary, and industrial laboratory scientists engaged in parasite characterization. It is also suitable as a textbook for undergraduate and graduate students majoring in parasitology.

Toxoplasmosis Of Animals And Humans Second Edition

Author : J. P. Dubey
ISBN : 1420092375
Genre : Science
File Size : 60. 17 MB
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Found worldwide from Alaska to Australasia, Toxoplasma gondii knows no geographic boundaries. The protozoan is the source of one of the most common parasitic infections in humans, livestock, companion animals, and wildlife, and has gained notoriety with its inclusion on the list of potential bioterrorism microbes. In the two decades since the publication of the first edition of Toxoplasmosis of Animals and Humans there has been an explosion of knowledge concerning T. gondii and toxoplasmosis. Still used extensively as a cell model, its genome has recently been published making it a subject of even greater scientific interest. Keeping the organizational style that made the previous edition so popular and usable, this second edition has been completely revised and updated. New in the Second Edition: Expanded information on the cultivation, maintenance, and preservation of T. gondii Expanded information on the cell biology and molecular biology of the parasite Reviews all literature from the past 20 years for each domestic animal Summarizes information on the worldwide prevalence of toxoplasmosis in pregnant women and the devastating disease it can cause in newborn Written by one of the pioneers of the field, the book provides unique information on all known host types for this parasite. It distills the voluminous and potentially confusing scientific literature that has grown geometrically in the 20 years since the publication of the first edition into a comprehensive resource. The single author approach ensures a strong foundation in the biology and a seamless integration of topics. The new edition of this groundbreaking work is the only volume to cover toxoplasmosis of animals and humans thoroughly in one source. It supplies an entry point to further research by cutting through the morass of literature to identify the most relevant references.

Der Erweiterte Ph Notyp

Author : Richard Dawkins
ISBN : 3662559676
Genre : Science
File Size : 31. 31 MB
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Der erweiterte Phänotyp - ein Klassiker der Evolutionsbiologie Richard Dawkins betrachtet dieses 1982 erschienene, 1999 überarbeitete und ergänzte Buch als seinen Hauptbeitrag zur Evolutionsbiologie und als Nachfolgewerk seines Bestsellers Das egoistische Gen. Für die deutschsprachige Übersetzung hat Richard Dawkins ein neues Vorwort verfasst. Dawkins erweitert in diesem Buch den Begriff des Phänotyps (als Summe aller Merkmale eines Individuums) auf die Auswirkungen der Gene dieses Individuums auf die Umwelt und auf andere Lebewesen. Beispiele sind die durch den Fortpflanzungstrieb des Bibers entstehenden Bauten, die drastische Auswirkungen auf die Umwelt haben können, oder das Gen eines Parasiten, welches das Verhalten seines Wirtes zum Nutzen des Parasiten (Saitenwurm) verändert. Dawkins betont mit diesem Ansatz die genzentrierte Sicht des Lebens. Im letzten Kapitel des Buches unternimmt er den Versuch, den Organismus neu zu definieren. Ich behaupte, dass die meisten Wissenschaftler, die meisten Autoren ein Werk haben, von dem sie sagen würden: Egal, ob Sie noch nie etwas von mir gelesen haben, lesen Sie wenigstens dies! Richard Dawkins

Das Protistenreich

Author : Ernst Haeckel
ISBN : 9783845744896
Genre : Science
File Size : 61. 30 MB
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Ernst Haeckel (1834 – 1919) war ein deutscher Zoologe, Philosoph und Freidenker. In seinem hier vorliegenden Werk hat er sich den Protisten angenommen. Er beschreibt diese ein- bis mehrzelligen Lebewesen und ihren Lebensraum. Am Ende findet sich ein System, in dem die Protisten verschiedenen Klassen zugeordnet sind. Sorgfältig bearbeiteter Nachdruck der Originalausgabe von 1878.

Isolation And Characterization Of Toxoplasma Gondii Bradyzoite Development Mutants

Author : Mary Patricia Juneau Craver
ISBN : WISC:89103206744
Genre :
File Size : 21. 72 MB
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Anamnese Und K Rperliche Untersuchung

Author : Julia Seiderer-Nack
ISBN : 3936427364
Genre :
File Size : 58. 97 MB
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