toxicology and clinical pharmacology of herbal products forensic science and medicine

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Toxicology And Clinical Pharmacology Of Herbal Products

Author : Melanie Johns Cupp
ISBN : 9781592590209
Genre : Medical
File Size : 79. 4 MB
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The herbai medicine industry is growing at an astounding rate. Trade group estimates suggest that total sales exceeded $4 billion dollars in 1999. Herbai remedies are for sale not just in health food stores, but in supermar kets, drug stores, and even discount warehouses. Along with the proliferation in sales has come a proliferation ofinformation sources. Not all ofthe sources are equally reliable, or even intelligible. Traditional herbalists c1assify thistle and mugwort as "cholagogues," substances used to make the gallbladder con tract and release bile. Medical school graduates are unlikely to have ever heard the term, or even accept the notion that most right-sided abdominal pain is a result of diminished bile flow. Heroin and cocaine may not be the only drugs to come from plants, but a practicing physician or toxicologist might be forgiven for thinking so. In 1998, 1264 papers were published about cocaine and only 17 about kava kava, an abused herb that is not without toxic side effects. Unfortunately, the majority of the papers about kava kava were published in journals not found in ordi nary hospitallibraries. In recognition ofthis fact, and ofthe obvious need for a reliable reference work on herbai toxicology, The Toxicology and Clinical Pharmacology 0/ Herbal Products was an early addition to our new series in Forensie Science and Medicine. It is very badly needed.

Herbal Products

Author : Timothy S. Tracy
ISBN : 9781597453837
Genre : Science
File Size : 29. 41 MB
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Herbal Products: Toxicology and Clinical Pharmacology, Second Edition builds on the informative foundation laid by its predecessor. This fully revised and expanded second edition boasts more than 200 new references that document efficacy studies and adverse effects and four new chapters devoted to dietary products. Practitioners and researchers will find that this volume is a comprehensive resource for objective clinical information.

Toxicology Of Herbal Products

Author : Olavi Pelkonen
ISBN : 9783319438061
Genre : Medical
File Size : 85. 43 MB
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This volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities. Topics include composition and quality control, toxicokinetics, interactions, safety pharmacology, approaches to studying complex mixtures including metabolomics and systems network pharmacology, and long-term toxicity. The volume also discusses various organ toxicities with a special emphasis on basic mechanisms of actions and the multicomponent and multi-target nature of herbal products. It concludes with a look to future challenges and opportunities. With contributions from noted experts, Toxicology of Herbal Products is a necessary resource for physicians, pharmacists, and toxicologists interested in complex plant-derived products.

Medical Toxicology Of Natural Substances

Author : Donald G. Barceloux
ISBN : 9781118382769
Genre : Science
File Size : 54. 65 MB
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Interest and information in the field of medical toxicology has grown rapidly, but there has never been a concise, authoritative reference focused on the subjects of natural substances, chemical and physical toxins, drugs of abuse, and pharmaceutical overdoses. Medical Toxicology of Natural Substances finally gives you an easily accessible resource for vital toxicological information on foods, plants, and animals in key areas in the natural environment.

Forensic Pathology Of Trauma

Author : Michael J. Shkrum
ISBN : 9781597451383
Genre : Medical
File Size : 89. 54 MB
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The practice of forensic pathology includes the collection and analysis of evidence in relation to a corpse in order to establish the cause of death. Knowledge of the cause of death contributes to the determination of the manner of death by medical examiners and coroners, who are occasionally assisted by law enforcement officers. In the process of establishing the cause and manner of death, representatives of various investigative bodies have several responsibilities, including explaining the death to family members, attempting to reduce the risk of similar deaths in the future, and, if applicable, apprehending the individuals who are responsible for the death. The most well-known and popular role of a forensic pathologist is in the inves- gation of cases of suspicious death; however, most medicolegal autopsies involve unexpected deaths that are above suspicion, many of which are caused by trauma (trauma being defined as any physical force or agent that causes bodily harm). The purpose of Forensic Pathology of Trauma: Common Problems for the Pathologist is to provide practical advice and information about the conduct of the forensic autopsy in cases of trauma, and to offer guidance about the analysis of the autopsy findings in these cases.

Clinical Forensic Medicine

Author : Margaret M. Stark
ISBN : 9781592599134
Genre : Medical
File Size : 34. 75 MB
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The Metropolitan Police Service (MPS), now in its 175th year, has a long tradition of working with doctors. In fact, the origin of the forensic p- sician (police surgeon) as we know him or her today, dates from the passing by Parliament of The Metropolitan Act, which received Royal Assent in June of 1829. Since then, there are records of doctors being “appointed” to the police to provide medical care to detainees and examine police officers while on duty. The MPS has been involved in the training of doctors for more than 20 years, and has been at the forefront of setting the highest standards of wo- ing practices in the area of clinical forensic medicine. Only through an awa- ness of the complex issues regarding the medical care of detainees in custody and the management of complainants of assault can justice be achieved. The MPS, therefore, has worked in partnership with the medical profession to ensure that this can be achieved. The field of clinical forensic medicine has developed in recent years into a specialty in its own right. The importance of properly trained doctors working with the police in this area cannot be overemphasized. It is essential for the protection of detainees in police custody and for the benefit of the criminal justice system as a whole. A book that assists doctors in the field is to be applauded.

A Physician S Guide To Clinical Forensic Medicine

Author : Margaret M. Stark
ISBN : 9781592590223
Genre : Medical
File Size : 40. 13 MB
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Margaret Stark and a team of authoritative experts offer a timely survey of the fundamental principles and latest developments in clinical forensic medicine. Topics range from sexual assault examination to injury interpretation, from nonaccidental injury in children, to crowd control agents. Also included are extensive discussions of the care of detainees, the management of substance abuse detainees in custody, the causes and prevention of deaths in custody, and the fundamentals of traffic medicine. In the absence of international standards of training, the authors also address the basic issues of consent, confidentiality, note-keeping, court reporting, and attendance in court. Comprehensive and authoritative, A Physicians Guide to Clinical Forensic Medicine offers forensic specialists and allied professionals a reliable, up-to-date guide to proven practices and procedures for a every variety of police inquiry requiring clinical forensic investigation.

Quality Assurance In The Pathology Laboratory

Author : Maciej J. Bogusz
ISBN : 1439802351
Genre : Law
File Size : 70. 75 MB
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Quality refers to the amount of the unpriced attributes contained in each unit of the priced attribute. Leffler, 1982 Quality is neither mind nor matter, but a third entity independent of the two, even though Quality cannot be defined, you know what it is. Pirsig, 2000 The continuous formulation of good practices and procedures across fields reflects the importance of the recognition and maintenance of "quality" for nearly every profession. The widespread introduction of point-of-care testing, centralization of activities in large core laboratories, and the increase in number and complexity of diagnostic testing worldwide has driven changes in the organization of laboratory diagnostics over the past decades. As such, laboratory diagnostics, continuously catching up to updated techniques and complex procedures, need to stay vigilant about safety and good practices adjustments. Although widely defined and quantified, the concept of quality is an intrinsic feature of the human psyche and decision making. Written to improve laboratory work, Quality Assurance in the Pathology Laboratory examines: Quality assurance of quantifiable methods applied in laboratory medicine and toxicology Quality aspects of emerging disciplines including personalized therapy and virtopsy Regulatory and logistic instrumentation that ensure quality in laboratory methods Professional education at the graduate and postgraduate levels Laboratory diagnostics substantially contributes to clinical decision making by providing valuable information for the screening, diagnosis, therapeutic monitoring, and follow-up of most—if not all—human disorders. Providing general insights into the quality assurance aspects of pathology and laboratory medicine, this book aids in improving laboratory work and, at the same time, shows the possibilities and limits of all logistic and legal tools related to quality issues.

Forensic Toxicology

Author : Nicholas T Lappas
ISBN : 9780128004647
Genre : Law
File Size : 75. 87 MB
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Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline. The text focuses on the major tenets in forensic toxicology, including an introduction to the discipline, fundamentals of forensic toxicology analysis, types of interpretations based on analytical forensic toxicology results, and reporting from the laboratory to the courtroom. Forensic Toxicology also contains appendices covering the principles of pharmacokinetics and pharmacodynamics, immunology and immunological assays, toxicogenomics, and case studies. Significant emphasis on the fundamental principles and concepts of forensic toxicology Provides students with an introduction to the core tenets of the discipline, focusing on the concepts, strategies, and methodologies utilized by professionals in the field Coauthored by a forensic toxicologist with over 40 years of experience as a professor who has taught graduate courses in forensic and analytical toxicology and who has served as a consultant and expert witness in civil and criminal cases The book's companion website, http://textbooks.elsevier.com/web/Manuals.aspx?isbn=9780127999678 features exclusive web-based content

Clinical Toxicology

Author : Frank A. Barile
ISBN : 9781420092264
Genre : Medical
File Size : 68. 47 MB
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Examining the complex interactions associated with clinical toxicological events and chemical exposure of drug administration, this updated and revised Second Edition functions as a stand-alone text or reference of clinical toxicology for professionals, students of toxicology and pharmacy, as well as forensic toxicologists, occupational healthcare workers, industrial hygienists, and safety engineers. This all-inclusive source has been updated to include the latest issues and the most current research in clinical toxicology. Key features in Clinical Toxicology: Principles and Mechanisms include: Convenient and organized categorization of compounds into therapeutic and non-therapeutic agents Tables, drawings, and figures that provide readily accessible, precise data Tables for easy usage and cross-reference to names, indications, effects, adverse reactions, and drug interactions for over 70 common herbal products The brand, generic, and street names of therapeutic agents Topics covered in the Second Edition include: Symptoms of diseases and pathology caused by toxins and clinical drugs Biological and chemical toxins, changes in protocols for managing toxic ingestions, new antidotes, changes in treatments, and the pharmacology and toxicology of herbal products The effects of biological and chemical agents cited by the U.S. and U.N. as potential bioterrorist weapons General physiology and pharmacology principles The widely distributed chemical agents and currently used therapeutic drugs that have hazardous effects

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