the language of life dna and the revolution in personalized medicine

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The Language Of Life

Author : Francis Collins
ISBN : 9781847652096
Genre : Medical
File Size : 45. 64 MB
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We are in the midst of a medical revolution: in just a few years, we will be able to have our complete DNA sequenced at an affordable cost. Analysing the content of our genomes will allow a powerful estimate of our future risks of illness - from cystic fibrosis and Huntington's disease, to cancer and diabetes - which will help us devise our own personalised blueprint of preventive medicine. This will have enormous implications on everything from our day-to-day choices like diet and exercise, to childbearing and health insurance - and it may even challenge what we thought we knew about our ethnic histories. Combining cutting-edge scientific research with practical advice, Francis Collins examines this remarkable phenomenon, which will transform healthcare worldwide. We now know that the language spoken by our DNA is the language of life itself, and in this important book Collins shows how reading that language will help save lives.

The Language Of Life

Author : Francis S. Collins
ISBN : 9781846683534
Genre : DNA
File Size : 50. 14 MB
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From the bestselling author of The Language of God.

Genomics And The Reimagining Of Personalized Medicine

Author : Richard Tutton
ISBN : 9781317129400
Genre : Medical
File Size : 70. 55 MB
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Drawing on insights from work in medical history and sociology, this book analyzes changing meanings of personalized medicine over time, from the rise of biomedicine in the twentieth century, to the emergence of pharmacogenomics and personal genomics in the 1990s and 2000s. In the past when doctors championed personalization they did so to emphasize that patients had unique biographies and social experiences in the name of caring for their patients as individuals. However, since the middle of the twentieth century, geneticists have successfully promoted the belief that genes are implicated in why some people develop diseases and why some have adverse reactions to drugs when others do not. In doing so, they claim to offer a new way of personalizing the prediction, prevention and treatment of disease. As this book shows, the genomic reimagining of personalized medicine centres on new forms of capitalization and consumption of genetic information. While genomics promises the ultimate individualization of medicine, the author argues that personalized medicine exists in the imaginative gap between the problems and limits of current scientific practices and future prospects to individualize medical interventions. A rigorous, critical examination of the promises of genomics to transform the economics and delivery of medicine, Genomics and the Reimagining of Personalized Medicine examines the consequences of the shift towards personalization for the way we think about and act on health and disease in society. As such, it will be of interest to scholars and students of the sociology of medicine and health, science and technology studies, and health policy.

Individualized Medicine

Author : Tobias Fischer
ISBN : 9783319117195
Genre : Medical
File Size : 27. 87 MB
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In 2009 the University Medicine Greifswald launched the “Greifswald Approach to Individualized Medicine” (GANI_MED) to implement biomarker-based individualized diagnostic and therapeutic strategies in clinical settings. Individualized Medicine (IM) has led not only to controversies about its potentials, but also about its societal, ethical and health economic implications. This anthology focusses on these areas and includes – next to clinical examples illustrating how the integrated analysis of biomarkers leads to significant improvement of therapeutic outcomes for a subgroup of patients – chapters about the definition, history and epistemology of IM. Additionally there is a focus on conceptual philosophical questions as well as challenges for applied research ethics (informed consent process, the IT-based consent management and the handling of incidental findings). Finally it pays attention to health economic aspects. The possibilities of IM to initiate a paradigm shift in the German health care provision are investigated. Furthermore, it is asked whether the G-DRG system is ready for the implementation of such approaches into clinical routine.

Me Medicine Vs We Medicine

Author : Donna Dickenson
ISBN : 9780231534413
Genre : Medical
File Size : 34. 61 MB
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Personalized healthcare—or what the award-winning author Donna Dickenson calls "Me Medicine"—is radically transforming our longstanding "one-size-fits-all" model. Technologies such as direct-to-consumer genetic testing, pharmacogenetically developed therapies in cancer care, private umbilical cord blood banking, and neurocognitive enhancement claim to cater to an individual's specific biological character, and, in some cases, these technologies have shown powerful potential. Yet in others they have produced negligible or even negative results. Whatever is behind the rise of Me Medicine, it isn't just science. So why is Me Medicine rapidly edging out We Medicine, and how has our commitment to our collective health suffered as a result? In her cogent, provocative analysis, Dickenson examines the economic and political factors fueling the Me Medicine phenomenon and explores how, over time, this paradigm shift in how we approach our health might damage our individual and collective well-being. Historically, the measures of "We Medicine," such as vaccination and investment in public-health infrastructure, have radically extended our life spans, and Dickenson argues we've lost sight of that truth in our enthusiasm for "Me Medicine." Dickenson explores how personalized medicine illustrates capitalism's protean capacity for creating new products and markets where none existed before—and how this, rather than scientific plausibility, goes a long way toward explaining private umbilical cord blood banks and retail genetics. Drawing on the latest findings from leading scientists, social scientists, and political analysts, she critically examines four possible hypotheses driving our Me Medicine moment: a growing sense of threat; a wave of patient narcissism; corporate interests driving new niche markets; and the dominance of personal choice as a cultural value. She concludes with insights from political theory that emphasize a conception of the commons and the steps we can take to restore its value to modern biotechnology.

The Language Of Science And Faith

Author : Karl W. Giberson
ISBN : 9780830868445
Genre : Religion
File Size : 71. 79 MB
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Christians affirm that everything exists because of God--from subatomic quarks to black holes. Science often claims to explain nature without including God at all. And thinking Christians often feel forced to choose between the two. But the good news is that we don't have to make a choice. Science does not overthrow the Bible. Faith does not require rejecting science. World-renowned scientist Francis Collins, author of The Language of God, along with fellow scientist Karl Giberson show how we can embrace both. Their fascinating treatment explains how God cares for and interacts with his creation while science offers a reliable way to understand the world he made. Together they clearly answer dozens of the most common questions people ask about Darwin, evolution, the age of the earth, the Bible, the existence of God and our finely tuned universe. They also consider how their views stack up against the new atheists as well as against creationists and adherents of intelligent design. The authors disentangle the false conclusions of Christians and atheists alike about science and evolution from the actual results of research in astronomy, physics, geology and genetics. In its place they find a story of the grandeur and beauty of a world made by a supremely creative God.

Health Care In America

Author : John C. Burnham
ISBN : 9781421416090
Genre : Medical
File Size : 68. 63 MB
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In Health Care in America, historian John C. Burnham describes changes over four centuries of medicine and public health in America. Beginning with seventeenth-century concerns over personal and neighborhood illnesses, Burnham concludes with the arrival of a new epoch in American medicine and health care at the turn of the twenty-first century. From the 1600s through the 1990s, Americans turned to a variety of healers, practices, and institutions in their efforts to prevent and survive epidemics of smallpox, yellow fever, cholera, influenza, polio, and AIDS. Health care workers in all periods attended births and deaths and cared for people who had injuries, disabilities, and chronic diseases. Drawing on primary sources, classic scholarship, and a vast body of recent literature in the history of medicine and public health, Burnham finds that traditional healing, care, and medicine dominated the United States until the late nineteenth century, when antiseptic/aseptic surgery and germ theory initiated an intellectual, social, and technical transformation. He divides the age of modern medicine into several eras: physiological medicine (1910s–1930s), antibiotics (1930s–1950s), technology (1950s–1960s), environmental medicine (1970s–1980s), and, beginning around 1990, genetic medicine. The cumulating developments in each era led to today’s radically altered doctor-patient relationship and the insistent questions that swirl around the financial cost of health care. Burnham’s sweeping narrative makes sense of medical practice, medical research, and human frailties and foibles, opening the door to a new understanding of our current concerns. -- Gerald N. Grob, Rutgers, The State University of New Jersey, author of Aging Bones: A Short History of Osteoporosis

Nextgen Genealogy The Dna Connection

Author : David R. Dowell Ph.D.
ISBN : 9781610697286
Genre : Science
File Size : 50. 60 MB
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DNA testing can serve as a powerful tool that unlocks the hidden information within our bodies for family history research. This book explains how genetic genealogy works and answers the questions of genealogists and individuals seeking information on their family trees. • Presents an overview to genealogical principles and an introduction to DNA testing for nonexpert audiences • Explains how genetic genealogy can provide data from within our bodies that tells us about who we are, who our ancestors were, and what characteristics our descendants may have • Addresses key legal and ethical issues regarding DNA testing • Describes the accepted protocols of DNA collection, handling, processing, evaluation, and interpretation that make DNA information more reliable than the other kinds of genealogical information

Using Person Centered Health Analytics To Live Longer

Author : Dwight McNeill
ISBN : 9780133890143
Genre : Computers
File Size : 32. 66 MB
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The American way of producing health is failing. It continues to rank very low among developed countries on our most vital need…to live a long and healthy life. Despite the well-intentioned actions on the part of government, life sciences, and technology, the most important resource for achieving our full health potential is ourselves. This book is about how you can do so, and how others can help you. Dwight McNeill introduces person-centered health analytics (pchA) and shows how you can use it to master five everyday behaviors that cause and perpetuate most chronic diseases. Using Person-Centered Health Analytics to Live Longer combines deep insight, a comprehensive framework, and practical tools for living longer and healthier lives. It offers a clear path forward for both individuals and stakeholders, including providers, payers, health promotion companies, technology innovators, government, and analytics practitioners.

Carranza S Clinical Periodontology

Author : Michael G. Newman
ISBN : 9781455706389
Genre : Medical
File Size : 51. 38 MB
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The most widely used periodontics text, Carranza's Clinical Periodontology provides both print and online access to basic procedures as well as the latest in advanced procedures and techniques in reconstructive, esthetic, and implant therapy. Not only does this book show how to do periodontal procedures, it describes how to best manage the outcomes and explains the evidence supporting each treatment. Written by leading experts Michael Newman, Henry Takei, Perry Klokkevold, and Fermin Carranza, along with a pool of international contributors, this edition also discusses the close connection between oral health and systemic disease. A new Expert Consult website includes the entire, fully searchable contents of the book, and takes learning to a whole new level with content updates, videos, a drug database, and much more. Comprehensive coverage describes all aspects of periodontics in a single volume, including periodontal pathology, the etiology of periodontal diseases, the relationship between periodontal disease and systemic health, treatment of periodontal diseases, oral implantology, supportive treatment, and ethics, legal, and practical matters. Problem-solving, scenario-based learning opportunities use well-documented case reports to help you learn both basic and advanced procedures and techniques. 'Speed to competence' is enhanced with access to print, online, and mobile platforms. A unique approach combines evidence-based decision-making, science transfer, and classification/nomenclature throughout every chapter. A one-of-a-kind Genetic Factors and Periodontal Disease chapter examines the role of genetic factors in gum disease. In-depth information serves as an excellent foundation in preparing for the National Board Dental Exam. Expert Consult website offers fast, reliable online access to advanced material, videos, an image collection, a drug database, interactive flash cards, multiple-choice test questions, interactive references, and Pathology Consult -- plus, the entire contents of the book are fully searchable. Find core information in the book; additional, advanced information is provided online. Consult your book from any computer, anywhere in the world, for the entire life of this edition. Keep current with regular updates of the latest periodontal news and information. Follow links from biographical citations to the corresponding MEDLINE abstracts. See a comprehensive library of pathology photos. Coverage of the latest advances includes the emerging link between periodontal disease and systemic health. Full-color illustrations depict the newest developments in surgical technology. A new Multidisciplinary Approach to Dental and Periodontal Problems chapter discusses the importance of collaborative care in the practice of periodontics. Etiology of Periodontal Diseases (Part 4) provides a more comprehensive background in periodontal anatomy, physiology, and pathogenesis.

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