the genome war how craig venter tried to capture the code of life and save the world

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The Genome War

Author : James Shreeve
ISBN : 0307417069
Genre : Science
File Size : 71. 17 MB
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The long-awaited story of the science, the business, the politics, the intrigue behind the scenes of the most ferocious competition in the history of modern science—the race to map the human genome. On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life—seven years before the projected finish of the U.S. government’s Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich. Calling his company Celera (from the Latin for “speed”), he assembled a small group of scientists in an empty building in Rockville, Maryland, and set to work. At the same time, the leaders of the government program, under the direction of Francis Collins, head of the National Human Genome Research Institute at the National Institutes of Health, began to mobilize an unexpectedly unified effort to beat Venter to the prize—knowledge that had the potential to revolutionize medicine and society. The stage was set for one of the most thrilling—and important—dramas in the history of science. The Genome War is the definitive account of that drama—the race for the greatest prize biology has had to offer, told by a writer with exclusive access to Venter’s operation from start to finish. It is also the story of how one man’s ambition created a scientific Camelot where, for a moment, it seemed that the competing interests of pure science and commercial profit might be gloriously reconciled—and the national repercussions that resulted when that dream went awry. From the Hardcover edition.

Biomedizin Im Kontext

Author : Sigrid Graumann
ISBN : 3825896242
Genre : Bioethics
File Size : 76. 91 MB
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Entschl Sselt

Author : J. Craig Venter
ISBN : 3100870301
Genre :
File Size : 81. 42 MB
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Die Neandertaler Und Wir

Author : Svante Pääbo
ISBN : 9783104030326
Genre : Social Science
File Size : 22. 53 MB
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Die aufregende Geschichte der Entschlüsselung des Neandertalergenoms – und das lebendige Porträt der neuen Wissenschaft der Paläogenetik In einer folgenreichen Nacht im Jahre 1996 gelang Svante Pääbo die Entschlüsselung der ersten DNA-Sequenzen eines Neandertalers. Eine Sensation! Die verblüffenden Erkenntnisse revolutionierten unser Bild von der Entwicklung des Homo sapiens. Jetzt erzählt der preisgekrönte Wissenschaftler seine persönliche Geschichte und verschränkt sie mit der Geschichte des neuen Gebiets, das er maßgeblich mitentwickelte: der Paläogenetik - von den ersten Analysen an altägyptischen Mumien bis hin zu Mammuts, Höhlenbären und Riesenfaultieren. Ein faszinierender Blick hinter die Kulissen der Spitzenforschung in Deutschland und der spannende Entwicklungsroman einer Wissenschaft, deren Ergebnisse vor wenigen Jahrzehnten noch niemand erahnen konnte

A Prescription For Change

Author : Michael Kinch
ISBN : 9781469630632
Genre : Medical
File Size : 33. 28 MB
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The introduction of new medicines has dramatically improved the quantity and quality of individual and public health while contributing trillions of dollars to the global economy. In spite of these past successes--and indeed because of them--our ability to deliver new medicines may be quickly coming to an end. Moving from the beginning of the twentieth century to the present, A Prescription for Change reveals how changing business strategies combined with scientific hubris have altered the way new medicines are discovered, with dire implications for both health and the economy. To explain how we have arrived at this pivotal moment, Michael Kinch recounts the history of pharmaceutical and biotechnological advances in the twentieth century. Kinch relates stories of the individuals and organizations that built the modern infrastructure that supports the development of innovative new medicines. He shows that an accelerating cycle of acquisition and downsizing is cannibalizing that infrastructure Kinch demonstrates the dismantling of the pharmaceutical and biotechnological research and development enterprises could also provide opportunities to innovate new models that sustain and expand the introduction of newer and better breakthrough medicines in the years to come.

Biocode

Author : Dawn Field
ISBN : 9780191511578
Genre : Science
File Size : 54. 39 MB
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The living world runs on genomic software - what Dawn Field and Neil Davies call the 'biocode' - the sum of all DNA on Earth. In Biocode, they tell the story of a new age of scientific discovery: the growing global effort to read and map the biocode, and what that might mean for the future. The structure of DNA was identified in 1953, and the whole human genome was mapped by 2003. Since then the new field of genomics has mushroomed and is now operating on an industrial scale. Genomes can now be sequenced rapidly and increasingly cheaply. The genomes of large numbers of organisms from mammals to microbes, have been mapped. Getting your genome sequenced is becoming affordable for many. You too can check paternity, find out where your ancestors came from, or whether you are at risk of some diseases. Some check out the pedigree of their pets, while others turn genomes into art. A stray hair is enough to crudely reconstruct the face of the owner. From reading to constructing: the first steps to creating artificial life have already been taken. Some may find the rapidity of developments, and the potential for misuse, alarming. But they also open up unprecedented possibilities. The ability to read DNA has changed how we view ourselves and understand our place in nature. From the largest oceans, to the insides of our guts, we are able to explore the biosphere as never before, from the genome up. Sequencing technology has made the invisible world of microbes visible, and biodiversity genomics is revealing whole new worlds within us and without. The findings are transformational: we are all ecosystems now. Already the first efforts at 'barcoding' entire ecological communities and creating 'genomic observatories' have begun. The future, the authors argue, will involve biocoding the entire planet.

The Routledge Companion To Literature And Science

Author : Bruce Clarke
ISBN : 9781136950421
Genre : Literary Criticism
File Size : 55. 15 MB
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With forty-four newly commissioned articles from an international cast of leading scholars, The Routledge Companion to Literature and Science traces the network of connections among literature, science, technology, mathematics, and medicine. Divided into three main sections, this volume: links diverse literatures to scientific disciplines from Artificial Intelligence to Thermodynamics surveys current theoretical and disciplinary approaches from Animal Studies to Semiotics traces the history and culture of literature and science from Greece and Rome to Postmodernism. Ranging from classical origins and modern revolutions to current developments in cultural science studies and the posthumanities, this indispensible volume offers a comprehensive resource for undergraduates, postgraduates, and researchers. With authoritative, accessible, and succinct treatments of the sciences in their literary dimensions and cultural frameworks, here is the essential guide to this vibrant area of study.

The Rough Guide To Genes Cloning

Author : Rough Guides
ISBN : 9781848362246
Genre : Science
File Size : 73. 67 MB
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What exactly is a gene? How does cloning actually work? Are designer babies a bad idea? Could we ever clone a human? The Rough Guide To Genes & Cloning answers all these questions and more. From the inside story of cells and their structure and the sleuths who cracked the genetic code to DNA cloning, twins and Dolly the sheep. Illustrated throughout with helpful pictures and diagrams, this Rough Guide turns the microscope on the things that make us what we are.

Plucked

Author : Rebecca M. Herzig
ISBN : 9781479840823
Genre : Health & Fitness
File Size : 48. 4 MB
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A cultural historian explores the history of Americans' changing attitudes towards hair removal, discussing how it was once viewed as a “mutilation” practiced by “savage” men to being expected of women, lest they be viewed as mentally ill or sexually deviant.

Green Equilibrium

Author : Christopher Wills
ISBN : 9780191654206
Genre : Science
File Size : 63. 15 MB
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In Green Equilibrium, Christopher Wills explains the rules by which ecosystems maintain a diversity of interdependent species, in particular the balance of predators and prey. Wills is both an eminent academic and a hugely experienced field-biologist. In presenting the concept of 'green equilibrium', he draws on a fascinating range of examples, including coral reefs off the densely populated Philippines, the isolated and densely forested valleys of Papua New Guinea, the changing Himalayan kingdom of Bhutan, and a Californian ranch being allowed to return to a wild state. In each case he assesses the impact of modern changes and attempts at conservation on these delicately balanced ecosystems. Wills shows how human populations, too, are an integral part of the picture. We now know from genetic evidence that over the course of history, as humans spread out of Africa, populations adapted as a result of environmental conditions. Striking new evidence indicates that some human populations carry genes from past encounters with other hominids (Neanderthals and Denisovans), as well as genetic adaptations to local hazards such as malaria. Wills argues that the most effective approaches to conserving green equilibria come out of evolutionary insights, and from close involvement of the local communities who have lived and adapted to them.

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