the dopamine receptors the receptors

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The Dopamine Receptors

Author : Kim Neve
ISBN : 9781475726350
Genre : Medical
File Size : 29. 79 MB
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Seven years after the cloning of the rat dopamine D receptor, and four 2 years after the cloning of the last mammalian dopamine receptor identified to date, this seems to be an excellent time to put together the present The Dopamine Receptors volume ofthis series, The Receptors. There has been time for considerable characterization of the novel receptor subtypes, and new, exciting lines of research from the molecular to the behavioral levels are taking shape. We asked the contributors to The Dopamine Receptors to follow the superb example set by the previous volumes in this series by writing compre hensive, historical reviews that will comprise an essential resource for nonspe cialists and newcomers to the dopamine receptor field, while at the same time providing up-to-date summaries of the most active areas of research. It is difficult these days to write about receptors without addressing the issue of receptor nomenclature. For dopamine receptors, valid arguments can be made for a system in which the subtypes are classified as belonging to the Dl or D2 classes, with letters assigned in the order of cloning (D A, D , D A, 1 18 2 D , Dc). We decided, however, that common usage counts for something, and 28 2 chose to use D , D , and D for the D2-like receptors because these names are 2 3 4 nearly unanimously used in the literature.

Dopamine Receptors And Transporters

Author : Anita Sidhu
ISBN : 9780824747428
Genre : Medical
File Size : 23. 26 MB
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"Details the function, characterization, and physiology of various dopamine receptor/transporter systems and explores their role in etiology, diagnosis, and disease management."

Dopamine Receptor Subtypes

Author : Peter Jenner
ISBN : 9051992912
Genre : Medical
File Size : 75. 26 MB
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Peripheral Dopaminergic Receptors

Author : Jean Louis
ISBN : 9781483156163
Genre : Nature
File Size : 40. 6 MB
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Peripheral Dopaminergic Receptors contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held in Strasbourg, France, on July 24-25, 1978. The papers explore advances that have been made in understanding peripheral dopaminergic receptors and cover topics organized around five themes: dopamine measurement; structure-activity relationships; peripheral actions of dopamine; effects of dopamine on the kidney; and the physiological role of dopamine in the autonomic nervous system. This volume is comprised of 36 chapters and opens with a discussion on the dopamine vascular receptor, along with its agonists and antagonists. The reader is then introduced to the physiological and clinical implications of free and conjugated dopamine; dopamine-sensitive adenylate cyclase in the renal artery of dogs; dopamine-induced relaxation of isolated dog arteries; and concentration and function of dopamine in normal and diseased blood vessels. The following chapters explore the possible involvement of endogenous substances in the cardiovascular actions of dopamine; the role of dopamine receptors as mediators of the neurogenic vasodilatation by dopaminergic agents; and implications of renal and adrenal dopamine for the role of conjugated dopamine. Studies on the peripheral cardiovascular activity of dopamine in the rat are also presented. This book will be of interest to practitioners in biosciences, pharmacology, physiology, and medicine.


Author : S.B. Dunnett
ISBN : 0080458289
Genre : Medical
File Size : 32. 61 MB
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Dopamine is a major neurotransmitter of the brain involved in the control of movement, emotion, and cognition; disturbance in dopamine function is associated with disorders like Parkinson’s disease, schizophrenia and attention deficit hyperactivity disorder. This volume of the Handbook of Chemical Neuroanatomy provides a series of in depth critical reviews of our present understanding of the most important aspects of dopamine’s organisation and disturbed function in the animal and human brain.

Serotonin And Dopamine Receptors

Author : Marshall Mckinney
ISBN : 1536132160
Genre :
File Size : 69. 73 MB
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Central And Peripheral Dopamine Receptors

Author : Pier Franco Spano
ISBN : 8876755233
Genre : Medical
File Size : 88. 22 MB
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Dopamine Receptor Technologies

Author : Mario Tiberi
ISBN : 1493921959
Genre : Medical
File Size : 40. 96 MB
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To foster a better understanding of dopamine receptor functionality, this detailed volume creates an interface between updated classical methods and new emerging technologies heretofore not available to new or seasoned researchers. Divided in five sections dedicated to experimental approaches investigating different facets of dopaminergic signal transduction, Dopamine Receptor Technologies covers epigenetic and post-transcriptional analysis, computational and biochemical techniques, visualization and imaging methods, molecular and cell biological tools, as well as behavioral assessment. The book, as a part of the popular Neuromethods series, provides insightful step-by-step protocols and methodological reviews that readers will find useful. Practical and versatile, Dopamine Receptor Technologies seeks to aid researchers in developing new pharmacological tools to improve our knowledge of in vivo roles played by each receptor subtype and the synthesis of prospective lead compounds for drug discovery.

Biology Of The Nmda Receptor

Author : Antonius M. VanDongen
ISBN : 142004415X
Genre : Science
File Size : 67. 93 MB
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The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written by one of the world’s leading authorities on NMDA receptors, Biology of the NMDA Receptor brings together virtually all the players in this important field.

D1 D2 Dopamine Receptor Interactions

Author : John L. Waddington
ISBN : 0127290451
Genre : Dopamine
File Size : 85. 8 MB
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This volume presents up-to-date comprehensive reviews of neuroscience research and theory on the fundamental interactions between the D1 and D2 dopamine receptor subtypes at numerous levels of investigation-from molecular biology and neuroanatomy, through electrophysiology, to the psychopharmacology of multiple forms of behavior, putative clinical significance, and therapeutic potential. This volume seeks to stand as a reference source on the evolution of the concept of D1: D2 interactions, on their substrates and psychopharmacological roles and, in such a continually evolving field, to look to the future. The Neuroscience Perspectives series aims to provide an all-round view of a current topic of great interest in neuroscience from the biochemical, pharmacological, and physiological standpoints together with the potential therapeutic applications. * SPECIAL FEATURES: * This is the ninth in Neuroscience Perspectives. * A Volume in Neuroscience Perspectives following series aim of providing all-round view of a current topic of great interest in Neuroscience from the biochemical, pharmacological and physiological standpoints together with the potential therapeutic applications. * The brain dopamine receptor has been the subject of intense interest for the past ten years owing to its involvement in motor and psychotic conditions. It is the target for the development of potential new drugs for eg. Schizophrenia and Parkinsons Diseases. Two subtypes of receptor have been found (D1 and D2). This book, edited by a respected expert in the field, examines the history of the topic, biochemistry, molecular biology and mode of interaction of the subtypes, and the therapeutic potential of the scientific discoveries, in the format of Neuroscience Perspectives. An issue of Nature in October 1990 led with the reported discovery of a D3 receptor. The implications of this for future research will be discussed in the final chapter.

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