the digital patient advancing healthcare research and education wiley series in modeling and simulation

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The Digital Patient

Author : C. D. Combs
ISBN : 9781118952764
Genre : Mathematics
File Size : 55. 86 MB
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A modern guide to computational models and constructive simulation for personalized patient care using the Digital Patient The healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers. The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible human The physiological human The virtual human Research in systems biology Multi-scale modeling Personalized medicine Self-quantification Visualization Computational modeling Interdisciplinary collaboration The Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.

The Profession Of Modeling And Simulation

Author : Andreas Tolk
ISBN : 9781119288084
Genre : Technology & Engineering
File Size : 33. 40 MB
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The definite guide to the theory, knowledge, technical expertise, and ethical considerations that define the M&S profession From traffic control to disaster management, supply chain analysis to military logistics, healthcare management to new drug discovery, modeling and simulation (M&S) has become an essential tool for solving countless real-world problems. M&S professionals are now indispensable to how things get done across virtually every aspect of modern life. This makes it all the more surprising that, until now, no effort has been made to systematically codify the core theory, knowledge, and technical expertise needed to succeed as an M&S professional. This book brings together contributions from experts at the leading edge of the modeling and simulation profession, worldwide, who share their priceless insights into issues which are fundamental to professional success and career development in this critically important field. Running as a common thread throughout the book is an emphasis on several key aspects of the profession, including the essential body of knowledge underlying the M&S profession; the technical discipline of M&S; the ethical standards that should guide professional conduct; and the economic and commercial challenges today’s M&S professionals face. • Demonstrates applications of M&S tools and techniques in a variety of fields—such as engineering, operations research, and cyber environments—with over 500 types of simulations • Highlights professional and academic aspects of the field, including preferred programming languages, professional academic and certification programs, and key international societies • Shows why M&S professionals must be fully versed in the theory, concepts, and tools needed to address the challenges of cyber environments The Profession of Modeling and Simulation is a valuable resource for M&S practitioners, developers, and researchers working in industry and government. Simulation professionals, including administrators, managers, technologists, faculty members, and scholars within the physical sciences, life sciences, and engineering fields will find it highly useful, as will students planning to pursue a career in the M&S profession. “ …nearly three dozen experts in Modeling and Simulation (M&S) come together to make a compelling case for the recognition of M&S as a profession… Important reading for anyone seeking to elevate the standing of this vital field.” Alfred (Al) Grasso, President & CEO, The MITRE Corporation Andreas Tolk, PhD, is Technology Integrator for the Modeling, Simulation, Experimentation, and Analytics Division of The MITRE Corporation, an adjunct professor in the Department of Engineering Management and Systems Engineering and the Department for Modeling, Simulation, and Visualization Engineering at Old Dominion University, and an SCS fellow. Tuncer Ören, PhD, is Professor Emeritus of Computer Science at the University of Ottawa. He is an SCS fellow and an inductee to SCS Modeling and Simulation Hall of Fame. His research interests include advancing methodologies, ethics, body of knowledge, and terminology of modeling and simulation.

Spatial Agent Based Simulation Modeling In Public Health

Author : S. M. Niaz Arifin
ISBN : 9781118964354
Genre : Mathematics
File Size : 47. 78 MB
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Presents an overview of the complex biological systems used within a global public health setting and features a focus on malaria analysis Bridging the gap between agent-based modeling and simulation (ABMS) and geographic information systems (GIS), Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology provides a useful introduction to the development of agent-based models (ABMs) by following a conceptual and biological core model of Anopheles gambiae for malaria epidemiology. Using spatial ABMs, the book includes mosquito (vector) control interventions and GIS as two example applications of ABMs, as well as a brief description of epidemiology modeling. In addition, the authors discuss how to most effectively integrate spatial ABMs with a GIS. The book concludes with a combination of knowledge from entomological, epidemiological, simulation-based, and geo-spatial domains in order to identify and analyze relationships between various transmission variables of the disease. Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology also features: Location-specific mosquito abundance maps that play an important role in malaria control activities by guiding future resource allocation for malaria control and identifying hotspots for further investigation Discussions on the best modeling practices in an effort to achieve improved efficacy, cost-effectiveness, ecological soundness, and sustainability of vector control for malaria An overview of the various ABMs, GIS, and spatial statistical methods used in entomological and epidemiological studies, as well as the model malaria study A companion website with computer source code and flowcharts of the spatial ABM and a landscape generator tool that can simulate landscapes with varying spatial heterogeneity of different types of resources including aquatic habitats and houses Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology is an excellent reference for professionals such as modeling and simulation experts, GIS experts, spatial analysts, mathematicians, statisticians, epidemiologists, health policy makers, as well as researchers and scientists who use, manage, or analyze infectious disease data and/or infectious disease-related projects. The book is also ideal for graduate-level courses in modeling and simulation, bioinformatics, biostatistics, public health and policy, and epidemiology. S. M. Niaz Arifin, PhD, is Research Assistant Professor in the Department of Computer Science and Engineering at the University of Notre Dame. A member of The Society for Computer Simulation, and American Society of Tropical Medicine and Hygiene, and the recipient of The American Society of Tropical Medicine and Hygiene Travel Award in 2011, his research interests include agent-based modeling and simulation, public health, data warehousing, and geographic information systems. Gregory R. Madey, PhD, is Research Professor in the Department of Computer Science and Engineering at the University of Notre Dame. A member of The Society for Computer Simulation, Institute of Electrical and Electronics Engineers Computer Society, and American Society of Tropical Medicine and Hygiene, his research interests include agent-based modeling and simulation, cyberinfrastructure, bioinformatics, biocomplexity, e-Technologies, open source software, disaster management, and health informatics. Frank H. Collins, PhD, is Professor in the Department of Biological Sciences at the University of Notre Dame. His research interests include genome level studies of arthropod vectors of human pathogens, the biology of malaria vectors with a focus on the development of molecular tools that will permit better resolution of questions about vector population ecology, ecological genetics, and the epidemiology of malaria transmission.

Healthcare Simulation

Author : Laura T. Gantt
ISBN : 9781118949412
Genre : Computers
File Size : 27. 95 MB
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"With the growing use of simulation within the field of healthcare, Healthcare Simulation: A Guide for Operations Specialists provides a much needed resource for developing the roles and responsibilities of simulation operations specialists. The book illustrates the current state and evolution of the simulation professional workforce and discusses the topics necessary for the development of this pivotal role. The book promotes the value of simulation in healthcare and its associated outcomes while clarifying the operational requirements of successful simulations. Featuring numerous contributions from international experts, consultants, and specialists, Healthcare Simulation: A Guide for Operations Specialists presents advances in healthcare simulation techniques and also features:"--Provided by publishe

Modeling And Simulation In Biomedical Engineering Applications In Cardiorespiratory Physiology

Author : Willem van Meurs
ISBN : 9780071714464
Genre : Technology & Engineering
File Size : 89. 47 MB
Format : PDF
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THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation. A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications. Coverage includes: Signals and systems Model requirements Conceptual models Mathematical models Software implementation Simulation results and model validation Cardiorespiratory system model Circulation Respiration Physiologic control Sensitivity analysis of a cardiovascular model Design of model-driven acute care training simulators “Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). ...His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. ...The ample illustrations and tables also break up the text and make reading the book easier on the eyes. ...concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all these topics together under one cover and is an important contribution to biomedical literature.” --IEEE Pulse, January 2014 “This book is written by a professional engineer who is unique in that he seems to have a natural understanding of 3 key areas as follows: the hardware involved with simulators, human physiology, and mathematical modeling. Willem van Meurs is one of the inventors of the model-driven human patient simulator (HPS), and so, he is very qualified to write this book. The book is written in a clear way, using the first person throughout, in a conversational manner, with a style that involves posing questions and answering them in subsequent text. ...The book starts with a very useful introduction and background chapter, setting out the scene for the rest of the book. ...I have used his book in enhancing my own talks and understanding human patient simulation and can strongly recommend it.” --Simulation in Healthcare December, 2012 Reviewed by Mark A. Tooley, Ph.D., Department of Medical Physics and Bioengineering, Royal United Hospital, Combe Park, Bath, UK.

Understanding Lte With Matlab

Author : Houman Zarrinkoub
ISBN : 9781118443453
Genre : Technology & Engineering
File Size : 76. 20 MB
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An introduction to technical details related to the Physical Layer of the LTE standard with MATLAB® The LTE (Long Term Evolution) and LTE-Advanced are among the latest mobile communications standards, designed to realize the dream of a truly global, fast, all-IP-based, secure broadband mobile access technology. This book examines the Physical Layer (PHY) of the LTE standards by incorporating three conceptual elements: an overview of the theory behind key enabling technologies; a concise discussion regarding standard specifications; and the MATLAB® algorithms needed to simulate the standard. The use of MATLAB®, a widely used technical computing language, is one of the distinguishing features of this book. Through a series of MATLAB® programs, the author explores each of the enabling technologies, pedagogically synthesizes an LTE PHY system model, and evaluates system performance at each stage. Following this step-by-step process, readers will achieve deeper understanding of LTE concepts and specifications through simulations. Key Features: • Accessible, intuitive, and progressive; one of the few books to focus primarily on the modeling, simulation, and implementation of the LTE PHY standard • Includes case studies and testbenches in MATLAB®, which build knowledge gradually and incrementally until a functional specification for the LTE PHY is attained • Accompanying Web site includes all MATLAB® programs, together with PowerPoint slides and other illustrative examples Dr Houman Zarrinkoub has served as a development manager and now as a senior product manager with MathWorks, based in Massachusetts, USA. Within his 12 years at MathWorks, he has been responsible for multiple signal processing and communications software tools. Prior to MathWorks, he was a research scientist in the Wireless Group at Nortel Networks, where he contributed to multiple standardization projects for 3G mobile technologies. He has been awarded multiple patents on topics related to computer simulations. He holds a BSc degree in Electrical Engineering from McGill University and MSc and PhD degrees in Telecommunications from the Institut Nationale de la Recherche Scientifique, in Canada. www.wiley.com/go/zarrinkoub

Engineering Principles Of Combat Modeling And Distributed Simulation

Author : Andreas Tolk
ISBN : 9780470874295
Genre : Business & Economics
File Size : 57. 58 MB
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Chapters 1-15 written by Andreas Tolk; chapters 16-32 written by various authors.

Modeling And Simulation Support For System Of Systems Engineering Applications

Author : Larry B. Rainey
ISBN : 9781118460313
Genre : Mathematics
File Size : 70. 66 MB
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“...a much-needed handbook with contributions from well-chosen practitioners. A primary accomplishment is to provide guidance for those involved in modeling and simulation in support of Systems of Systems development, more particularly guidance that draws on well-conceived academic research to define concepts and terms, that identifies primary challenges for developers, and that suggests fruitful approaches grounded in theory and successful examples.” Paul Davis, The RAND Corporation Modeling and Simulation Support for System of Systems Engineering Applications provides a comprehensive overview of the underlying theory, methods, and solutions in modeling and simulation support for system of systems engineering. Highlighting plentiful multidisciplinary applications of modeling and simulation, the book uniquely addresses the criteria and challenges found within the field. Beginning with a foundation of concepts, terms, and categories, a theoretical and generalized approach to system of systems engineering is introduced, and real-world applications via case studies and examples are presented. A unified approach is maintained in an effort to understand the complexity of a single system as well as the context among other proximate systems. In addition, the book features: Cutting edge coverage of modeling and simulation within the field of system of systems, including transportation, system health management, space mission analysis, systems engineering methodology, and energy State-of-the-art advances within multiple domains to instantiate theoretic insights, applicable methods, and lessons learned from real-world applications of modeling and simulation The challenges of system of systems engineering using a systematic and holistic approach Key concepts, terms, and activities to provide a comprehensive, unified, and concise representation of the field A collection of chapters written by over 40 recognized international experts from academia, government, and industry A research agenda derived from the contribution of experts that guides scholars and researchers towards open questions Modeling and Simulation Support for System of Systems Engineering Applications is an ideal reference and resource for academics and practitioners in operations research, engineering, statistics, mathematics, modeling and simulation, and computer science. The book is also an excellent course book for graduate and PhD-level courses in modeling and simulation, engineering, and computer science. Larry B. Rainey, PhD, is Founder and Senior Partner at Integrity Systems and Solutions, LLC, a consulting firm that specializes in modeling and simulation within missile defense and space operations domains. With more than 20 years of systems engineering experience, Dr. Rainey has also worked for the Missile Defense Agency and other U.S. Department of Defense organizations that address system of systems challenges. He has also been a visiting assistant professor of systems engineering at the Air Force Institute of Technology at Wright-Patterson Air Force Base Ohio and an assistant professor of systems engineering at the Colorado Technical University in Colorado Springs, Colorado. Andreas Tolk, PhD, is Chief Scientist of SimIS Inc., which provides modeling and simulation services, enterprise architecture knowledge, and integration solutions to its customers. Dr. Tolk is also Adjunct Professor in the Department of Engineering Management and Systems Engineering at Old Dominion University, as well as the author of Engineering Principles of Combat Modeling and Distributed Simulation, which is published by Wiley.

Cable System Transients

Author : Akihiro Ametani
ISBN : 9781118702161
Genre : Technology & Engineering
File Size : 43. 25 MB
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A systematic and comprehensive introduction to electromagnetic transient in cable systems, written by the internationally renowned pioneer in this field Presents a systematic and comprehensive introduction to electromagnetic transient in cable systems Written by the internationally renowned pioneer in the field Thorough coverage of the state of the art on the topic, presented in a well-organized, logical style, from fundamentals and practical applications A companion website is available

Simulation In Healthcare Education

Author : Harry Owen
ISBN : 9783319265773
Genre : Medical
File Size : 43. 67 MB
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Simulation in healthcare education has a long history, yet in many ways, we have been reinventing the wheel during the last 25 years. Historically, simulators have been much more than simple models, and we can still learn from aspects of simulation used hundreds of years ago. This book gives a narrative history of the development of simulators from the early 1700s to the middle of the 20th century when simulation in healthcare appeared to all but die out. It is organized around the development of simulation in different countries and includes at the end a guide to simulators in museums and private collections throughout the world. The aim is to increase understanding of simulation in the professional education of healthcare providers by exploring the historical context of simulators that were developed in the past, what they looked like, how they were used, and examples of simulator use that led to significant harm and an erosion of standards. The book is addressed to the healthcare simulation community and historians of medicine. The latter in particular will appreciate the identification and use of historic sources written in Latin, German, Italian, French, Polish and Spanish as well as English.

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