the digital patient advancing healthcare research and education wiley series in modeling and simulation

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The Digital Patient

Author : C. D. Combs
ISBN : 9781118952771
Genre : Mathematics
File Size : 50. 20 MB
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A modern guide to computational models and constructive simulation for personalized patient care using the Digital Patient The healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers. The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible human The physiological human The virtual human Research in systems biology Multi-scale modeling Personalized medicine Self-quantification Visualization Computational modeling Interdisciplinary collaboration The Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.

The Profession Of Modeling And Simulation

Author : Andreas Tolk
ISBN : 9781119288084
Genre : Technology & Engineering
File Size : 81. 94 MB
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The definite guide to the theory, knowledge, technical expertise, and ethical considerations that define the M&S profession From traffic control to disaster management, supply chain analysis to military logistics, healthcare management to new drug discovery, modeling and simulation (M&S) has become an essential tool for solving countless real-world problems. M&S professionals are now indispensable to how things get done across virtually every aspect of modern life. This makes it all the more surprising that, until now, no effort has been made to systematically codify the core theory, knowledge, and technical expertise needed to succeed as an M&S professional. This book brings together contributions from experts at the leading edge of the modeling and simulation profession, worldwide, who share their priceless insights into issues which are fundamental to professional success and career development in this critically important field. Running as a common thread throughout the book is an emphasis on several key aspects of the profession, including the essential body of knowledge underlying the M&S profession; the technical discipline of M&S; the ethical standards that should guide professional conduct; and the economic and commercial challenges today’s M&S professionals face. • Demonstrates applications of M&S tools and techniques in a variety of fields—such as engineering, operations research, and cyber environments—with over 500 types of simulations • Highlights professional and academic aspects of the field, including preferred programming languages, professional academic and certification programs, and key international societies • Shows why M&S professionals must be fully versed in the theory, concepts, and tools needed to address the challenges of cyber environments The Profession of Modeling and Simulation is a valuable resource for M&S practitioners, developers, and researchers working in industry and government. Simulation professionals, including administrators, managers, technologists, faculty members, and scholars within the physical sciences, life sciences, and engineering fields will find it highly useful, as will students planning to pursue a career in the M&S profession. “ …nearly three dozen experts in Modeling and Simulation (M&S) come together to make a compelling case for the recognition of M&S as a profession… Important reading for anyone seeking to elevate the standing of this vital field.” Alfred (Al) Grasso, President & CEO, The MITRE Corporation Andreas Tolk, PhD, is Technology Integrator for the Modeling, Simulation, Experimentation, and Analytics Division of The MITRE Corporation, an adjunct professor in the Department of Engineering Management and Systems Engineering and the Department for Modeling, Simulation, and Visualization Engineering at Old Dominion University, and an SCS fellow. Tuncer Ören, PhD, is Professor Emeritus of Computer Science at the University of Ottawa. He is an SCS fellow and an inductee to SCS Modeling and Simulation Hall of Fame. His research interests include advancing methodologies, ethics, body of knowledge, and terminology of modeling and simulation.

Spatial Agent Based Simulation Modeling In Public Health

Author : S. M. Niaz Arifin
ISBN : 9781118964354
Genre : Mathematics
File Size : 46. 14 MB
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Presents an overview of the complex biological systems used within a global public health setting and features a focus on malaria analysis Bridging the gap between agent-based modeling and simulation (ABMS) and geographic information systems (GIS), Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology provides a useful introduction to the development of agent-based models (ABMs) by following a conceptual and biological core model of Anopheles gambiae for malaria epidemiology. Using spatial ABMs, the book includes mosquito (vector) control interventions and GIS as two example applications of ABMs, as well as a brief description of epidemiology modeling. In addition, the authors discuss how to most effectively integrate spatial ABMs with a GIS. The book concludes with a combination of knowledge from entomological, epidemiological, simulation-based, and geo-spatial domains in order to identify and analyze relationships between various transmission variables of the disease. Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology also features: Location-specific mosquito abundance maps that play an important role in malaria control activities by guiding future resource allocation for malaria control and identifying hotspots for further investigation Discussions on the best modeling practices in an effort to achieve improved efficacy, cost-effectiveness, ecological soundness, and sustainability of vector control for malaria An overview of the various ABMs, GIS, and spatial statistical methods used in entomological and epidemiological studies, as well as the model malaria study A companion website with computer source code and flowcharts of the spatial ABM and a landscape generator tool that can simulate landscapes with varying spatial heterogeneity of different types of resources including aquatic habitats and houses Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology is an excellent reference for professionals such as modeling and simulation experts, GIS experts, spatial analysts, mathematicians, statisticians, epidemiologists, health policy makers, as well as researchers and scientists who use, manage, or analyze infectious disease data and/or infectious disease-related projects. The book is also ideal for graduate-level courses in modeling and simulation, bioinformatics, biostatistics, public health and policy, and epidemiology. S. M. Niaz Arifin, PhD, is Research Assistant Professor in the Department of Computer Science and Engineering at the University of Notre Dame. A member of The Society for Computer Simulation, and American Society of Tropical Medicine and Hygiene, and the recipient of The American Society of Tropical Medicine and Hygiene Travel Award in 2011, his research interests include agent-based modeling and simulation, public health, data warehousing, and geographic information systems. Gregory R. Madey, PhD, is Research Professor in the Department of Computer Science and Engineering at the University of Notre Dame. A member of The Society for Computer Simulation, Institute of Electrical and Electronics Engineers Computer Society, and American Society of Tropical Medicine and Hygiene, his research interests include agent-based modeling and simulation, cyberinfrastructure, bioinformatics, biocomplexity, e-Technologies, open source software, disaster management, and health informatics. Frank H. Collins, PhD, is Professor in the Department of Biological Sciences at the University of Notre Dame. His research interests include genome level studies of arthropod vectors of human pathogens, the biology of malaria vectors with a focus on the development of molecular tools that will permit better resolution of questions about vector population ecology, ecological genetics, and the epidemiology of malaria transmission.

An Introduction To Cyber Modeling And Simulation

Author : Jerry M. Couretas
ISBN : 9781119420835
Genre : Technology & Engineering
File Size : 25. 51 MB
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Introduces readers to the field of cyber modeling and simulation and examines current developments in the US and internationally This book provides an overview of cyber modeling and simulation (M&S) developments. Using scenarios, courses of action (COAs), and current M&S and simulation environments, the author presents the overall information assurance process, incorporating the people, policies, processes, and technologies currently available in the field. The author ties up the various threads that currently compose cyber M&S into a coherent view of what is measurable, simulative, and usable in order to evaluate systems for assured operation. An Introduction to Cyber Modeling and Simulation provides the reader with examples of tools and technologies currently available for performing cyber modeling and simulation. It examines how decision-making processes may benefit from M&S in cyber defense. It also examines example emulators, simulators and their potential combination. The book also takes a look at corresponding verification and validation (V&V) processes, which provide the operational community with confidence in knowing that cyber models represent the real world. This book: Explores the role of cyber M&S in decision making Provides a method for contextualizing and understanding cyber risk Shows how concepts such the Risk Management Framework (RMF) leverage multiple processes and policies into a coherent whole Evaluates standards for pure IT operations, "cyber for cyber," and operational/mission cyber evaluations—"cyber for others" Develops a method for estimating both the vulnerability of the system (i.e., time to exploit) and provides an approach for mitigating risk via policy, training, and technology alternatives Uses a model-based approach An Introduction to Cyber Modeling and Simulation is a must read for all technical professionals and students wishing to expand their knowledge of cyber M&S for future professional work.

Modeling And Simulation In The Medical And Health Sciences

Author : John A. Sokolowski
ISBN : 9781118003190
Genre : Mathematics
File Size : 30. 68 MB
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This edited book is divided into three parts: Fundamentals of Medical and Health Sciences Modeling and Simulation introduces modeling and simulation in the medical and health sciences; Medical and Health Sciences Models provides the theoretical underpinnings of medical and health sciences modeling; and Modeling and Simulation Applications in Medical and Health Sciences focuses on teaching, training, and research applications. The book begins with a general discussion of modeling and simulation from the modeling and simulation discipline perspective. This discussion grounds the reader in common terminology. It also relates this terminology to concepts found in the medical and health care (MHC) area to help bridge the gap between developers and MHC practitioners. Three distinct modes of modeling and simulation are described: live, constructive, and virtual. The live approach explains the concept of using real (live) people employing real equipment for training purposes. The constructive mode is a means of engaging medical modeling and simulation. In constructive simulation, simulated people and simulated equipment are developed to augment real-world conditions for training or experimentation purposes. The virtual mode is perhaps the most fascinating as virtual operating rooms and synthetic training environments are being produced for practitioners and educators at break-neck speed. In this mode, real people are employing simulated equipment to improve physical skills and decision-making ability.

Operations Research

Author : Frederick S. Hillier
ISBN : 9783486792089
Genre : Business & Economics
File Size : 69. 92 MB
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Aus dem Inhalt: Was ist Operations Research? Überblick über die Modellierungsgrundsätze des Operations Research. Einführung in die lineare Programmierung. Die Lösung linearer Programmierungsprobleme: Das Simplexverfahren. Stochastische Prozesse. Warteschlangentheorie. Lagerhaltungstheorie. Prognoseverfahren. Markov-Entscheidungsprozesse. Reliabilität. Entscheidungstheorie. Die Theorie des Simplexverfahrens Qualitätstheorie und Sensitivitätsanalyse Spezialfälle linearer Programmierungsprobleme. Die Formulierung linearer Programmierungsmodelle und Goal-Programmierung. Weitere Algorithmen der linearen Programmierung. Netzwerkanalyse einschließlich PERT-CPM. Dynamische Optimierung. Spieltheorie. Ganzzahlige Programmierung. Nichtlineare Programmierung Simulation. Anhang. Lösungen für ausgewählte Übungsaufgaben.

Subject Guide To Books In Print

Author :
ISBN : STANFORD:36105025888517
Genre : American literature
File Size : 31. 58 MB
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Modeling And Simulation

Author : Hartmut Bossel
ISBN : 9783663108221
Genre : Technology & Engineering
File Size : 54. 33 MB
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This book is the the English Language Version of the very successful German textbook, "Modellbildung und Simulation". It provides a self-contained and complete guide to the methods and mathematical background of modeling and simulation software of dynamic systems. Furthermore, an appropriate simulation software and a collection of dynamic system models (on the accompanying disk) are highlights of the book/software-Package.Dies ist die englischsprachige Ausgabe des sehr erfolgreichen Lehrbuches "Modellbildung und Simulation". Geboten wird eine vollständige Einführung in die Methoden der Simulation dynamischer Systeme, wobei auch der notwendige mathematische Hintergrund vermittelt wird. Außerdem ist eine Simulationssoftware Bestandteil des Werkes; auf der beiliegenden Diskette befinden sich ferner 50 Beispielsysteme ("Systemzoo"), die zur spielerischen Einübung der verwendeten Verfahren hilfreich sind.

Simulationstechnik

Author : Ulrich Kramer
ISBN : 3446192352
Genre :
File Size : 86. 72 MB
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Das Lean Six Sigma Toolbook

Author : Michael L. George
ISBN : 9783800648535
Genre : Business & Economics
File Size : 64. 81 MB
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Die Referenz zum Verständnis der Konzepte und Werkzeuge von Lean Six Sigma: Six Sigma ist ein statistisches Qualitätsziel und zugleich ein Instrument des Qualitätsmanagements. Ausgangspunkt dieser auf Effizienz und Qualität ausgerichteten Methode ist die Zieldefinition. Danach wird die Fehlerabweichung von diesem Idealziel ermittelt. Ihr Kernelement ist also die Beschreibung, Messung, Analyse, Verbesserung und Überwachung von Geschäftsprozessen unter anderem mit statistischen Mitteln. Dabei orientieren sich die Ziele an Prozesskennzahlen eines Unternehmens und an den Kundenbedürfnissen. In diesem Buch werden alle wichtigen Werkzeuge zur Anwendung von Lean Six Sigma vorgestellt und systematisch auf ihre Einsatzgebiete hin eingeordnet. Detaillierte Erläuterungen helfen zu verstehen, welches Werkzeug wann, wie und warum einzusetzen ist. Aus dem Inhalt: - Voice of the Customer - Wertstromanalyse und Prozessflussdiagramme - Datenerhebung und Abweichungsanalysen - Fehlerursachen identifizieren und verifizieren - Minderung der Durchlaufzeiten und der nicht-wertschöpfenden Kosten - Komplexität und Komplexitätsanalyse - Auswahl und Pilotierung von Lösungen Michael L. George ist Chairman der George Group, der weltweit führenden Six-Sigma-Beratung. David Rowlands ist Vice President für Six Sigma bei der North American Solution Group, einer Division von Xerox. Marc Pice und John Maxey sind Mitarbeiter der George Group. Die Übersetzung dieses Buchs wurde vom Six-Sigma-Experten Dirk Dose, Partner bei der PPI AG (www.sixsigma.de), und seinem Team vorgenommen. Er verfügt über umfangreiche Beratungspraxis mit Prozessoptimierungsprojekten, bei denen Six Sigma zur Verbesserung von Geschäftsprozessen eingesetzt wurde. Lean Six Sigma ist eine der führenden Techniken zur Maximierung der Prozesseffizienz und zur Steuerung jedes Schritts eines Geschäftsprozesses. Mit dem Lean Six Sigma Toolbook werden Sie entdecken, wie Sie Ihr Unternehmen auf ein neues Niveau der Wettbewerbsfähigkeit heben können.

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