systems biology of clostridium

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Systems Biology Of Clostridium

Author : Peter Dürre
ISBN : 9781783264421
Genre : Science
File Size : 32. 10 MB
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Systems Biology of Clostridium provides a comprehensive overview of system biology approaches in clostridia, especially Clostridium acetobutylicum. Systems biology is a rapidly evolving scientific discipline that allows us to understand and predict the metabolism and its changes within the bacterium as a whole. Clostridia represent one of the largest bacterial genera. This group contains organisms with metabolic properties that hold enormous potential for biotechnological processes. A model organism is Clostridium acetobutylicum that has been, and is still used in large-scale industrial production of the solvents acetone and butanol. Systems biology offers a new way to elucidate and understand the complex regulatory network controlling the different metabolic pathways and their interactions. All aspects from the development of appropriate experimental tools to mathematical modeling are covered, including a fascinating historical account on acetone-butanol fermentation in World War II. Written by world-class experts in their fields, Systems Biology of Clostridium is an essential source of reference for all biologists, biochemists, chemists, and chemical engineers working on biotechnological fermentations or industrial applications, as well as biofuels. Contents:Metabolic and Regulatory Networks in Clostridium AcetobutylicumClostridial Gene ToolsSupporting Systems Biology of Clostridium Acetobutylicum by Proteome AnalysisComparative Genomic Analysis of the General Stress Response in Clostridium Acetobutylicum ATCC 824 and Clostridium Beijerinckii NCIMB 8052Mathematical Modeling of the pH-Induced Metabolic Shift in Clostridium AcetobutylicumMathematical Models for Clostridia: From Cultivation Description to Systems BiologyModeling Agr-Dependent Quorum Sensing in Gram-Positive BacteriaComparative Genomic Analysis of the Central Metabolism of the Solventogenic Species Clostridium acetobutylicum ATCC 824 and Clostridium Beijerinckii NCIMB 8052The Strategic Importance of Biobutanol for Japan During WWII: A Case Study of the Butanol Fermentation Process in Taiwan and Japan Readership: Biologists, chemists, biochemists and chemical engineers working on biotechnological fermentations or industrial applications in biofuels. Key Features:First comprehensive overview of systems biology in the genus ClostridiumAuthors are world class experts in the fieldKeywords:Clostridium Acetobutylicum;Metabolic Network;Regulatory Network;proteome Analysis;Systems Biology


Author : Holger Brüggemann
ISBN : 9781904455387
Genre : Science
File Size : 48. 56 MB
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"In this book internationally recognized Clostridium experts critically review the most important aspects of clostridial research, providing the first coherent picture of the organism's molecular and cellular biology in this post-genomic era. Essential reading for every clostridia researcher, from the PhD student to the experienced scientist, as it provides a timely review of current research." --Book Jacket.

Advances In Bacterial Pathogen Biology

Author :
ISBN : 9780128003053
Genre : Science
File Size : 89. 75 MB
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This volume is an up-to-date overview of the physiology of selected pathogenic bacteria. Each chapter is written by experts in the field of that organism.The focus is on biochemistry and physiology but topics of clinical relevance are included. Contributions from leading authorities Informs and updates on all the latest developments in the field

Clostridium Difficile

Author : Peter Mullany
ISBN : STANFORD:36105211741256
Genre : Medical
File Size : 76. 20 MB
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This book reviews the state of the art of methods available for the molecular analysis and investigation of virulence of the important human pathogen Clostridium difficile.

The Clostridia

Author : Julian I. Rood
ISBN : 0080542395
Genre : Science
File Size : 89. 96 MB
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The clostridia are a group of bacteria of considerable medical and economic importance and include species responsible for generating the most potent toxins known to humans. The Clostridia: Molecular Biology and Pathogenesis is a unique work, comprising the most complete reference on the clostridia for over 20 years, bringing together the results from some of the most innovative and exciting research in the past decade. Using a principle-oriented rather than taxonomic approach, the results from molecular biology research are placed in the context of their clinical significance, and the disease process as a whole. This state-of-the-art work is truly comprehensive, covering and integrating the diverse topics of genetics, physiology, pathogenesis and cell biology. Written and edited by world-renowned authorities, material is presented to give the reader an up-to-date knowledge of the pathogenic species of this important genus. Background information is followed by details of the genetics, molecular biology, biochemistry and disease mechanisms. The structure, function and mode of action of toxins and other virulence determinants is clearly presented. As such, this work will prove essential for students, teachers, research microbiologists, infectious disease clinicians, toxin specialists, and all those working in medical or veterinary bacteriology, microbial genetics and the pharmaceutical industries. Covers appropriate medical and veterinary topics Contains authoritative contributions by international experts Presents the current state of knowledge and areas for future research Truly comprehensive--covers topics from molecular biology and physiology

The Bacterial Spore

Author : Adam Driks
ISBN : 1555816754
Genre : Science
File Size : 71. 23 MB
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Presents a broad-based overview of spore biology, providing in-depth coverage of basic and applied areas of spore research. Chapters focus on important general topics as well as specialized research areas, including broad reviews of especially important topics, such as spore molecular biology, bioremediation, issues in biodefense, and food safety.

Advances In Clostridium Research And Treatment 2012 Edition

Author :
ISBN : 9781464998416
Genre : Medical
File Size : 88. 37 MB
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Advances in Clostridium Research and Treatment / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Clostridium. The editors have built Advances in Clostridium Research and Treatment / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Clostridium in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Clostridium Research and Treatment / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at

Emerging Policy Issues In Synthetic Biology

Author : OECD
ISBN : 9789264208421
Genre :
File Size : 73. 82 MB
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This book examines policy issues in synthetic biology including R&D funding, company investment, PPP arrangements and innovative financing, infrastructure requirements, education and training, intellectual property (IP), regulation, and public engagement.

The Science And Applications Of Synthetic And Systems Biology

Author : Forum on Microbial Threats
ISBN : 9780309219396
Genre : Science
File Size : 53. 45 MB
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Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Molecular Medical Microbiology

Author : Yi-Wei Tang
ISBN : 9780123977632
Genre : Science
File Size : 60. 66 MB
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The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative three-volume work is an invaluable reference source of medical bacteriology. Comprising more than 100 chapters, organized into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting-edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. Topics covered include bacterial structure, cell function, and genetics; mechanisms of pathogenesis and prevention; antibacterial agents; and infections ranging from gastrointestinal to urinary tract, centrtal nervous system, respiratory tract, and more. The first comprehensive and accessible reference on molecular medical microbiology Full color presentation througout In-depth discussion of individual pathogenic bacteria in a system-oriented approach Includes a clinical overview for each major bacterial group Presents the latest information on vaccine development, molecular technology, and diagnostic technology More than 100 chapters covering all major groups of bacteria Written by an international panel of authors who are experts in their respective disciplines

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