protein engineering applications in science medicine and industry

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Protein Engineering

Author : Raghupathy Sarma
ISBN : 9780323150309
Genre : Science
File Size : 77. 45 MB
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Protein Engineering: Applications in Science, Medicine, and Industry deals with the scientific, medical, and industrial applications of protein engineering. Topics range from protein structure and design to mutant analysis and complex systems. Applications such as production of novel antibiotics, genetic transformation of plants, and genetic engineering of bioinsecticides are described. This book is comprised of 25 chapters and begins with an overview of trends and developments in protein chemistry and their relevance to protein engineering, followed by a discussion on protein sequence data banks. Subsequent chapters explore the design and construction of biologically active peptides, including hormones; structural and functional analysis of thermophile proteins; the conformation of diphtheria toxin; and applications of surface-simulation synthesis in protein molecular recognition. The use of oligonucleotide-directed site-specific mutagenesis in functional analysis of the signal peptide for protein secretion is also considered. The results of studies on the mechanism of membrane fusion are presented. This monograph will serve as a useful guide for those who are already working on protein engineering and those who are about to start research in this field.

Encyclopaedia Of Protein Engineering

Author :
ISBN : 1785693441
Genre :
File Size : 69. 3 MB
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Protein Engineering For Industrial Biotechnology

Author : Lilia Alberghina
ISBN : 9780203303702
Genre : Medical
File Size : 38. 93 MB
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Protein engineering has proved to be one of the more fruitful technological approaches in biotechnology, being both very powerful and able to generate valuable intellectual property. This book aims to present examples in which the application of protein engineering has successfully solved problems arising in industrial biotechnology. There is a section on its use to enhance purification of recombinant proteins. The use of protein engineering to modify the activity or the stability of industrial enzymes from lipases to proteases, from carboxypeptidases to glucanases and glucosidases, and from pectin modifying enzymes to enzymes able to degrade recalcitrant compounds is extensively covered. It is shown how areas as diverse as agrofood technology, fine chemistry, detergents, bioremediation and biosensors receive significant contributions from protein and solvent engineering. The application of protein engineering to health care is also covered, from the development of new vaccines to new potential therapeutic proteins. A specific notation is given to protein engineering in the development of target molecules for drug discovery. International in scope, the many contributions are drawn from academia and industry. The text should be of interest to students and researchers in industrial biotechnology as well as to everybody interested in basic research in protein structure, molecular genetics, bio-organic chemistry, biochemistry, agrobiotechnology, pharmaceutical sciences and medicine.

Proteins Form And Function

Author : R.A. Bradshaw
ISBN : 9780080983936
Genre : Science
File Size : 74. 58 MB
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Proteins are of fundamental importance in all aspects of cell structure and function. The study of proteins has always formed a central part of biochemistry, and recent expansion in the range and sophistication of available techniques has provided a wealth of new information. The current methods and approaches used to gain a better understanding of the structure of proteins are described within this book, while other articles focus on the role of proteins within the cell. Most of the articles have appeared previously in the monthly review journal Trends in Biochemical Sciences (TIBS), with a few commissioned specifically for this collection, which should appeal to students, lecturers and researchers interested in the form and function of proteins.

Molecular Electronics And Molecular Electronic Devices

Author : Kristof Sienicki
ISBN : 0849380626
Genre : Technology & Engineering
File Size : 55. 43 MB
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Molecular Electronics and Molecular Electronic Devices is a book that provides a comprehensive review of current problems and information regarding aspects of molecular electronics and molecular electronic devices. Experimental and theoretical aspects of molecular electronics and molecular electronic devices are reviewed by distinguished researchers working in chemistry, physics, computer science, and various areas of biology. These books will be an excellent reference for physicists, chemists, electronics engineers and researchers interested in molecular electronics and molecular electronic devices.

Protein Engineering And Design

Author : Sheldon J. Park
ISBN : 1420076590
Genre : Science
File Size : 70. 4 MB
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Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to cultivate a synergistic approach to protein science. Experimental Protein Engineering The first half of the book discusses experimental approaches to protein engineering and starts by describing several high-throughput screening platforms for protein engineering. Key techniques used for diversity generation are also discussed. The next few chapters present examples of therapeutics, enzymes, biomaterials, and other proteins that have been engineered by rational or combinatorial approaches. The section finishes with a chapter on the use of non-natural amino acids in protein engineering. Computational Protein Design The second half of the book introduces computational protein design, beginning with a chapter on computational and informatics algorithms used in protein engineering. Core components of computational protein design are then discussed in detail, and examples of heuristic protein design are provided. Subsequent chapters present examples of how computational design has played a critical role in advancing the field of protein engineering. Concluding with a chapter outlining current challenges in the field, this book makes computational protein design and diversity-oriented protein engineering widely accessible to a broad audience in academia and industry alike.


Author : Anil Kumar Anal
ISBN : 9781351643634
Genre : Medical
File Size : 83. 92 MB
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This book deals with a subject of high interest and importance in all sectors, including biomedical, food, agriculture, energy, and environment. Biological systems are essential in nanotechnology, and many new applications are being developed by mimicking the natural systems. Approaching these topics from an engineering perspective, the book offers insight on the details of nanoscale fabrication processes as well as cell biology. The basics of biology and chemistry, with a focus on how to engineer the behavior of molecules at the nanoscale, are also explored and analyzed. The aim of the text is to provide the reader with broader knowledge of biological methods for signal transduction and molecular recognitions systems and how they can be replicated in bio-sensing applications. The reader will learn the basic structures and interactions of biomacromolecules for developing biocompatible and eco-friendly devices.

Protein Engineering

Author : Peter C. E. Moody
ISBN : 0199631948
Genre : Science
File Size : 70. 34 MB
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This is a clear, up-to-date review of the scientific techniques used to alter the properties of proteins. It provides a wealth of in-depth information in an accessible format, explaining the underlying principles and their useful applications. Topics covered include the analysis of mutant proteins, structure-activity relationships, and the application of protein engineering to industrial and medical problems. The book also reviews a number of areas in which recent findings have led to new ideas that are not adequately described in existing textbooks. Two-color illustrations clarify the material and help make this an ideal source of information for undergraduates and graduates in biology and medicine.


Author : Ralph A. Bradshaw
ISBN : UOM:39015049078572
Genre : Science
File Size : 22. 16 MB
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Biotechnology Current Progress

Author : Paul N. Cheremisinoff
ISBN : PSU:000018134414
Genre : Biotechnology
File Size : 41. 14 MB
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