physiological basis of aging and geriatrics fourth edition

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Extensively revised and updated to reflect the current state of knowledge in the study of aging, this Fourth Edition offers a complete profile of the aging process at all levels, from molecules and cells to demography and evolution. Written by international experts in current basic and clinical aging research, this text includes aspects of individual, comparative, and differential aging, and discussions of theories and mechanisms of aging. This invaluable reference illustrates how bodily systems, organs, and functions are affected with aging, describes how genetic and environmental factors influence age-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Well illustrated, with numerous tables and graphs, this book presents up-to-date information from internationally renowned experts in various bio-medical fields. New updated information includes: emphasis on emerging technologies and recent advances in biology and bioengineering that allow greater and longer independence of the elderly recent therapeutic developments in key diseases such as Alzheimer's, osteopenia, osteoporosis, high cholesterol, diabetes, gastritis, sexual impotence, and using transgenic animals as models of aging evaluation of the latest knowledge on the roles of oxidants and antioxidants, and correlates them with other aging-based theories expanded discussion of nutrition and physical exercise chapters on gene and stem cell interventions related to the aging process updated tables to reflect current trends, new research data, and up-to-date statistical information

Extensively revised and updated to reflect the current state of knowledge in the study of aging, the third edition of the bestselling Physiological Basis of Aging and Geriatrics provides an even more complete profile of the aging of individuals and populations. It includes aspects of demographic, comparative, and differential aging together with a discussion of the several theories of aging. It shows how body functions change with aging, describes how both genetic and environmental factors influence aging-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Divided into three main sections, the book first provides a broad and solid background in basic processes of biogerontology. Then it presents a survey of the aging of body systems, focusing on maintenance of optimal function and ability to adapt to environmental demands. Finally, it provides a synopsis of pharmacologic, nutritional, and physical exercise guidelines for preserving physical and mental health into old age. This book collects up-to-date information from internationally renowned experts in various biologic fields using physiology as the unifying concept. Illustrated with numerous tables and graphs, Physiological Basis of Aging and Geriatrics, Third Edition focuses on the established facts of physiological aging to provide an essential reference book for a wide spectrum of readers with different levels of biological and educational backgrounds.

Targeting the key active elements in the mechanism and application of apoptosis and its therapeutic implications, Apoptosis: Modern Insights into Disease from Molecules to Man covers apoptosis from A to Z. Comprehensive in scope, it explores a wide range of topics including various cancers, asthma, and multiple sclerosis as well as alcohol induced liver disease, chronic back pain, and cardiovascular health. With 40 chapters written by highly respected authorities, this single source reference provides researchers and scientists with the foundation they need.

Best of Five MCQs for the Acute Medicine SCE is a new revision resource designed specifically for this high-stakes exam. Containing over 350 Best of Five multiple choice questions, this dedicated guide will help candidates to prepare successfully. The content mirrors the SCE in Acute Medicine Blueprint to ensure candidates are fully prepared for all the topics that may appear in the exam. Topics range from how to manage acute problems in cardiology or neurology to managing acute conditions such as poisoning. All answers have full explanations and further reading to ensure high quality self-assessment and quick recognition of areas that require further study.

This fourth edition of a comprehensive text/reference that has been valued by students, educators, and practicing nurses for many years, Palliative Care Nursing continues to reflect the fundamental basic and advanced hospice and palliative care nursing competencies that are required for effective and empathetic care of patients and families. This new edition focuses on palliative care that is responsive to the demand for health care reform in America and globally. It provides the knowledge, scientific evidence, and skills needed by nurses to address the complex physical, emotional, social, and spiritual needs of patients and families within the context of a changing health care delivery system. With a focus on interprofessional collaboration, the book emphasizes the value of complementary, holistic models in promoting health, wholeness, and wellness across the illness trajectory, even as death approaches.

Epidemiology of Aging: An Ecological Approach is the first title to provide a comprehensive overview of the leading topics in the epidemiology of aging, such as physical functioning, depression, and survival with the ecological model. Using this ecological model, the author highlights the causes and consequences of the aging population and illustrates that all the topics are interrelated.

This unique book provides a concise account, written by world authorities in their fields, of how the mammalian lung grows and matures before birth and how the lungs, and their ability to function well, can be affected by the environment and by genetic factors, both before and after birth. It provides an understanding of the basis of some major lung diseases affecting infants and children. The book also deals with how the lung changes with age, and how the process of lung aging can be affected by the environment. * Discusses the mechanisms that regulate the initial events of lung morphogenesis * Provides a better understanding of the cellular and biochemical events involved in alveolarization * Development of the pulmonary immune system and how the exposure to allergens during development may lead to diseases such as asthma

Combines basic science with practical clinical perspectives. This reference describes in detail the effects of ageing on the respiratory system, and presents the diseases that may develop in the elderly individual, including chronic obstructive pulmonary disease, lung cancer and pneumonia.

A panel of leading experts integrate the latest findings from basic and clinical science to create a comprehensive treatment of the processes by which the brain acts as an endocrine organ, not only to control hormonal functions, but also to maintain homeostasis and regulate behavior. The authors-recognized both as leaders in their fields and as skilled teachers-provide systematic coverage of the analytical, anatomical, functional, clinical, and pathological aspects of neuroendocrinology. Topics range from the interactions between the nervous and endocrine systems to the regulation of reproduction, development, metabolism, fluid balance, and biological rhythms. Neuroendocrinology in Physiology and Medicine offers an unprecedented marriage of clinical and basic knowledge that has been missing from classical neuroscience, endocrinology, and physiology texts. It will teach today's medical students and serve researchers as a valuable reference to this rapidly growing field.

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