oral controlled release formulation design and drug delivery theory to practice

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Oral Controlled Release Formulation Design And Drug Delivery

Author : Hong Wen
ISBN : 1118060326
Genre : Science
File Size : 20. 90 MB
Format : PDF, Mobi
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This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.

Oral Controlled Release Formulation Design And Drug Delivery

Author : Hong Wen
ISBN : 9780470640470
Genre : Science
File Size : 30. 12 MB
Format : PDF, Docs
Download : 529
Read : 930

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This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.

Developing Solid Oral Dosage Forms

Author : Yihong Qiu
ISBN : 9780128026373
Genre : Medical
File Size : 21. 14 MB
Format : PDF, Kindle
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Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. Chapters have been added, combined, deleted, and completely revised as necessary to produce a comprehensive, well-organized, valuable reference for industry professionals and academics engaged in all aspects of the development process. New and important topics include spray drying, amorphous solid dispersion using hot-melt extrusion, modeling and simulation, bioequivalence of complex modified-released dosage forms, biowaivers, and much more. Written and edited by an international team of leading experts with experience and knowledge across industry, academia, and regulatory settings Includes new chapters covering the pharmaceutical applications of surface phenomenon, predictive biopharmaceutics and pharmacokinetics, the development of formulations for drug discovery support, and much more Presents new case studies throughout, and a section completely devoted to regulatory aspects, including global product regulation and international perspectives

Engineering Polymer Systems For Improved Drug Delivery

Author : Rebecca A. Bader
ISBN : 9781118747803
Genre : Social Science
File Size : 76. 77 MB
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Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

Melt Extrusion

Author : Michael A. Repka
ISBN : 9781461484325
Genre : Medical
File Size : 26. 87 MB
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This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applications of a variety of extrusion processes, including various pharma grade extruders. In addition, the downstream production of films, pellets and tablets, for example, for oral and other delivery routes, are presented and discussed utilizing melt extrusion. This book is the first of its kind that discusses extensively the well-developed science of extrusion technology as applied to pharmaceutical drug product development and manufacturing. By covering a wide range of relevant topics, the text brings together all technical information necessary to develop and market pharmaceutical dosage forms that meet current quality and regulatory requirements. As extrusion technology continues to be refined further, usage of extruder systems and the array of applications will continue to expand, but the core technologies will remain the same.

Medizin In China

Author : Paul Ulrich Unschuld
ISBN : UCAL:B5146975
Genre : Medicine
File Size : 31. 40 MB
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3d And 4d Printing In Biomedical Applications

Author : Mohammed Maniruzzaman
ISBN : 9783527344437
Genre : Science
File Size : 41. 67 MB
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Ein professioneller Leitfaden zu 3D- und 4D-Drucktechniken in der Biomedizin und Pharmazie. 3D and 4D Printing in Biomedical Applications führt fundiert in 3D- und 4D-Drucktechniken in der Biomedizin und Pharmazie ein. Dieses Fachbuch enthält Beiträge von internationalen Wissenschaftlern und Industrieexperten und bietet einen Überblick über das Thema, aktuelle Forschungsergebnisse und Innovationen zu Anwendungen in der Pharmazie und Biomedizin. Untersucht werden Prozessoptimierung, Innovationsprozesse, Engineering- und Plattformtechnologien. Darüber hinaus informiert das Werk über Entwicklungen in der Biomedizin, u. a. über Formgedächtnispolymere, Biofabrikation in 4D und Knochen aus dem Drucker. Eine Fülle von Themen werden behandelt und näher beleuchtet: Potenzial des 3D-Drucks für die Wirkstoffverabreichung, neue Fertigungsprozess, Bio-Scaffolding, neueste Trends und Herausforderungen für 3D- und 4D-Bioprinting in der Biofabrikation. Dieses wertvolle Referenzwerk - ist ein umfassender Leitfaden zu 3D- und 4D-Drucktechniken in der Biomedizin und Pharmazie. - informiert u. a. über die erste 3D-Druckplattform mit FDA-Zulassung für ein pharmazeutisches Erzeugnis. - enthält Reviews der derzeit verfügbaren pharmazeutischen Erzeugnisse, die per 3D-Druck hergestellt wurden. - präsentiert die jüngsten Fortschritte bei neuartigen Materialien für den 3D- und 4D-Druck und biomedizinische Anwendungen.

Pharmakokinetik

Author : Erich Gladtke
ISBN : 9783662092729
Genre : Medical
File Size : 60. 37 MB
Format : PDF
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Die Herausgeber dieses Büchleins sind bzw. waren meine langjährigen Mitarbeiter und haben sich überwiegend mit der praktischen und ange wandten Pharmakokinetik beschäftigt. Aus der gemeinsamen Arbeit ergab sich, daß unsere Arbeitsgruppe immer wieder zu Fortbildungsvor trägen und Einführungskursen über das Gebiet der Pharmakokinetik gebeten wurde. Diese Veranstaltungen waren vor allem für jene gedacht, die sich bisher noch nicht mit der Pharmakokinetik beschäftigt hatten, die also wissen wollten, um was es sich bei dieser Materie überhaupt handelt. Beim ersten Hinsehen erscheinen manchem Mediziner und Biologen die Formulierungen und mathematischen Ableitungen, wie sie in einigen diesbezüglichen Arbeiten verwendet werden und wie ich sie in meinen Grundlagen der Pharmakokinetik ausführlich immer wieder bringen mußte, vielleicht zu kompliziert und zu abschreckend. Deshalb begrüße ich es, daß Herr Gladtke und Herr von Hattingberg bewegt werden konnten, den Inhalt dieser Kurse niederzuschreiben. Es soll eine Orientierung und Einführung sein. Sicher werden einige Leser dadurch angeregt, tiefer in jene Materie einzudringen, die ich seinerzeit (1953) Pharmakokinetik genannt habe, ohne zu wissen, daß diese Be zeichnung inzwischen weltweite Bedeutung erlangt haben würde. Damit wäre das Büchlein von Nutzen. Ich darf dies den Autoren wünschen. Gießen, Dezember 1972 F.H. DOST V Vorwort Diese Schrift ist als Einführung in die Pharmakokinetik gedacht und darf damit nicht als Lehrbuch, Nachschlagewerk oder erschöpfende Dar stellung verstanden werden. Der Vorsteher der Sektion antimikrobielle Chemotherapie der Paul Ehr lich-Gesellschaft und Leiter der Abteilung für antimikrobielle Therapie der Universitäts-Kinderklinik München, Herr Professor Dr. med.

Unser K Rper Unser Leben

Author : Kerstin Lorenzen
ISBN : OCLC:630437359
Genre :
File Size : 38. 5 MB
Format : PDF
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Theory And Practice Of Contemporary Pharmaceutics

Author : Tapash K. Ghosh
ISBN : 0203644476
Genre : Medical
File Size : 37. 6 MB
Format : PDF, Mobi
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With a shift toward problem-based learning and critical thinking in many health science fields, professional pharmacy training faces a shift in focus as well. Although the Accreditation Council for Pharmacy Education (ACPE) has recently suggested guidelines for problem solving to be better integrated into pharmacy curriculum, pharmacy books currently available either address this material inadequately or lack it completely. Theory and Practice of Contemporary Pharmaceutics addresses this problem by challenging pharmacy students to think critically in preparation for situations that arise in clinical practice. This book offers a wealth of up-to-date information, organized in a logical sequence, corresponding to the art and science required for formulators in industry and dispensing pharmacists in the community. It breaks down the subject to its simplest form and includes numerous examples, case studies, and problems. In addition to presenting basic scientific principles, each chapter includes a self-evaluation tutorial designed to help you evaluate your understanding of the subject matter, numerical problems that provide practice in finding mathematical solutions, and case studies that measure your overall grasp of the subject matter by challenging you to craft a plausible solution to a real-life scenario using the concepts presented in that chapter. Written by authors selected from academia, industry, and regulatory agencies, the book presents an objective and balanced view of pharmaceutical science and its application. The authors' insights are extremely helpful to pharmacy students as well as practicing pharmacists involved in the development and/or dispensation of existing and new generation biotechnology-based drug products. This simplified and user-friendly book will present pharmaceutics in a way that it has never been presented before and will help prepare students and pharmacists for the competitive and challenging nature of the professional market.

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