oral controlled release formulation design and drug delivery theory to practice

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Oral Controlled Release Formulation Design And Drug Delivery

Author : Hong Wen
ISBN : 1118060326
Genre : Science
File Size : 26. 44 MB
Format : PDF
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This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.

Developing Solid Oral Dosage Forms

Author : Yihong Qiu
ISBN : 9780128026373
Genre : Medical
File Size : 49. 19 MB
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Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. Chapters have been added, combined, deleted, and completely revised as necessary to produce a comprehensive, well-organized, valuable reference for industry professionals and academics engaged in all aspects of the development process. New and important topics include spray drying, amorphous solid dispersion using hot-melt extrusion, modeling and simulation, bioequivalence of complex modified-released dosage forms, biowaivers, and much more. Written and edited by an international team of leading experts with experience and knowledge across industry, academia, and regulatory settings Includes new chapters covering the pharmaceutical applications of surface phenomenon, predictive biopharmaceutics and pharmacokinetics, the development of formulations for drug discovery support, and much more Presents new case studies throughout, and a section completely devoted to regulatory aspects, including global product regulation and international perspectives

Engineering Polymer Systems For Improved Drug Delivery

Author : Rebecca A. Bader
ISBN : 9781118747803
Genre : Social Science
File Size : 62. 42 MB
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Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

Melt Extrusion

Author : Michael A. Repka
ISBN : 9781461484325
Genre : Medical
File Size : 87. 82 MB
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This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applications of a variety of extrusion processes, including various pharma grade extruders. In addition, the downstream production of films, pellets and tablets, for example, for oral and other delivery routes, are presented and discussed utilizing melt extrusion. This book is the first of its kind that discusses extensively the well-developed science of extrusion technology as applied to pharmaceutical drug product development and manufacturing. By covering a wide range of relevant topics, the text brings together all technical information necessary to develop and market pharmaceutical dosage forms that meet current quality and regulatory requirements. As extrusion technology continues to be refined further, usage of extruder systems and the array of applications will continue to expand, but the core technologies will remain the same.

Handbuch Der Vergleichenden Anatomie Der Haustiere

Author : Wilhelm Ellenberger
ISBN : 9783642808326
Genre : Science
File Size : 62. 3 MB
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Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

Theory And Practice Of Contemporary Pharmaceutics

Author : Tapash K. Ghosh
ISBN : 0203644476
Genre : Medical
File Size : 33. 76 MB
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With a shift toward problem-based learning and critical thinking in many health science fields, professional pharmacy training faces a shift in focus as well. Although the Accreditation Council for Pharmacy Education (ACPE) has recently suggested guidelines for problem solving to be better integrated into pharmacy curriculum, pharmacy books currently available either address this material inadequately or lack it completely. Theory and Practice of Contemporary Pharmaceutics addresses this problem by challenging pharmacy students to think critically in preparation for situations that arise in clinical practice. This book offers a wealth of up-to-date information, organized in a logical sequence, corresponding to the art and science required for formulators in industry and dispensing pharmacists in the community. It breaks down the subject to its simplest form and includes numerous examples, case studies, and problems. In addition to presenting basic scientific principles, each chapter includes a self-evaluation tutorial designed to help you evaluate your understanding of the subject matter, numerical problems that provide practice in finding mathematical solutions, and case studies that measure your overall grasp of the subject matter by challenging you to craft a plausible solution to a real-life scenario using the concepts presented in that chapter. Written by authors selected from academia, industry, and regulatory agencies, the book presents an objective and balanced view of pharmaceutical science and its application. The authors' insights are extremely helpful to pharmacy students as well as practicing pharmacists involved in the development and/or dispensation of existing and new generation biotechnology-based drug products. This simplified and user-friendly book will present pharmaceutics in a way that it has never been presented before and will help prepare students and pharmacists for the competitive and challenging nature of the professional market.

Pharmakokinetik

Author : Erich Gladtke
ISBN : 9783662092712
Genre : Medical
File Size : 65. 58 MB
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Sustained And Controlled Release Drug Delivery Systems

Author : Joseph R. Robinson
ISBN : UOM:39015006691334
Genre : Controlled release preparations
File Size : 38. 16 MB
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Pharmaceutical Formulation

Author : Geoffrey D Tovey
ISBN : 9781849739412
Genre :
File Size : 89. 30 MB
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Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development. Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.

Drug Metabolism Reviews

Author : Frederick J. DiCarlo
ISBN : IND:30000091408439
Genre : Drugs
File Size : 90. 60 MB
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