mouse brain development results and problems in cell differentiation

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Mouse Brain Development

Author : Andre M. Goffinet
ISBN : 9783540480020
Genre : Science
File Size : 67. 34 MB
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Our understanding of the molecular mechanisms involved in mammalian brain development remains limited. However, the last few years have wit nessed a quantum leap in our knowledge, due to technological improve ments, particularly in molecular genetics. Despite this progress, the available body of data remains mostly phenomenological and reveals very little about the grammar that organizes the molecular dictionary to articulate a pheno type. Nevertheless, the recent progress in genetics will allow us to contem plate, for the first time, the integration of observation into a coherent view of brain development. Clearly, this may be a major challenge for the next century, and arguably is the most important task of contemporary develop mental biology. The purpose of the present book is to provide an overview that syn thesizes up-to-date information on selected aspects of mouse brain devel opment. Given the format, it was not possible to cover all aspects of brain development, and many important subjects are missing. The selected themes are, to a certain extent, subjective and reflect the interests of the contributing authors. Examples of major themes that are not covered are peripheral nervous system development, including myelination, the development of the hippocampus and several other CNS structures, as well as the developmental function of some important morphoregulatory molecules.

The Human Central Nervous System

Author : Rudolf Nieuwenhuys
ISBN : 9783540346869
Genre : Medical
File Size : 79. 19 MB
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The present edition of The Human Central Nervous System differs considerably from its predecessors. In previous editions, the text was essentially confined to a section dealing with the various functional systems of the brain. This section, which has been rewritten and updated, is now preceded by 15 newly written chapters, which introduce the pictorial material of the gross anatomy, the blood vessels and meninges and the microstructure of its various parts and deal with the development, topography and functional anatomy of the spinal cord, the brain stem and the cerebellum, the diencephalon and the telencephalon. Great pains have been taken to cover the most recent concepts and data. As suggested by the front cover, there is a focus on the evolutionary development of the human brain. Throughout the text numerous correlations with neuropathology and clinical n- rology have been made. After much thought, we decided to replace the full Latin terminology, cherished in all previous editions, with English and Anglicized Latin terms. It has been an emotional farewell from beautiful terms such as decussatio hipposideriformis W- nekinkii and pontes grisei caudatolenticulares. Not only the text, but also the p- torial material has been extended and brought into harmony with the present state of knowledge. More than 230 new illustrations have been added and many others have been revised. The number of macroscopical sections through the brain has been extended considerably. Together, these illustrations now comprise a complete and convenient atlas for interpreting neuroimaging studies.

Results And Problems In Cell Differentiation

Author : W. Beermann
ISBN : UVA:X001448072
Genre : Cell differentiation
File Size : 51. 25 MB
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Molecular Chaperones And Folding Catalysts

Author : Bernd Bakau
ISBN : 9780203303757
Genre : Science
File Size : 51. 33 MB
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One of the most intriguing discoveries in molecular biology in the last decade is the existence of an evolutionary conserved and essential system, consisting of molecular chaperones and folding catalysts, which promotes the folding of the proteins in the cell. This text summarizes our current knowledge of the cellular roles, the regulation and the mechanism of action of this system. It has a broad scope, covering cell biological, genetic and biochemical aspects of protein folding in cells from bacteria to man. Particularly appropriate to researchers working in basic and applied aspects of molecular medicine, this volume should also prove useful as an up-to-date reference book and as a textbook for specialized university courses.

Cell Cycle In Development

Author : Jacek Z. Kubiak
ISBN : 3642190650
Genre : Science
File Size : 70. 4 MB
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This book focuses on the intersection between cell cycle regulation and embryo development. Specific modifications of the canonical cell cycle occur throughout the whole period of development and are adapted to fulfil functions coded by the developmental program. Deciphering these adaptations is essential to comprehending how living organisms develop. The aim of this book is to review the best-known modifications and adaptations of the cell cycle during development. The first chapters cover the general problems of how the cell cycle evolves, while consecutive chapters guide readers through the plethora of such phenomena. The book closes with a description of specific changes in the cell cycle of neurons in the senescent human brain. Taken together, the chapters present a panorama of species - from worms to humans - and of developmental stages - from unfertilized oocyte to aged adult.

Journal Of Cell Science

Author :
ISBN : UOM:39015053943794
Genre : Cytology
File Size : 73. 87 MB
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Oxford Textbook Of Old Age Psychiatry

Author : Robin Jacoby
ISBN : IND:30000110550641
Genre : Medical
File Size : 63. 96 MB
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The Oxford Textbook of Old Age Psychiatry is the new edition of the much loved and highly popular multi-author textbook previously published as Psychiatry in the Elderly. It has established itself as the standard textbook in its field due to its unique combination of comprehensive coverage, clear writing and authoritative and up-to-date information. This new edition maintains these strengths, with chapters covering the basic sciences underpinning old agepsychiatry, clinical practice, psychiatric services for older people, specific disorders and medico-legal and ethical issues.The text has been extensively updated, with several new chapters added reflecting developments in the speciality. These include chapters on: different psychotherapies, e.g. interpersonal therapy and cognitive behavioural therapy, and electroconvulsive therapy; memory clinics and liaison old age psychiatry; mild cognitive impairment and sleep disorders; and chapters by patients reflecting their experiences of their illnesses. The textbook has expanded to include 73 contributors from 8 differentcountries covering the panoply of relevant expertise. The editorial team has also grown with Robin Jacoby and Catherine Oppenheimer now being joined by Tom Dening and Alan Thomas.The breadth of authoritative coverage will continue to make this book one which all old age psychiatrists and trainees will want to have on their bookshelves. Geriatricians and other health professionals working with older people will also find in this book a handy resource to assist them when dealing with psychiatric disorders in older people.

Sex Chromosome Disorders Advances In Research And Treatment 2012 Edition

Author :
ISBN : 9781481618915
Genre : Medical
File Size : 69. 18 MB
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Sex Chromosome Disorders—Advances in Research and Treatment: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Sex Chromosome Disorders in a concise format. The editors have built Sex Chromosome Disorders—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Sex Chromosome Disorders in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Sex Chromosome Disorders—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at

Vertebrate Eye Development

Author : M. Elizabeth Fini
ISBN : 9783540468264
Genre : Science
File Size : 21. 2 MB
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"Who would believe that so small a space could contain the images of all the universe?" Leonardo da Vinci The last years of the 20th century have found the discipline of Developmental Biology returning to its original position at the forefront of biological re search. This progress can be attributed to the burgeoning knowledge base on molecules and gene families, and to the power of the molecular genetic ap proach. Topping the list of organ systems which have provided the most significant advances would have to be the eye. The vertebrate eye was one of the classic embryologic models, used to demonstrate many important prin ciples, including the concepts of inductive tissue interactions first put forth in the early 1900s. Within the last decade of this century, a return to some of the old questions with the new approaches has put eye development back into the limelight. I find this a highly appropriate topic for a book which aims to spark research for the new millennium. We begin with a chapter that discusses the anatomy of eye development, providing the basic reference information for the chapters that follow. A novel aspect of this introduction is the connection made between develop mental strategies and the eye's optical function. What also emerges from this chapter is the number of important eye structures that have barely been touched by the modern developmental biologist. Work on cornea and ante rior chamber development has lagged behind lens and retina.

Subject Guide To Books In Print

Author :
ISBN : STANFORD:36105025888517
Genre : American literature
File Size : 42. 5 MB
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