modelling survival data in medical research third edition chapman hall crc texts in statistical science

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Modelling Survival Data In Medical Research Third Edition

Author : David Collett
ISBN : 9781498731690
Genre : Mathematics
File Size : 59. 18 MB
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Modelling Survival Data in Medical Research describes the modelling approach to the analysis of survival data using a wide range of examples from biomedical research. Well known for its nontechnical style, this third edition contains new chapters on frailty models and their applications, competing risks, non-proportional hazards, and dependent censoring. It also describes techniques for modelling the occurrence of multiple events and event history analysis. Earlier chapters are now expanded to include new material on a number of topics, including measures of predictive ability and flexible parametric models. Many new data sets and examples are included to illustrate how these techniques are used in modelling survival data. Bibliographic notes and suggestions for further reading are provided at the end of each chapter. Additional data sets to obtain a fuller appreciation of the methodology, or to be used as student exercises, are provided in the appendix. All data sets used in this book are also available in electronic format online. This book is an invaluable resource for statisticians in the pharmaceutical industry, professionals in medical research institutes, scientists and clinicians who are analyzing their own data, and students taking undergraduate or postgraduate courses in survival analysis.

Modelling Survival Data In Medical Research Second Edition

Author : David Collett
ISBN : 9781584883258
Genre : Mathematics
File Size : 64. 64 MB
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Critically acclaimed and resoundingly popular in its first edition, Modelling Survival Data in Medical Research has been thoroughly revised and updated to reflect the many developments and advances--particularly in software--made in the field over the last 10 years. Now, more than ever, it provides an outstanding text for upper-level and graduate courses in survival analysis, biostatistics, and time-to-event analysis.The treatment begins with an introduction to survival analysis and a description of four studies that lead to survival data. Subsequent chapters then use those data sets and others to illustrate the various analytical techniques applicable to such data, including the Cox regression model, the Weibull proportional hazards model, and others. This edition features a more detailed treatment of topics such as parametric models, accelerated failure time models, and analysis of interval-censored data. The author also focuses the software section on the use of SAS, summarising the methods used by the software to generate its output and examining that output in detail. Profusely illustrated with examples and written in the author's trademark, easy-to-follow style, Modelling Survival Data in Medical Research, Second Edition is a thorough, practical guide to survival analysis that reflects current statistical practices.

Multivariate Survival Analysis And Competing Risks

Author : Martin J. Crowder
ISBN : 9781439875223
Genre : Mathematics
File Size : 29. 31 MB
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Multivariate Survival Analysis and Competing Risks introduces univariate survival analysis and extends it to the multivariate case. It covers competing risks and counting processes and provides many real-world examples, exercises, and R code. The text discusses survival data, survival distributions, frailty models, parametric methods, multivariate data and distributions, copulas, continuous failure, parametric likelihood inference, and non- and semi-parametric methods. There are many books covering survival analysis, but very few that cover the multivariate case in any depth. Written for a graduate-level audience in statistics/biostatistics, this book includes practical exercises and R code for the examples. The author is renowned for his clear writing style, and this book continues that trend. It is an excellent reference for graduate students and researchers looking for grounding in this burgeoning field of research.

Dynamic Prediction In Clinical Survival Analysis

Author : Hans van Houwelingen
ISBN : 9781439835432
Genre : Mathematics
File Size : 81. 75 MB
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There is a huge amount of literature on statistical models for the prediction of survival after diagnosis of a wide range of diseases like cancer, cardiovascular disease, and chronic kidney disease. Current practice is to use prediction models based on the Cox proportional hazards model and to present those as static models for remaining lifetime after diagnosis or treatment. In contrast, Dynamic Prediction in Clinical Survival Analysis focuses on dynamic models for the remaining lifetime at later points in time, for instance using landmark models. Designed to be useful to applied statisticians and clinical epidemiologists, each chapter in the book has a practical focus on the issues of working with real life data. Chapters conclude with additional material either on the interpretation of the models, alternative models, or theoretical background. The book consists of four parts: Part I deals with prognostic models for survival data using (clinical) information available at baseline, based on the Cox model Part II is about prognostic models for survival data using (clinical) information available at baseline, when the proportional hazards assumption of the Cox model is violated Part III is dedicated to the use of time-dependent information in dynamic prediction Part IV explores dynamic prediction models for survival data using genomic data Dynamic Prediction in Clinical Survival Analysis summarizes cutting-edge research on the dynamic use of predictive models with traditional and new approaches. Aimed at applied statisticians who actively analyze clinical data in collaboration with clinicians, the analyses of the different data sets throughout the book demonstrate how predictive models can be obtained from proper data sets.

Handbook Of Survival Analysis

Author : John P. Klein
ISBN : 9781466555679
Genre : Mathematics
File Size : 20. 10 MB
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Handbook of Survival Analysis presents modern techniques and research problems in lifetime data analysis. This area of statistics deals with time-to-event data that is complicated by censoring and the dynamic nature of events occurring in time. With chapters written by leading researchers in the field, the handbook focuses on advances in survival analysis techniques, covering classical and Bayesian approaches. It gives a complete overview of the current status of survival analysis and should inspire further research in the field. Accessible to a wide range of readers, the book provides: An introduction to various areas in survival analysis for graduate students and novices A reference to modern investigations into survival analysis for more established researchers A text or supplement for a second or advanced course in survival analysis A useful guide to statistical methods for analyzing survival data experiments for practicing statisticians

Design And Analysis Of Clinical Trials

Author : Shein-Chung Chow
ISBN : 9780471473299
Genre : Mathematics
File Size : 85. 49 MB
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Epidemiology

Author : Mark Woodward
ISBN : 9781482243208
Genre : Mathematics
File Size : 37. 57 MB
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Highly praised for its broad, practical coverage, the second edition of this popular text incorporated the major statistical models and issues relevant to epidemiological studies. Epidemiology: Study Design and Data Analysis, Third Edition continues to focus on the quantitative aspects of epidemiological research. Updated and expanded, this edition shows students how statistical principles and techniques can help solve epidemiological problems. New to the Third Edition New chapter on risk scores and clinical decision rules New chapter on computer-intensive methods, including the bootstrap, permutation tests, and missing value imputation New sections on binomial regression models, competing risk, information criteria, propensity scoring, and splines Many more exercises and examples using both Stata and SAS More than 60 new figures After introducing study design and reviewing all the standard methods, this self-contained book takes students through analytical methods for both general and specific epidemiological study designs, including cohort, case-control, and intervention studies. In addition to classical methods, it now covers modern methods that exploit the enormous power of contemporary computers. The book also addresses the problem of determining the appropriate size for a study, discusses statistical modeling in epidemiology, covers methods for comparing and summarizing the evidence from several studies, and explains how to use statistical models in risk forecasting and assessing new biomarkers. The author illustrates the techniques with numerous real-world examples and interprets results in a practical way. He also includes an extensive list of references for further reading along with exercises to reinforce understanding. Web Resource A wealth of supporting material can be downloaded from the book’s CRC Press web page, including: Real-life data sets used in the text SAS and Stata programs used for examples in the text SAS and Stata programs for special techniques covered Sample size spreadsheet

Modelling Survival Data In Medical Research Second Edition

Author : David Collett
ISBN : 9781584883258
Genre : Mathematics
File Size : 67. 47 MB
Format : PDF, Mobi
Download : 490
Read : 545

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Critically acclaimed and resoundingly popular in its first edition, Modelling Survival Data in Medical Research has been thoroughly revised and updated to reflect the many developments and advances--particularly in software--made in the field over the last 10 years. Now, more than ever, it provides an outstanding text for upper-level and graduate courses in survival analysis, biostatistics, and time-to-event analysis.The treatment begins with an introduction to survival analysis and a description of four studies that lead to survival data. Subsequent chapters then use those data sets and others to illustrate the various analytical techniques applicable to such data, including the Cox regression model, the Weibull proportional hazards model, and others. This edition features a more detailed treatment of topics such as parametric models, accelerated failure time models, and analysis of interval-censored data. The author also focuses the software section on the use of SAS, summarising the methods used by the software to generate its output and examining that output in detail. Profusely illustrated with examples and written in the author's trademark, easy-to-follow style, Modelling Survival Data in Medical Research, Second Edition is a thorough, practical guide to survival analysis that reflects current statistical practices.

Modeling Survival Data Extending The Cox Model

Author : Terry M. Therneau
ISBN : 9781475732948
Genre : Mathematics
File Size : 87. 19 MB
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This book is for statistical practitioners, particularly those who design and analyze studies for survival and event history data. Building on recent developments motivated by counting process and martingale theory, it shows the reader how to extend the Cox model to analyze multiple/correlated event data using marginal and random effects. The focus is on actual data examples, the analysis and interpretation of results, and computation. The book shows how these new methods can be implemented in SAS and S-Plus, including computer code, worked examples, and data sets.

Statistical Methods For Survival Data Analysis

Author : Elisa T. Lee
ISBN : 9781118593059
Genre : Mathematics
File Size : 21. 60 MB
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Praise for the Third Edition “. . . an easy-to read introduction to survival analysis which covers the major concepts and techniques of the subject.” —Statistics in Medical Research Updated and expanded to reflect the latest developments, Statistical Methods for Survival Data Analysis, Fourth Edition continues to deliver a comprehensive introduction to the most commonly-used methods for analyzing survival data. Authored by a uniquely well-qualified author team, the Fourth Edition is a critically acclaimed guide to statistical methods with applications in clinical trials, epidemiology, areas of business, and the social sciences. The book features many real-world examples to illustrate applications within these various fields, although special consideration is given to the study of survival data in biomedical sciences. Emphasizing the latest research and providing the most up-to-date information regarding software applications in the field, Statistical Methods for Survival Data Analysis, Fourth Edition also includes: Marginal and random effect models for analyzing correlated censored or uncensored data Multiple types of two-sample and K-sample comparison analysis Updated treatment of parametric methods for regression model fitting with a new focus on accelerated failure time models Expanded coverage of the Cox proportional hazards model Exercises at the end of each chapter to deepen knowledge of the presented material Statistical Methods for Survival Data Analysis is an ideal text for upper-undergraduate and graduate-level courses on survival data analysis. The book is also an excellent resource for biomedical investigators, statisticians, and epidemiologists, as well as researchers in every field in which the analysis of survival data plays a role.

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