microbial based polyhydroxyalkanoates upstream and downstream processing

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Microbial Based Polyhydroxyalkanoates

Author : Amirul Al-Ashraf Abdullah
ISBN : 9781909030640
Genre : Science
File Size : 82. 85 MB
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Polyhydroxyalkanoate (PHA) is a group of natural biopolymers synthesised by a wide variety of microbial genera. It is a biodegradable and biocompatible thermoplastic consisting of a repeated chain of various hydroxyalkanoate monomers.PHA is envisioned to be one of the most prospective and futuristic materials which is beneficial to mankind and to the world. In current world trends which concerns at the sustainable development from renewable and eco-friendly resources, PHA has garnered a growing attention as an alternative to petroleum based plastics.The book comes with two main objectives. In this book, major pipelines in processing this beneficial biopolymer were first reviewed from upstream to the downstream. The upstream processing includes the isolation of PHA producers, biosynthesis of PHA, genetic modification of PHA producers and optimisation of PHA production; meanwhile the downstream processing covers the PHA recovery and purification, degradation, quantification, characterisation, as well as the application of PHA. Readers will be exposed to the introductory information, along with some necessary concepts behind each subject.The second objective of this book is to provide readers with the recent advances on each PHA processing field. Being updated with the recent findings, this will provide an insight to readers on how the research trends for each subject are evolving from time to time. These updates will become useful case studies and quick references to readers from various areas, either from academia or industry.

Advances In Polyhydroxyalkanoate Pha Production

Author : Martin Koller
ISBN : 9783038426370
Genre : Science
File Size : 68. 51 MB
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This book is a printed edition of the Special Issue "Advances in Polyhydroxyalkanoate (PHA) Production" that was published in Bioengineering

Recent Advances In Biotechnology Volume 1 Microbial Biopolyester Production Performance And Processing Microbiology Feedstocks And Metabolism

Author : Martin Koller
ISBN : 9781681083254
Genre : Science
File Size : 60. 69 MB
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Global plastic production is estimated to be over 300Mt annually. Most conventional plastics are predominantly produced from fossil fuels and are highly resistant to biodegradation, and only a small share of about 20% of spent plastics is believed to be recycled, which is a cause for environmental concern. Biodegradable plastics would solve this concern as they are a sustainable alternative, yet these do not even cover 5% of the global plastic market. Microbial polyhydroxyalkanoates (PHAs) are a versatile group of polyesters produced by nature as prokaryotic storage materials. PHAs can be produced through sustainable bioprocess engineering and have displayed remarkable flexibility in their physical and chemical properties. PHAs are the subject of several scientific papers and numerous PHA patents have also been filed, generating significant interest in the plastic production industry. To develop overall sustainable and efficient production processes, all bioprocess steps need to be thoroughly understood and accounted for. These processes start with the selection of suitable inexpensive raw materials (microbes and enzymes), optimizing the process engineering and process regime, and conclude with the enhancement of product recovery in terms of time, energy, and material input. Microbial Biopolyester Production, Performance and Processing: Microbiology, Feedstocks, and Metabolism encompasses eight chapters that cover aspects of the microbiology and biotechnology of producing biodegradable plastics. The contents focus on the selection of powerful archaeal and eubacterial production strains, genetic engineering as a tool for optimized PHA production and inexpensive carbon sources for microbial cultures. The volume is a useful resource for bioprocess engineers, microbiologists, biotechnologists and chemical engineers interested in the basics of biodegradable plastic production. Recent Advances in Biotechnology is a book series comprising of peer-reviewed reference works and monographs that compile the latest developments in the field of biotechnology. Each volume has a thematic focus and features topical reviews written by experts. The series will highlight multidisciplinary perspectives to interested readers (biotechnologists, microbiologists, bioprocess engineers, agronomists, medical professionals, sustainability researchers etc.)

Recent Advances In Biotechnology Volume 2 Microbial Biopolyester Production Performance And Processing Bioengineering Characterization And Sustainability

Author : Martin Koller
ISBN : 9781681083735
Genre : Science
File Size : 57. 17 MB
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Global plastic production is estimated to be over 300Mt annually. Most conventional plastics are predominantly produced from fossil fuels and are highly resistant to biodegradation, and only a small share of about 20% of spent plastics is believed to be recycled, which is a cause for environmental concern. Biodegradable plastics would solve this concern as they are a sustainable alternative, yet these do not even cover 5% of the global plastic market. Microbial polyhydroxyalkanoates (PHAs) are a versatile group of polyesters produced by nature as prokaryotic storage materials. PHAs can be produced through sustainable bioprocess engineering and have displayed remarkable flexibility in their physical and chemical properties. PHAs are the subject of several scientific papers and numerous PHA patents have also been filed, generating significant interest in the plastic production industry. To develop overall sustainable and efficient production processes, all bioprocess steps need to be thoroughly understood and accounted for. These processes start with the selection of suitable inexpensive raw materials (microbes and enzymes), optimizing the process engineering and process regime, and conclude with the enhancement of product recovery in terms of time, energy, and material input. Microbial Biopolyester Production, Performance and Processing: Bioengineering, Characterization, and Sustainability is a compilation of eight chapters covering bacterial polyesters, green plastics and PHAs from various angles. The contents of this volume focus on sustainable practices focus on the sustainability of processes that involve the synthesis and recycling of these meterials. The volume is a useful resource for bioprocess engineers, microbiologists, biotechnologists and chemical engineers interested in the basics of biodegradable plastic production.

Technology And Applications Of Polymers Derived From Biomass

Author : Syed Ali Ashter
ISBN : 9780323511162
Genre : Technology & Engineering
File Size : 83. 80 MB
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Technology and Applications of Polymers Derived from Biomass explores the range of different possible routes from biomass to polymeric materials, including the value and limitations of using biomass in material applications and a comparison of petrochemical-derived polymers and bio-based polymers. The book discusses biomass sources, types, chemistry and handling concerns. It covers the manufacture of industrial chemicals from biomass and the derivation of monomers and polymers from biomass. It also details the processing and applications of biomass-derived polymers to enable materials scientists and engineers realize the potential of biomass as a sustainable source of polymers, including plastics and elastomers. The book is a one-stop-shop reference—giving students a basic understanding of the technology and how the material can be applied to industrial processes they will face in the workforce, and giving materials engineers and product designers the information they need to make more informed material selection decisions. Provides fundamental understanding of an increasingly important approach to sourcing polymeric materials Includes actionable, relevant information to enable materials engineers and product designers consider biomass-derived polymers in the products they are developing Discusses the environmental impact of biomass conversion to help readers improve the sustainability of their operations Compares petrochemical-derived polymers with bio-based polymers

Advances In Polyhydroxyalkanoate Pha Production

Author : Martin Koller
ISBN : 9783038426370
Genre : Science
File Size : 58. 53 MB
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This book is a printed edition of the Special Issue "Advances in Polyhydroxyalkanoate (PHA) Production" that was published in Bioengineering

Comprehensive Biotechnology

Author :
ISBN : 9780080885049
Genre : Science
File Size : 57. 60 MB
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The second edition of Comprehensive Biotechnology continues the tradition of the first inclusive work on this dynamic field with up-to-date and essential entries on the principles and practice of biotechnology. The integration of the latest relevant science and industry practice with fundamental biotechnology concepts is presented with entries from internationally recognized world leaders in their given fields. With two volumes covering basic fundamentals, and four volumes of applications, from environmental biotechnology and safety to medical biotechnology and healthcare, this work serves the needs of newcomers as well as established experts combining the latest relevant science and industry practice in a manageable format. It is a multi-authored work, written by experts and vetted by a prestigious advisory board and group of volume editors who are biotechnology innovators and educators with international influence. All six volumes are published at the same time, not as a series; this is not a conventional encyclopedia but a symbiotic integration of brief articles on established topics and longer chapters on new emerging areas. Hyperlinks provide sources of extensive additional related information; material authored and edited by world-renown experts in all aspects of the broad multidisciplinary field of biotechnology Scope and nature of the work are vetted by a prestigious International Advisory Board including three Nobel laureates Each article carries a glossary and a professional summary of the authors indicating their appropriate credentials An extensive index for the entire publication gives a complete list of the many topics treated in the increasingly expanding field

Plastics From Bacteria

Author : George Guo-Qiang Chen
ISBN : 3642032877
Genre : Science
File Size : 86. 26 MB
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Due to the possibility that petroleum supplies will be exhausted in the next decades to come, more and more attention has been paid to the production of bacterial pl- tics including polyhydroxyalkanoates (PHA), polylactic acid (PLA), poly(butylene succinate) (PBS), biopolyethylene (PE), poly(trimethylene terephthalate) (PTT), and poly(p-phenylene) (PPP). These are well-studied polymers containing at least one monomer synthesized via bacterial transformation. Among them, PHA, PLA and PBS are well known for their biodegradability, whereas PE, PTT and PPP are probably less biodegradable or are less studied in terms of their biodegradability. Over the past years, their properties and appli- tions have been studied in detail and products have been developed. Physical and chemical modifications to reduce their cost or to improve their properties have been conducted. PHA is the only biopolyester family completely synthesized by biological means. They have been investigated by microbiologists, molecular biologists, b- chemists, chemical engineers, chemists, polymer experts, and medical researchers for many years. PHA applications as bioplastics, fine chemicals, implant biomate- als, medicines, and biofuels have been developed. Companies have been est- lished for or involved in PHA related R&D as well as large scale production. It has become clear that PHA and its related technologies form an industrial value chain in fermentation, materials, feeds, and energy to medical fields.

Bioprocessing For Value Added Products From Renewable Resources

Author : Shang-Tian Yang
ISBN : 0080466710
Genre : Technology & Engineering
File Size : 66. 46 MB
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Bioprocessing for Value-Added Products from Renewable Resources provides a timely review of new and unconventional techniques for manufacturing high-value products based on simple biological material. The book discusses the principles underpinning modern industrial biotechnology and describes a unique collection of novel bioprocesses for a sustainable future. This book begins in a very structured way. It first looks at the modern technologies that form the basis for creating a bio-based industry before describing the various organisms that are suitable for bioprocessing - from bacteria to algae - as well as their unique characteristics. This is followed by a discussion of novel, experimental bioprocesses, such as the production of medicinal chemicals, the production of chiral compounds and the design of biofuel cells. The book concludes with examples where biological, renewable resources become an important feedstock for large-scale industrial production. This book is suitable for researchers, practitioners, students, and consultants in the bioprocess and biotechnology fields, and for others who are interested in biotechnology, engineering, industrial microbiology and chemical engineering. ·Reviews the principles underpinning modern industrial biotechnology ·Provides a unique collection of novel bioprocesses for a sustainable future ·Gives examples of economical use of renewable resources as feedstocks ·Suitable for both non-experts and experts in the bioproduct industry

Process Scale Purification Of Antibodies

Author : Uwe Gottschalk
ISBN : 9781119126911
Genre : Medical
File Size : 77. 82 MB
Format : PDF
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Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier technology experts to address the challenges of antibody purification. • Updates existing topics and adds new ones that include purification of antibodies produced in novel production systems, novel separation technologies, novel antibody formats and alternative scaffolds, and strategies for ton-scale manufacturing • Presents new and updated discussions of different purification technologies, focusing on how they can address the capacity crunch in antibody purification • Emphasizes antibodies and innovative chromatography methods for processing

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