listeria monocytogenes pathogenesis and host response

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Listeria Monocytogenes Pathogenesis And Host Response

Author : Howard Goldfine
ISBN : 9780387493763
Genre : Science
File Size : 73. 24 MB
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During the past twenty years Listeria monocytogenes has emerged as one of the most intensely studied bacterial pathogens. New windows are constantly being opened into the complexity of host cell biology and the interplay of the signals connecting the various cells and organs involved in the host response. This volume includes research from studies at the molecular level on the pathogenesis of Listeria monocytogenes and the response of the host to its infections.

Human Emerging And Re Emerging Infections Set

Author : Sunit K. Singh
ISBN : 9781118644713
Genre : Science
File Size : 71. 76 MB
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Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases. • Covers emerging and re-emerging viral, parasitic, fungal, and bacterial infections • Includes detailed descriptions of diagnostic tools used in pathogen detection • Points the way forward for new diagnostic tools for emerging and re-emerging infections • Encompasses a variety of diagnostic techniques including cell cultures, animal inoculation, cultivation in artificial media, histopathological evaluation of tissues, serological techniques using surrogate antigens and advanced molecular biology based approaches • An invaluable resource for clinicians, instructors, basic and applied scientists, students, and established researchers

Foodborne Microbial Pathogens

Author : Arun Bhunia
ISBN : 9780387745374
Genre : Technology & Engineering
File Size : 82. 65 MB
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At last, here is a graduate-level textbook that focuses on the very latest information on the molecular and cellular mechanism of several major foodborne bacterial pathogens. For the first time in the field, this book makes the link between foodborne illness and immunology. It also covers virulence genes and their regulation in the host or the food environment, pathogenicity testing models, clinical symptoms and prevention and control strategies. Unlike other textbooks this one also covers the host/parasite interaction to a level where readers have a real appreciation of the disease mechanism. It is imperative that we acquire a better understanding of foodborne pathogens. And this is what this brilliant and timely contribution to the subject offers.

Handbook Of Listeria Monocytogenes

Author : Dongyou Liu
ISBN : 1420051415
Genre : Science
File Size : 20. 90 MB
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Once feared as a deadly intracellular bacterium with the extraordinary capacity to survive a wide array of arduous external stressors, Listeria monocytogenes is increasingly recognized as a preferred vector for delivering anti-infective and anti-cancer vaccine molecules. A reliable, single-source reference on the fundamental aspects of this bacterium is crucial to support future study and further the advancement of biomedical sciences and intervention strategies. Drawn from an international panel of scientists with notable expertise in their respective fields, the Handbook of Listeria monocytogenes is divided into four sections: Section I discusses the biology and pathogenicity of this bacterium, including epidemiology and stress responses. Section II demonstrates identification and detection techniques such as phenotypic and genotypic identification, strain typing, and virulence determination. Section III details the current knowledge of genetic manipulation of Listeria, including comparative genomics, genomic divisions, epidemic clones and population structure, and analysis of cell envelope proteins. Section IV covers innate and adaptive immunity against Listeria, and examines the use of this bacterium for anti-infective and anti-cancer vaccine development. The first comprehensive compilation of knowledge in this area, this handbook is an indispensable reference for anyone embarking on the path of manipulation of Listeria as either a model for the study of the host-bacterium relationship or as a tool for delivering protective molecules to cytoplasm.

Bacterial Pathogenesis

Author : Virginia L. Clark
ISBN : 0121821374
Genre : Science
File Size : 79. 72 MB
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This volume of Methods in Enzymology contains contributions covering the wide spectrum of interactions between bacterial pathogens and their eukaryotic hosts. It complements Volume 235, in which methods for the isolation and identification of bacterial pathogens and associated virulence determinants are described. Since the study of bacterial pathogenesis borrows from a great variety of technologies and disciplines, we aim to provide the reader with a representative sample of the most advanced pathogenesis research.

Bacterial Infections Of Humans

Author : Alfred S. Evans
ISBN : 9781461553274
Genre : Medical
File Size : 84. 90 MB
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In Memoriam of Alfred S. Evans This third edition of Bacterial Infections of Humans is dedicated to Alfred Spring Evans, who died on January 21, 1996, 2Yz years after a diagnosis of cancer. Al was the senior editor of this textbook, which he founded with Harry Feldman in 1982. Al was a clinician, epidemiologist, educator, catalyst for biomedical research, historian, author, speaker, seeker of the truth, sincere friend of students, sports enthusiast, traveler, and truly a man of all seasons. He was a devoted husband to Brigette Klug Evans, father of three children, and grandfather of four. Al was born in Buffalo, New York, on August 21,1917, to Ellen Spring and John H. Evans, M.D., one ofthe United States's first anesthesiologists and an early researcher in the field of oxygen therapy. He received his undergraduate training at the University of Michigan; was awarded an M.D. degree in 1943 from the University of Buffalo; interned in Pittsburgh, Pennsylvania; and performed his medical residency at the Goldwater Hospital in New York City. He was in the United States Army from 1944 to 1946, assigned as a public health officer to a base in Okinawa, Japan. It was there that he met Drs.

The Role Of Peptidoglycan Acetylation Of Listeria Monocytogenes In Pathogenesis And Innate Immunity

Author : Aimee Lynn Geissler
ISBN : UCAL:C3482743
Genre :
File Size : 35. 85 MB
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Case Studies In Infectious Disease Listeria Monocytogenes

Author : Peter Lydyard
ISBN : 9781136986550
Genre : Medical
File Size : 87. 80 MB
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Case Studies in Infectious Disease: Listeria monocytogenes presents the natural history of this infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis, and treatment. A set of core questions explores the nature, causation, host response, manifestations, and management of this infectious process. This case also includes summary bullet points, questions and answers, and references.

Infectious Diseases Of The Fetus And Newborn E Book

Author : Christopher B. Wilson
ISBN : 9781437736373
Genre : Medical
File Size : 21. 64 MB
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Infectious Diseases of the Fetus and Newborn Infant, written and edited by Drs. Remington, Klein, Wilson, Nizet, and Maldonado, remains the definitive source of information in this field. The 7th edition of this authoritative reference provides the most up-to-date and complete guidance on infections found in utero, during delivery, and in the neonatal period in both premature and term infants. Special attention is given to the prevention and treatment of these diseases found in developing countries as well as the latest findings about new antimicrobial agents, gram-negative infections and their management, and recommendations for immunization of the fetus/mother. Nationally and internationally recognized in immunology and infectious diseases, new associate editors Nizet and Maldonado bring new insight and fresh perspective to the book. Get the latest information on maternal infections when they are pertinent to the infant or developing fetus, including disease transmission through breastfeeding Diagnose, prevent, and treat neonatal infectious diseases with expert guidance from the world's leading authorities and evidence-based recommendations. Incorporate the latest findings about infections found in utero, during delivery, and in the neonatal period. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format Get fresh perspectives from two new associate editors—Drs. Yvonne Maldonado, head of the Pediatric Infectious Disease program at Stanford, and Victor Nizet, Professor of Pediatrics & Pharmacy at University of California, San Diego and UCSD School of Medicine. Keep up with the most relevant topics in fetal/neonatal infectious disease including new antimicrobial agents, gram- negative infections and their management, and recommendations for immunization of the fetus/mother. Overcome the clinical challenges in developing countries where access to proper medical care is limited. Apply the latest recommendations for H1N1 virus and vaccines. Identify and treat infections with the latest evidence-based information on fighting life-threatening diseases in the fetus and newborn infants.

Davidson S Principles And Practice Of Medicine

Author : Brian R. Walker
ISBN : 9780702051036
Genre : Medical
File Size : 49. 6 MB
Format : PDF
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More than two million medical students, doctors and other health professionals from around the globe have owned a copy of Davidson’s Principles and Practice of Medicine since it was first published. Today’s readers rely on this beautifully illustrated text to provide up-to-date detail of contemporary medical practice, presented in a style that is concise and yet easy to read. Davidson’s provides the factual knowledge required to practise medicine, explaining it in the context of underlying principles, basic science and research evidence, and shows how to apply this knowledge to the management of patients who present with problems rather than specific diseases. The book has won numerous prizes including being highly commended in the British Medical Association book awards. Davidson’s global perspective is enhanced by the input of an international team of authors and a distinguished International Advisory Board from 17 countries. Building on the foundations laid down by its original editor, Davidson’s remains one of the world’s leading and most respected textbooks of medicine. The underlying principles of medicine are described concisely in the first part of the book, and the detailed practice of medicine within each sub-specialty is described in later system-based chapters. Most chapters begin with a two-page overview of the important elements of the clinical examination, including a manikin to illustrate the key steps in the examination of the relevant system. A practical, problem-based clinical approach is described in the ‘Presenting Problems’ sections, to complement the detailed descriptions of each disease. The text is extensively illustrated, with over 1000 diagrams, clinical photographs, and radiology and pathology images. 1350 text boxes present information in a way suitable for revision, including 150 clinical evidence boxes summarising the results of systematic reviews and randomised controlled trials and 65 ’In Old Age’ boxes highlighting important aspects of medical practice in the older population. A combined index and glossary of medical acronyms contains over 10 000 subject entries. The contents can also be searched comprehensively as part of the online access to the whole book on the StudentConsult platform. Access over 500 self-testing questions with answers linked to the book’s content for further reading. The text uses both SI and non-SI units to make it suitable for readers throughout the globe. A new chapter specifically on Stroke Disease recognises the emergence of Stroke Medicine as a distinct clinical and academic discipline. A rationalisation of the 1350 boxes used throughout the book gives a simpler and clearer presentation of the various categories. New ‘In Adolescence’ boxes recognise the fact that many chronic disorders begin in childhood and become the responsibility of physicians practising adult medicine. These boxes acknowledge the overlap ‘transitional’ phase and highlight the key points of importance when looking after young people. The regular introduction of new authors and editors maintains the freshness of each new edition. On this occasion Dr Ian Penman has joined the editorial team and 18 new authors bring new experience and ideas to the content and presentation of the textbook. An expanded International Advisory Board of 38 members includes new members from several different countries.

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