lectins and cancer

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Lectins And Cancer

Author : Hans-Joachim Gabius
ISBN : 9783642767395
Genre : Medical
File Size : 89. 37 MB
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Molecular recognition undoubtedly governs any aspect of cellular interaction. To understand tumor cell growth regulation and spread, analysisof protein carbohydrate interactions can contribute to lead to the establishment of rational methods for diagnosis and therapy. Chemically and biochemically optimized preparation of adequate tools, their application for localization of receptor (tissue lectin) and ligand (cellular glycoconjugate) pairs in tumor cells and tumor sections and the usefulness of a lectin from a plant extract as potent immunomodulator indicate the prospect for a place of such techniques in pathology and oncology.

Lectins

Author : Arpad Pusztai
ISBN : 9780203983751
Genre : Medical
File Size : 83. 32 MB
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Lectins form a ubiquitous and important class of natural carbohydrate- binding information proteins. Although the main scientific interest was originally focussed on toxic lectins such as ricin, recent emphasis has shifted to exploring their involvement in cell-to-cell communication and recognition in microorganisms, plants and animals.; As knowledge of the basic properties and biological activities of lectins has increased, exciting opportunities have arisen for the exploitation of some of the advantageous aspects of fundamental lectinology.; "Lectins: Biomedical Perspectives" records the major achievements of an initiative, funded by the European Community, to coordinate lectin research throughout Europe.

Breast Cancer Research Protocols

Author : Susan A. Brooks
ISBN : 9781592599691
Genre : Medical
File Size : 64. 31 MB
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Leading cancer researchers have assembled the most significant research protocols used by scientists in breast cancer research today. These step-by-step techniquest can be utilized to accomplish numerous scientific studies in the race to find a cure for breast cancer.

B Ses Gem Se

Author : Steven R. Gundry
ISBN : 3407865120
Genre :
File Size : 72. 21 MB
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Lectins

Author : Nathan Sharon
ISBN : 9789401148467
Genre : Juvenile Nonfiction
File Size : 78. 20 MB
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A characteristic property of most, or perhaps all, proteins is their ability to combine specifically and reversibly with various substances. Well known examples are enzymes that bind substrates and inhibitors, and antibodies that bind antigens. This book deals with lectins, a class of proteins that bind carbohydrates. Another characteristic property of lectins is that they agglutinate cells or precipitate polysaccharides and glycoproteins. This is because lectins are polyvalent, i.e. each lectin molecule has at least two carbohydrate binding sites to allow crosslinking between cells (by combining with sugars on their surfaces) or between sugar containing macromolecules. The agglutinating and precipitating activities of lectins are very similar to those of antibodies. They can likewise be specifically inhibited by low molecular weight compounds (haptens), which in the case of lectins are sugars or sugar containing compounds (Fig. 1.1). Not surprisingly, therefore, many of the methods used in lectin research are based on immunochemical techniques. Nevertheless, lectins are different from antibodies in several important aspects. Many lectins are found in plants, microorganisms and viruses, which do not synthesize immunoglobulins. In fact, they are found in almost all living organisms (Table 1.1) and are not confined to specific organs or tissues. Another marked difference between the two classes of compound is that antibodies are structurally similar, whereas lectins are structurally diverse. In general, lectins are oligomeric proteins composed of subunits, usually with one sugar binding site per subunit.

Lectins And Glycoconjugates In Oncology

Author : Hans-Joachim Gabius
ISBN : 9783642736629
Genre : Medical
File Size : 83. 14 MB
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Cellular glycoconjugates and their specific receptors, e.g. lectins, form a recognitive and informative transfer system that justifies special scientific and clinical attention. In various contributions reviewing the initiation and recent progress in this rapidly developing field advances in clinical oncology are discussed with regard to basic sciences as well as their application in clinical sciences. The approaches comprise reports from diverse fields such as biochemistry, cell biology, pathology and clinical oncology, addressing questions of how tumors grow and spread, and leading to the improvement of clinical management and tumor diagnosis.

Lectins And Pathology

Author : Michel Caron
ISBN : 9781482283570
Genre : Medical
File Size : 23. 5 MB
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The present understanding of the various implications of lectins in pathology are summarised in this timely text. With contributions from leading investigators in the field of lectin research, Lectins and Pathology provides up-to-date information on key developments within this field, including the use of lectins and lectin-binding molecules as tools, the involvement of endogenous (animal or human) lectins in inflammation, cancer invasion and metastasis, as well as the importance of lectins in bacteriology and parasitology. This volume contains useful knowledge for clinical investigators, cell biologists, biochemists and biotechnologists, as well as for the graduate students interested in getting a comprehensive coverage of this field.

Biology And Treatment Of Colorectal Cancer Metastasis

Author : Anthony J. Mastromarino
ISBN : 9781461323013
Genre : Medical
File Size : 71. 68 MB
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The theme of the current workshop was identified several years ago and was considered by the working group of the National Large Bowel Cancer Project to be an appropriate workshop topic. Although the subject was important then, it was not possible to conduct such a workshop at that time. In the interim, not only did the problems associated with colorectal metastasis still exist, but new insights on the biology and treatment of colorectal cancer metastasis emerged, making the workshop topic especially important and relevant. With input from an expert Planning Committee, a unique program was designed to provide an opportunity for information exchange between basic scientists and clinical investigators. The published proceedings reflect the organization of the workshop which consisted of five sections: Section I. The Biology of Colorectal Cancer Metastasis co-chaired by Drs. J. Isaiah Fidler and George Poste Controversies in the Management of Patients with Colorectal Cancer Section II.

Eat Right 4 Your Type Revised And Updated

Author : Dr. Peter J. D'Adamo
ISBN : 1101042788
Genre : Health & Fitness
File Size : 29. 46 MB
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THE NEW YORK TIMES BESTSELLING DIET PHENOMENON If you’ve ever suspected that not everyone should eat the same thing or do the same exercise, you’re right. In fact, what foods we absorb well and how our bodies handle stress differ with each blood type. Your blood type reflects your internal chemistry. It is the key that unlocks the mysteries of disease, longevity, fitness, and emotional strength. It determines your susceptibility to illness, the foods you should eat, and ways to avoid the most troubling health problems. Based on decades of research and practical application, Eat Right 4 Your Type offers an individualized diet-and-health plan that is right for you. In this revised and updated edition of Eat Right 4 Your Type, you will learn: • Which foods, spices, teas, and condiments will help maintain your optimal health and ideal weight • Which vitamins and supplements to emphasize or avoid • Which medications function best in your system • Whether your stress goes to your muscles or to your nervous system • Whether your stress is relieved better through aerobics or meditation • Whether you should walk, swim, or play tennis or golf as your mode of exercise • How knowing your blood type can help you avoid many common viruses and infections • How knowing your blood type can help you fight back against life-threatening diseases • How to slow down the aging process by avoiding factors that cause rapid cell deterioration INCLUDES A 10-DAY JUMP-START PLAN

Prostate Cancer New Horizons In Research And Treatment

Author : Michael L. Cher
ISBN : 9780306481437
Genre : Medical
File Size : 63. 55 MB
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In recent years the pace of research in prostate cancer has increased dramatically. Creative ideas in combination with new and emerging technologies have led to an explosion of discovery. These types of advances in prostate cancer research presage an era of new treatment strategies based on an understanding of the cellular and molecular mechanisms of disease. In creating this book, we aimed to cover a broad "bench to bedside" research spectrum ranging from: genetic, molecular and cellular analyses to epidemiological studies, refinements in local treatment strategies and new biologically based non-hormonal treatments for systemic disease. Researchers and clinicians will find in this book a group of timely and clinically relevant chapters on prostate cancer research and treatment.

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