investigations in yeast functional genomics and molecular biology

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Investigations In Yeast Functional Genomics And Molecular Biology

Author : Elijah Joshua
ISBN : 1548212458
Genre :
File Size : 71. 69 MB
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This book examines conserved pathways mediating cell cycle progression and cell polarity establishment. It includes examples of yeast, regulatory circuits, and feedback regulation, with emphasis on system-wide approaches. It also covers protein interaction networks and trait locus analysis and presents methods and challenges in comparative genomics analysis and evolutionary genetics.

Investigations In Yeast Functional Genomics And Molecular Biology

Author : Matthew Eckwahl
ISBN : 9781771880107
Genre : Medical
File Size : 64. 57 MB
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This book examines conserved pathways mediating cell cycle progression and cell polarity establishment. It includes examples of yeast, regulatory circuits, and feedback regulation, with emphasis on system-wide approaches. It also covers protein interaction networks and trait locus analysis and presents methods and challenges in comparative genomics analysis and evolutionary genetics.

Guide To Yeast Genetics Functional Genomics Proteomics And Other Systems Analysis

Author :
ISBN : 012375173X
Genre : Science
File Size : 72. 18 MB
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This fully updated edition of the bestselling three-part Methods in Enzymology series, Guide to Yeast Genetics and Molecular Cell Biology is specifically designed to meet the needs of graduate students, postdoctoral students, and researchers by providing all the up-to-date methods necessary to study genes in yeast. Procedures are included that enable newcomers to set up a yeast laboratory and to master basic manipulations. This volume serves as an essential reference for any beginning or experienced researcher in the field. Provides up-to-date methods necessary to study genes in yeast. Includes proceedures that enable newcomers to set up a yeast laboratory and to master basic manipulations. This volume serves as an essential reference for any beginning or experienced researcher in the field.

Metabolome Analyses

Author : Seetharaman Vaidyanathan
ISBN : 9780387252407
Genre : Science
File Size : 66. 66 MB
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Metabolome analysis is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology. This book highlights analytical and bioinformatics strategies now available for investigating metabolic networks in microbial, plant and animal systems. The contributing authors are world leaders in this field and they present an unambiguous case for pursuing metabolome analysis as a means to attain a systems level understanding of complex biological systems.

Microbial Functional Genomics

Author : Jizhong Zhou
ISBN : 0471071900
Genre : Medical
File Size : 89. 42 MB
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Genomics: toward a genome-level understanding of the structure, functions, and evolution of bioloical systems; Microbial diversity and genomics. Computational genome annotation. Microbial evolution from a genomics perspective. Computational methods for functional prediction of genes. DNA microarray technology. Microarray gene expression data analysis. Mutagenesis as a genomic tool for studying gene function. Mass spectrometry. Identification of protein-ligand interactions. The functional genomics of model organisms: addressing old questions from a new perspective. Functional genomic analysis of bacterial pathogens and environmentally significant microorganisms. The impact of genomics on antimicrobial drug discovery and toxicology. Application of microarray-based genomic technology to mutation analysis and microbial detection. Future perspectives: genomics beyond single cells.

Candida

Author : Christophe d' Enfert
ISBN : 9781904455134
Genre : Medical
File Size : 89. 66 MB
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Candida species are important human pathogens that are best known for causing opportunist infections in immunocompromised hosts (e.g. transplant patients, AIDS sufferers, cancer patients). Infections are difficult to treat and can be very serious. 30-40% of systemic infections result in death. The sequencing of the genome of C. albicans and those of several other medically-relevant Candida species has provided a major impetus for Candida comparative and functional genomic analyses. These have provided a fascinating insight into the molecular and cellular biology of these fungi, and these should pave the way for the development of more sensitive diagnostic strategies and novel antifungal therapies. In this timely book, international experts provide comprehensive and authoritative reviews of these important organisms. The topics covered include: genome dynamics of C. albicans; molecular, epidemiological, and population studies of C. albicans; the parasexual cycle in C. albicans; comparative genomics of the hemiascomycetes group and of different Candida species; databases and the challenges that their curators are facing; transcriptome analysis; proteomics; molecular evolution of the genetic code; stress responses; regulation of morphogenesis; cell wall biology; interaction with host cells; analysis of gene function; antifungal resistance mechanisms; and much more. This book is essential reading for all Candida genome and molecular biology researchers and a recommended text for scientists working on fungal genomics and molecular biology.

Plant Functional Genomics

Author : Erich Grotewold
ISBN : 9781592594139
Genre : Science
File Size : 21. 17 MB
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Erich Grotewold has assembled a team of leading plant scientists to describe in detail the most commonly used methods for investigating plant gene function in a wide variety of plants, during plant pathogen interactions, and even in algae. These readily reproducible protocols include computational, molecular, and genetic methodologies designed for both general and specific problems. Here the reader will learn about powerful computational and statistical tools to help predict gene function either on the basis of comparative genomics, or from the analysis of complex genome sequences. Numerous loss-of-function and gain-of-function techniques for discovering gene function are presented in step-by-step detail. Cutting-edge computational, molecular, and genetic protocols for establishing plant gene function Powerful combination of experimental and computer-based methods Loss-of-function and gain-of-function mutant analyses Comprehensive analysis of the bioinformatic tools available to interpret results Comprehensive bibliography.

Molecular Biology Of The Cell

Author : Bruce Alberts
ISBN : 9781317563747
Genre : Science
File Size : 43. 59 MB
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As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.

Molecular Wine Microbiology

Author : Alfonso V. Carrascosa Santiago
ISBN : 0080962580
Genre : Technology & Engineering
File Size : 48. 74 MB
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Molecular Wine Microbiology features rigorous scientific content written at a level comprehensible for wine professionals as well as advanced students. It includes information on production and spoilage issues, the microbial groups relevant for wine production and microbial wine safety. Microbiology has long been recognized as a key tool in studying wine production, however only recently have wine microbiology studies been addressed at a molecular level, increasing the understanding of how microbiology impacts not only the flavor quality of the wine, but also its safety. Understanding, at a molecular level, how a starter culture can impact ethanol, glycerol, volatile phenols, mannoproteins, biogenic amines or ochratoxin A of a wine are just some of the core points that must be considered in order to achieve maximium consumer acceptability while addressing safety concerns during processing and storage. While other books offer insights into the technological aspects of enology, this book is written by expert microbiologists, who explore the positive and negative impacts of gene function in the production of wine, from a microbiological point of view. Winner of the 2012 Jury Award in Enology from the International Organisation of Vine and Wine Presents the most current methods of studying the microbiology of wine Includes latest identification and typing methods, reducing identification time from days and weeks to minutes and hours Provides important knowledge about the impact of microbiological factors at the molecular level for reduction of wine spoilage and increased wine quality and safety

Yeast Gene Analysis

Author :
ISBN : 0080919138
Genre : Science
File Size : 20. 30 MB
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Focusing on Saccharomyces cerevisiae, the second edition of Yeast Gene Analysis represents a major reworking of the original edition, with many completely new chapters and major revisions to all previous chapters. Originally published shortly after completion of the yeast genome sequence, the new edition covers many of the major genome-wide strategies that have been developed since then such as microarray analysis of transcription, synthetic gene array studies, protein microarrays and chemical genetic approaches. It represents a valuable resource for any research laboratory using budding yeast as their experimental system in which to identify new yeast gene functions. The chapters are written in a readable style with useful background information, technical tips and specific experimental protocols included as appropriate, enabling both the novice and the experienced yeast researcher to adopt new procedures with confidence. New chapters on: * strain construction * genome-wide two-hybrid approaches * use of microarrays for transcript analysis * real-time analysis of chromosome behaviour and FRET * synthetic gene array technology and protein arrays * chemical genomics and yeast prions * RNA gene analysis and mitochondrial gene function analysis * phylogenetic footprinting * discovering human gene function and predicting yeast gene function

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