handbook of single molecule biophysics

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Handbook Of Single Molecule Biophysics

Author : Peter Hinterdorfer
ISBN : 0387764976
Genre : Science
File Size : 84. 33 MB
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This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.

Handbook Of Single Molecule Fluorescence Spectroscopy

Author : Chris Gell
ISBN : 9780198529422
Genre : Science
File Size : 57. 59 MB
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This is a practical introduction to single molecule fluorescence experiments, the analysis of the data, and applications of the techniques to the study of biological structure and function.

Single Particle Tracking And Single Molecule Energy Transfer

Author : Christoph Bräuchle
ISBN : 3527628371
Genre : Science
File Size : 30. 88 MB
Format : PDF
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Closing a gap in the literature, this handbook gathers all the information on single particle tracking and single molecule energy transfer. It covers all aspects of this hot and modern topic, from detecting virus entry to membrane diffusion, and from protein folding using spFRET to coupled dye systems, as well recent achievements in the field. Throughout, the first-class editors and top international authors present content of the highest quality, making this a must-have for physical chemists, spectroscopists, molecular physicists and biochemists.

Handbook Of Fluorescence Spectroscopy And Imaging

Author : Markus Sauer
ISBN : 9783527633524
Genre : Science
File Size : 85. 52 MB
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Providing much-needed information on fluorescence spectroscopy and microscopy, this ready reference covers detection techniques, data registration, and the use of spectroscopic tools, as well as new techniques for improving the resolution of optical microscopy below the resolution gap. Starting with the basic principles, the book goes on to treat fluorophores and labeling, single-molecule fluorescence spectroscopy and enzymatics, as well as excited state energy transfer, and super-resolution fluorescence imaging. Examples show how each technique can help in obtaining detailed and refined information from individual molecular systems.

Handbook Of Molecular Biophysics

Author : Henrik G. Bohr
ISBN : 9783527407026
Genre : Science
File Size : 23. 80 MB
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This handbook and reference condenses the biophysics contents of the renowned Encyclopedia of Applied Physics in one handy volume. Twenty-eight carefully written overview articles cover the latest research, including single molecule spectroscopy, biosensors and cellular biomechanics. Readers benefit from concise summaries of the fundamentals, methods and applications, backed by detailed tables of contents for quick access, and glossaries of terms, as well as detailed lists of references and further reading. For libraries and research and development teams in academia and industry. From the contents: Quantum Mechanics Methods for Molecular Biophysics and Electronic Structure Calculations of Biomolecules Studies of Motions of Biomolecules and Molecular Dynamics Calculations Biomolecular Structures and Dynamics in Proteins, Lipids, and DNA Radiation and Spectroscopy Methods in Molecular Biophysics Neurobiophysics and Ion Channels Techniques for Detecting Molecular Structures down to the Single Molecule Level Physical Effects in Biomolecules and larger Organic Systems Molecular Biophysics Applications in Medicine

Handbook Of Molecular Force Spectroscopy

Author : Aleksandr Noy
ISBN : 9780387499895
Genre : Science
File Size : 72. 34 MB
Format : PDF
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Researchers in academia and industry who are interested in techniques for measuring intermolecular forces will find this an essential text. It presents a review of modern force spectroscopy, including fundamentals of intermolecular forces, technical aspects of the force measurements, and practical applications. The handbook begins with a review of the fundamental physics of loading single and multiple chemical bonds on the nanometer scale. It contains a discussion of thermodynamic and kinetic models of binding forces and dissipation effects in nanoscale molecular contacts, covers practical aspects of modern single-molecule level techniques, and concludes with applications of force spectroscopy to chemical and biological processes. Computer modeling of force spectroscopy experiments is also addressed.

Handbook Of Single Molecule Electronics

Author : Kasper Moth-Poulsen
ISBN : 9789814463393
Genre : Science
File Size : 26. 24 MB
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Single-molecule electronics has evolved as a vibrant research field during the last two decades. The vision is to be able to create electronic components at the highest level of miniaturization—the single molecule. This book compiles and details cutting-edge research with contributions from chemists, physicists, theoreticians, and engineers. It covers all aspects of single-molecule electronics, from the theory through experimental realizations and the chemical synthesis of molecular components to the implementation of molecular components in future integrated circuits. This book describes in detail both established methods and recent advances in the field, including vibrational effects, switching phenomena, quantum interference, thermal power, and parallel assembly strategies. The authors add more details to the chapters than typically found in the primary literature so that the book can be read not only by specialists but also by non-experts and students with an interest in the research field. Each chapter is accompanied by problems, and a solutions manual is also provided.

Biomembrane Frontiers

Author : Thomas Jue
ISBN : 9781607613145
Genre : Science
File Size : 66. 2 MB
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This is the second book in the Handbook of Modern Biophysics series, dedicated to fundamental topics and new applications in biophysics. This book on biomembranes covers theory and application and includes problem sets, references and guides for further study.

Handbook Of Dynein

Author : Keiko Hirose
ISBN : 9789814303330
Genre : Science
File Size : 71. 81 MB
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This book draws together recent data on both cytoplasmic and flagellar dyneins and the proteins they interact with, to give readers a clear picture of what is currently known about the structure and mechanics of these remarkable macro-molecular machines. Each chapter is written by active researchers, with a focus on currently used biophysical, biochemical, and cell biological methods. This is a useful handbook for frontline researchers as well as a textbook for advanced students. Besides comprehensive cover of structural information gained by electron microscopy, electron cryo-tomography, X-ray crystallography, and nuclear magnetic resonance, this book provides detailed descriptions of mechanistic experiments by single-molecule nanometry. The reports include in vitro studies of the motility of reconstituted complexes and in vivo studies of organisms expressing mutant dyneins. The recent technical improvements described, which have played an important part in recent advances, include the expression and preparation of recombinant dynein heavy chains or individual subdomains.

Handbook Of Pharmaceutical Wet Granulation

Author : Ajit S. Narang
ISBN : 9780323481038
Genre : Medical
File Size : 50. 71 MB
Format : PDF, Docs
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Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. The books' focus on process analytical technology, quality by design principles, granulation equipment, modeling, scale-up, control and real time release makes it a timely and valuable resource for all those involved in pharmaceutical wet granulation. Discusses fundamentals of theory and current industrial practice in the field of wet granulation, including product and process design and role of material properties in wet granulation Examines the modern evolution of wet granulation through current topics such as established and novel process analytical technologies (PATs), and product development and scale-up paradigms Written for scientists working within the pharmaceutical industry, as well as academics, regulatory officials and equipment vendors who provide PAT tools and granulation equipment

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