genetic mapping in experimental populations

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Genetic Mapping In Experimental Populations

Author : J. W. Van Ooijen
ISBN : 9781107013216
Genre : Mathematics
File Size : 87. 35 MB
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Genetic linkage maps are an increasingly important tool in both fundamental and applied research, enabling the study and deployment of genes that determine important biological traits. This concise introduction to genetic mapping in species with disomic inheritance enables life science graduate students and researchers to use mapping software to produce more reliable results. After a brief refresher on meiosis and genetic recombination, the steps in the map construction procedure are described, with explanations of the computations involved. The emphasis throughout is on the practical application of the methods described; detailed mathematical formulae are avoided and exercises are included to help readers consolidate their understanding. A chapter on recognising and solving problems provides valuable guidance for dealing with real-life situations. An extensive chapter dedicated to the more complex situation of outbreeding species offers a unique insight into the approach required for many economically important and model species, both plants and animals.

Genetic Mapping And Marker Assisted Selection

Author : N Manikanda Boopathi
ISBN : 9788132209584
Genre : Science
File Size : 34. 42 MB
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Genetic mapping and marker assisted selection (MAS) is considered as one of the major tools in genetic improvement of crop plants in this genomics era. This book describes basics in linkage mapping, step-by-step procedure to perform MAS, achievements made so far in different crops, and limitations and prospects of MAS in plant breeding. It summarizes all this in a simple but comprehensive mode using suitable examples so as to explain the concept and its historical developments. To summarize, this book describes technologies for identification of genes of interest through genetic mapping, recaps the major applications of MAS to plant breeding; lists examples in which MAS is being applied to various breeding programs, and emphasizes the various difficulties that limit the application of MAS in plant breeding, providing possible solutions to overcome these difficulties, and finally tries to illustrate the future prospects. This book would be a valuable guide to the under-graduates and post-graduates of agricultural universities and institutes that are interested and/or involved in genetic improvement of crop plants using modern tools. Bibliography listed in this book constitutes two parts: literature cited and further reading. Literature cited contains references cited in the text and further information on the given concept/technique can be obtained from these references. Further reading provides a list of suggested readings for in-depth coverage of the topics.

Bioinformatics In Aquaculture

Author : Zhanjiang (John) Liu
ISBN : 9781118782385
Genre : Computers
File Size : 57. 59 MB
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Bioinformatics derives knowledge from computer analysis of biological data. In particular, genomic and transcriptomic datasets are processed, analysed and, whenever possible, associated with experimental results from various sources, to draw structural, organizational, and functional information relevant to biology. Research in bioinformatics includes method development for storage, retrieval, and analysis of the data. Bioinformatics in Aquaculture provides the most up to date reviews of next generation sequencing technologies, their applications in aquaculture, and principles and methodologies for the analysis of genomic and transcriptomic large datasets using bioinformatic methods, algorithm, and databases. The book is unique in providing guidance for the best software packages suitable for various analysis, providing detailed examples of using bioinformatic software and command lines in the context of real world experiments. This book is a vital tool for all those working in genomics, molecular biology, biochemistry and genetics related to aquaculture, and computational and biological sciences.

11th International Wheat Genetics Symposium 2008 Proceedings

Author : Rudi Appels
ISBN : 9781920899103
Genre : Wheat
File Size : 90. 95 MB
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The Statistics Of Gene Mapping

Author : David Siegmund
ISBN : 9780387496863
Genre : Medical
File Size : 84. 19 MB
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This book details the statistical concepts used in gene mapping, first in the experimental context of crosses of inbred lines and then in outbred populations, primarily humans. It presents elementary principles of probability and statistics, which are implemented by computational tools based on the R programming language to simulate genetic experiments and evaluate statistical analyses. Each chapter contains exercises, both theoretical and computational, some routine and others that are more challenging. The R programming language is developed in the text.

Bayesian Inference For Gene Expression And Proteomics

Author : Kim-Anh Do
ISBN : 9780521860925
Genre : Mathematics
File Size : 75. 79 MB
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Expert overviews of Bayesian methodology, tools and software for multi-platform high-throughput experimentation.

Molecular Approaches To Ecology And Evolution

Author : R. deSalle
ISBN : 3764357258
Genre : Medical
File Size : 30. 67 MB
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The last ten years have seen an explosion of activity in the application of molecular biological techniques to evolutionary and ecological studies. This volume attempts to summarize advances in the field and place into context the wide variety of methods available to ecologists and evolutionary biologists using molecular techniques. Both the molecular techniques and the variety of methods available for the analysis of such data are presented in the text. The book has three major sections - populations, species and higher taxa. Each of these sections contains chapters by leading scientists working at these levels, where clear and concise discussion of technology and implication of results are presented. The volume is intended for advanced students of ecology and evolution and would be a suitable textbook for advanced undergraduate and graduate student seminar courses.

Phenotypes And Genotypes

Author : Florian Frommlet
ISBN : 9781447153108
Genre : Computers
File Size : 75. 74 MB
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This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.

Genetic Improvement Of Rice For Water Limited Environments

Author : Osamu Ito
ISBN : 9789712201387
Genre : Plant-water relationships
File Size : 68. 46 MB
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Applications Of Gene Based Technologies For Improving Animal Production And Health In Developing Countries

Author : Harinder P.S. Makkar
ISBN : 9781402033117
Genre : Science
File Size : 66. 7 MB
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Modern Biotechnology has potential for solving many problems associated with animal productivity and health and offers exciting opportunities for enhancing agricultural productivity. At present the focus is, however, on the issues and problems of significance for livestock producers in the developed world. In order to fully realize the benefits of this technology in developing countries, there is a need to identify, characterize and apply appropriate gene-based technologies for these regions. These proceedings present peer reviewed state-of-the-art papers describing the achievements in the areas of animal breeding and genetics, animal nutrition, animal health, and environment, ethics, safety, and regulatory aspects of gene-based technologies; achievements which could be realized using these modern scientific tools to maximise the benefits from the 'livestock revolution' that is taking place; and the constraints in the use of gene-based technologies and their specific research needs. This book will help in bridging the wide gap between developed and developing countries, in the development and use of gene-based technologies, and to elucidate the current and future roles of such technologies in the developing world. It is a good reference source for researchers, students and policy-makers alike.

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