fundamentals of maldi tof ms analysis applications in bio diagnosis tissue engineering and drug delivery springerbriefs in applied sciences and technology

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Fundamentals Of Maldi Tof Ms Analysis

Author : Samira Hosseini
ISBN : 9789811023569
Genre : Technology & Engineering
File Size : 45. 58 MB
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This book presents the fundamentals and applications of Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-ToF-MS) technique. It highlights the basic principles, the history of invention as well as the mechanism of ionization and mass determination using this technique. It describes the fundamental principles and methods for MALDI spectra interpretation and determination of exact chemical structures from experimental data. This book guides the reader through the interpretation of MALDI data where complex macromolecular spectra are simplified in order to present the major principles behind data interpretation. In addition, each chapter describes how MALDI-ToF-MS analysis provides necessary understanding of the copolymer systems that have been designed for specialized biomedical applications.

Novel Polymeric Biochips For Enhanced Detection Of Infectious Diseases

Author : Samira Hosseini
ISBN : 9789811001079
Genre : Technology & Engineering
File Size : 38. 14 MB
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This book focuses on the creation and development of polymeric platforms (different compositions) from a specific polymer system. This system can be used as an adaptive technique for producing sensitive analytical devices, or for simple integration into existing bioanalytical tools in order to enhance the detection signal.

Biocompatible Graphene For Bioanalytical Applications

Author : Yuwei Hu
ISBN : 9783662456958
Genre : Science
File Size : 45. 49 MB
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This book highlights the latest advances in the use of graphene and bio-compatible-material-decorated graphene to detect various targets (e.g. DNA, RNA, amino acids, peptides, proteins, enzymes, antigens, glucose, DA, AA, UA, ATP, NADH, gas, ions, etc.). It focuses on the specific interaction of these substances with graphene (or modified graphene) and the efficient transduction of the target recognition event into detectable signals via various techniques. Particular emphasis is given to well-designed strategies for constructing graphene-based platforms and target determination. It also covers other bio-analytical applications including cellular imaging, drug delivery and bacteria inhibition, before turning to a discussion of future challenges and prospects of graphene in bio-analytical applications. This book is intended for researchers working in the fields of analytical chemistry, nanomaterials and biomedical engineering. Li Niu is a Professor at the State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences.

Additive Manufacturing Technologies

Author : Ian Gibson
ISBN : 9781493921133
Genre : Technology & Engineering
File Size : 50. 45 MB
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This book covers in detail the various aspects of joining materials to form parts. A conceptual overview of rapid prototyping and layered manufacturing is given, beginning with the fundamentals so that readers can get up to speed quickly. Unusual and emerging applications such as micro-scale manufacturing, medical applications, aerospace, and rapid manufacturing are also discussed. This book provides a comprehensive overview of rapid prototyping technologies as well as support technologies such as software systems, vacuum casting, investment casting, plating, infiltration and other systems. This book also: Reflects recent developments and trends and adheres to the ASTM, SI, and other standards Includes chapters on automotive technology, aerospace technology and low-cost AM technologies Provides a broad range of technical questions to ensure comprehensive understanding of the concepts covered

Magnesium Biomaterials

Author : Nicholas Travis Kirkland
ISBN : 9783319021232
Genre : Technology & Engineering
File Size : 79. 47 MB
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Magnesium Biomaterials provides a succinct up-to-date overview of Magnesium biomaterial development, critically examines the types of in vitro experiments that may be performed, and investigates the numerous variables that affect Magnesium biodegradation when undertaking these experiments. This work also discusses the direction in which current Magnesium biomaterial development is heading and the necessary steps for future development of this field. Information is drawn from numerous multi-disciplinary sources to provide a coherent and critical overview. Magnesium Biomaterials is ideal for researchers in the area of bio-Mg, companies interested in exploring their own alloys, and for researchers working with other biodegradable materials who are seeking a cross-platform understanding of material performance.

Spions As Nano Theranostics Agents

Author : Atefeh Zarepour
ISBN : 9789811035630
Genre : Technology & Engineering
File Size : 25. 50 MB
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This Brief introduces SuperParamagnetic Iron Oxide Nanoparticles (SPIONs), the different synthesis approaches, their applications in the field of diagnostics and treatment and finally as theranostic agents in cancer.

Heavy Metal Stress In Plants

Author : Dharmendra K. Gupta
ISBN : 9783642384691
Genre : Science
File Size : 70. 5 MB
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Plants possess a range of potential cellular mechanisms that may be involved in the detoxification of heavy metals and thus tolerance to metal stress. Metal toxicity causes multiple direct and indirect effects in plants that concern practically all physiological functions. The main purpose of this book is to present comprehensive and concise information on recent advances in the field of metal transport and how genetic diversity affects heavy metal transport in plants. Other key futures of the book are related to metal toxicity and detoxification mechanisms, biochemical tools for HM remediation processes, molecular mechanisms for HM detoxification, how metallomics and metalloproteomics are affected by heavy metal stress in plants, and the role of ROS metabolism in the alleviation of heavy metals. Some chapters also focus on recent developments in the field of phytoremediation. Overall the book presents in-depth information and the most essential advances in the field of heavy metal toxicity in plants in recent years.

Fundamentals Of Power Electronics

Author : Erickson
ISBN : 9781461576464
Genre : Technology & Engineering
File Size : 70. 30 MB
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In many university curricula, the power electronics field has evolved beyond the status of comprising one or two special-topics courses. Often there are several courses dealing with the power electronics field, covering the topics of converters, motor drives, and power devices, with possibly additional advanced courses in these areas as well. There may also be more traditional power-area courses in energy conversion, machines, and power systems. In the breadth vs. depth tradeoff, it no longer makes sense for one textbook to attempt to cover all of these courses; indeed, each course should ideally employ a dedicated textbook. This text is intended for use in introductory power electronics courses on converters, taught at the senior or first-year graduate level. There is sufficient material for a one year course or, at a faster pace with some material omitted, for two quarters or one semester. The first class on converters has been called a way of enticing control and electronics students into the power area via the "back door". The power electronics field is quite broad, and includes fundamentals in the areas of • Converter circuits and electronics • Control systems • Magnetics • Power applications • Design-oriented analysis This wide variety of areas is one of the things which makes the field so interesting and appealing to newcomers. This breadth also makes teaching the field a challenging undertaking, because one cannot assume that all students enrolled in the class have solid prerequisite knowledge in so many areas.

Advanced Techniques In Diagnostic Microbiology

Author : Yi-Wei Tang
ISBN : 9781461439707
Genre : Medical
File Size : 61. 65 MB
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In the United States, hospitals annually report over 5 million cases of infectious-disease-related illnesses: clinical microbiology laboratories in these hospitals are engaged in detecting and identifying the pathogenic microorganisms in clinical specimens collected from these patients with suspected infections. Clearly, the timely and accurate detection/identification of these microbial pathogens is critical for patient treatment decisions and outcomes for millions of patients each year. Despite an appreciation that the outcome of an infectious-disease-related illness is directly related to the time required to detect and identify a microbial pathogen, clinical microbiology laboratories in the United States as well as worldwide have long been hampered by traditional culture-based assays, which may require prolonged incubation time for slowly growing microorganisms such as Mycobacterium tuberculosis. Moreover, traditional culture-based assays often require multiple steps with additional time needed for discernment of species and/or detection of antimicrobial resistance. Finally, these traditional, slow multistep culture-based assays are labor-intensive and required skilled clinical microbiologists at the bench. Over the past several decades, advanced molecular techniques in diagnostic microbiology quietly have been revolutionizing the practice of clinical microbiology in the hospital setting. Indeed, molecular diagnostic testing in general and nucleic-acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. There is no question that the development of rapid molecular techniques for nucleic acid amplification/characterization combined with automation and user-friendly software has greatly broadened the diagnostic capabilities of the clinical microbiology laboratory. These technical advances in molecular microbiology over the first decade of the 21st Century have profoundly influenced the physical structure of clinical microbiology laboratories as well as their staffing patterns, workflow, and turnaround time. These molecular microbiology advances have also resulted in the need for a revised and updated second edition of Advanced Techniques in Diagnostic Microbiology. This second edition again provides an updated and comprehensive description of the ongoing evolution of molecular methods for the diagnosis of infectious diseases. In addition, many new chapters have been added, including a chapter on the clinical interpretation and relevance of advanced technique results. The second edition, like the first edition, includes both a “techniques” section describing the latest molecular techniques and an “applications” section describing how these advanced molecular techniques are being used in the clinical setting. Finally, the second edition, like the first edition, utilizes a diverse team of authors who have compiled chapters that provide the reader with comprehensive and useable information on advanced molecular microbiology techniques.

Data Engineering And Intelligent Computing

Author : Suresh Chandra Satapathy
ISBN : 9789811032233
Genre : Computers
File Size : 56. 43 MB
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The book is a compilation of high-quality scientific papers presented at the 3rd International Conference on Computer & Communication Technologies (IC3T 2016). The individual papers address cutting-edge technologies and applications of soft computing, artificial intelligence and communication. In addition, a variety of further topics are discussed, which include data mining, machine intelligence, fuzzy computing, sensor networks, signal and image processing, human-computer interaction, web intelligence, etc. As such, it offers readers a valuable and unique resource.

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