forensic dna analysis current practices and emerging technologies

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Forensic Dna Analysis

Author : Jaiprakash G. Shewale
ISBN : 9781466571365
Genre : Law
File Size : 33. 32 MB
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The field of forensic DNA analysis has grown immensely in the past two decades and genotyping of biological samples is now routinely performed in human identification (HID) laboratories. Application areas include paternity testing, forensic casework, family lineage studies, identification of human remains, and DNA databasing. Forensic DNA Analysis: Current Practices and Emerging Technologies explores the fundamental principles and the application of technologies for each aspect of forensic DNA analysis. The book begins by discussing the value of DNA evidence and how to properly recognize, document, collect, and store it. The remaining chapters examine: The most widely adopted methods and the best practices for DNA isolation from forensic biological samples and human remains Studies carried out on the use of both messenger RNA and small (micro) RNA profiling Real-time polymerase chain reaction (PCR) methods for quantification and assessment of human DNA prior to genotyping Capillary electrophoresis (CE) as a tool for forensic DNA analysis Next-generation short tandem repeat (STR) genotyping kits for forensic applications, the biological nature of STR loci, and Y-chromosome STRs (Y-STRs) Mitochondrial DNA (mtDNA) sequence analysis Single nucleotide polymorphisms (SNPs) and insertion/deletion polymorphisms (indels) in typing highly degraded DNA Deep-sequencing technologies The current state of integrated systems in forensic DNA analysis The book concludes by discussing various aspects of sample-processing training and the entities that provide such training programs. This volume is an essential resource for students, researchers, teaching faculties, and other professionals interested in human identification/forensic DNA analysis.

Dna Fingerprinting Advancements And Future Endeavors

Author : Hirak Ranjan Dash
ISBN : 9789811315831
Genre : Medical
File Size : 20. 61 MB
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This book describes the basics and various applications of DNA fingerprinting, including in actual case studies. The book is divided in four modules; Module 1: Basics of DNA Fingerprinting, Module 2: Applications of DNA Fingerprinting, Module 3: DNA Fingerprinting: Case Studies, and Module 4: Future of DNA Fingerprinting. Each module consists of 4 to 5 chapters, written by reputed researchers, academics and forensic scientists from around the globe. The respective chapters cover e.g. related fields, the tools and techniques used, various genotyping kits, real-world case studies, ancient DNA and wild life forensics, molecular diagnosis of human diseases, legal aspects, microbial forensics and the economics of the DNA fingerprinting technique. The book offers a practical guide for professionals, graduate and post-graduate students in the fields of Forensic Science, Medicine, Genetics, Anthropology, Microbiology, and Zoology. It also serves as a useful reference resource, summarizing major technological advances in the field of DNA fingerprinting, the problems faced in this field of science and possible new solutions to these problems. Presently, DNA fingerprinting is utilized in solving the majority of criminal cases; as such, the book is also helpful for investigating agencies, as it includes representative case studies.

Soudn L Ka Stv I D L

Author : Hirt Miroslav
ISBN : 9788024799520
Genre : Medical
File Size : 30. 91 MB
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Základní učebnice váoboru, na které se podíleli odborníci ze všech soudnělékařských zařízení váČeské republice a částečně i Slovenské republice. Text je strukturován tak, že může sloužit jako učebnice pregraduální, ale i jako jediná současná domácí učebnice postgraduální. Informace jsou určeny nejen soudním lékařům, ale i dalším medicínským a právním oborům.

An Introduction To Forensic Dna Analysis Second Edition

Author : Norah Rudin
ISBN : 1420058509
Genre : Law
File Size : 88. 44 MB
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Significant advances in DNA analysis techniques have surfaced since the 1997 publication of the bestselling An Introduction to Forensic DNA Analysis. DNA typing has become increasingly automated and miniaturized. Also, with the advent of Short Tandem Repeat (STR) technology, even the most minute sample of degraded DNA can yield a profile, providing valuable case information. However, just as the judicial system slowly and reluctantly accepted RFLP and AmpliType® PM+DQA1 typing, it is now scrutinizing the admissibility of STRs. Acknowledging STR typing as the current system of choice, An Introduction to Forensic DNA Analysis, Second Edition translates new and established concepts into plain English so that laypeople can gain insight into how DNA analysis works, from sample collection to interpretation of results. In response to the shift toward more efficient techniques, the authors cover the legal admissibility of STR typing, expand the chapter on DNA databases, and revise the section on automated analysis. They also present key decisions and appellate or supreme court rulings that provide precedent at the state and federal levels. Discussing forensic DNA issues from both a scientific and a legal perspective, the authors of An Introduction to Forensic DNA Analysis, Second Edition present the material in a manner understandable by professionals in the legal system, law enforcement, and forensic science. They cover general principles in a clear fashion and include a glossary of terms and other useful appendices for easy reference.

Current Practice In Forensic Medicine

Author : John A. M. Gall
ISBN : 9781119956501
Genre : Medical
File Size : 52. 88 MB
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Although forensic medicine has been in existence for centuries in one guise or another, it is only with the recent growth in international research that it has begun to be acknowledged as a specific discipline in its own right. Many areas of progress are being made and this text aims to provide a unique, in-depth and critical update on selected topics that are of direct relevance to those practicing in the field including lawyers, police, medical and dental practitioners, forensic scientists and postgraduate/undergraduate medical students and undergraduate law students preparing for forensic medicine examinations. This volume is designed to cover the wider aspects of forensic medicine, including the law, science, medicine (forensic pathology, clinical forensic medicine and forensic psychiatry) and dentistry. Topics covered include subjects of debate and/or uncertainty in areas where significant advances have been made and in those of current relevance to the forensic profession, Chapters provide a variety of approaches to the areas under discussion with reviews of current knowledge, information on significant changes and pointers to the future that the reader should be aware of. Features: An authoritative review, for forensic medicine practitioners throughout the world, from leading international experts in the field. Provides critical commentary and updates on current practice. Topics include: a guide to the presentation of forensic medical evidence, bioterrorism, the paediatric hymen, assessment and interpretation of bone trauma in children, adult sexual assault, genital photography, forensic photography, common errors in injury interpretation, self-inflicted injuries and associated psychological profiles, bite marks and the role of the pathologist in aviation disasters. Includes a wealth of four colour figures to illustrate key points discussed within the text.

Forensic Dna Applications

Author : Dragan Primorac
ISBN : 9781466580237
Genre : Law
File Size : 87. 21 MB
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Forensic DNA Applications: An Interdisciplinary Perspective was developed as an outgrowth of a conference held by the International Society of Applied Biological Sciences. The topic was human genome–based applications in forensic science, anthropology, and individualized medicine. Assembling the contributions of contributors from numerous regions around the world, this volume is designed as both a textbook for forensic molecular biology students and a reference for practitioners and those in the legal system. The book begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples, mitochondrial DNA testing, Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs), and X SNP and STR testing. It also explores low copy number DNA typing, mixtures, and quality assurance and control. The second section examines the collection and preservation of biological evidence under a variety of different circumstances and the identification of human remains—including in mass disaster settings. It discusses applications to bioterrorism investigations, animal DNA testing in criminal cases, pedigree questions and wildlife forensic problems, applications in forensic entomology, and forensic botany. The third section explores recent developments and new technologies, including the rigorous identification of tissue of origin, mtDNA profiling using immobilized probe strips, chips and next-generation sequencing, the use of SNPs to ascertain phenotypic characteristics, and the "molecular autopsy" that looks at aspects of toxicogenetics and pharmacogenetics. The book concludes with a discussion on law, ethics, and policy. It examines the use of DNA evidence in the criminal justice system in both the United States and Europe, ethical issues in forensic laboratory practices, familial searches, DNA databases, ancestry searches, physical phenotyping, and report writing. The contributors also examine DNA applications in immigration and human trafficking cases and international perspectives on DNA databases.

Genetic Suspects

Author : Richard Hindmarsh
ISBN : 9781139490825
Genre : Medical
File Size : 32. 49 MB
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As DNA forensic profiling and databasing become established as key technologies in the toolbox of the forensic sciences, their expanding use raises important issues that promise to touch everyone's lives. In an authoritative global investigation of a diverse range of countries, including those at the forefront of these technologies' development and use, this book identifies and provides critical reflection upon the many issues of privacy; distributive justice; DNA information system ownership; biosurveillance; function creep; the reliability of collection, storage and analysis of DNA profiles; the possibility of transferring medical DNA information to forensics databases; and democratic involvement and transparency in governance, an emergent key theme. This book is timely and significant in providing the essential background and discussion of the ethical, legal and societal dimensions for academics, practitioners, public interest and criminal justice organisations, and students of the life sciences, law, politics, and sociology.

Establishing Precompetitive Collaborations To Stimulate Genomics Driven Product Development

Author : Institute of Medicine
ISBN : 9780309209618
Genre : Medical
File Size : 67. 82 MB
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Despite the many basic research discoveries in genetics, relatively few gene-based treatments, drugs, or preventative measures have been developed. One way to bridge this gap may be for industry, academia, and government to develop partnerships that share resources while distributing risk. However, intellectual property protections and other barriers can inhibit collaborative efforts. The Institute of Medicine held a workshop on July 22, 2010, to explore these issues and develop solutions.

Dna Technology And Forensic Science

Author : Jack Ballantyne
ISBN : UOM:39015015477733
Genre : Medical
File Size : 54. 60 MB
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Molecular biologists, legal authorities, forensic scientists, and policy analysts address questions of policy such as: Should DNA taken for identification be used to determine other genetic characteristics? Should there be different standards of admissibility for DNA evidence compared with other typ

Department Of Justice Fiscal Year 2000 Budget Oversight

Author : United States. Congress. Senate. Committee on the Judiciary
ISBN : 0160601827
Genre : Criminal justice, Administration of
File Size : 77. 45 MB
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