experimental and surgical techniques in the rat

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Experimental And Surgical Technique In The Rat

Author : H. Bryan Waynforth
ISBN : 0127388516
Genre : Medical
File Size : 44. 47 MB
Format : PDF
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The publication of this Second Edition, twelve years after the first, attests to the timelessness of the techniques used in experimental work with the rat. However, scientific progress inevitably brings to light new ideas and procedures. In particular, considerable progress has been made in the use of new anesthetics and analgesics. A completely new chapter has been written on these with unique emphasis on the applicability to the rat. The very variable standards of surgery that existed in the past are placed in perspective in another new chapter, which makes recommendations more in keeping with the higher standards now demanded of animal experimentation. A variety of new techniques have been added throughout to expand the usefulness of the book, and more illustrations have been added to help in the execution of the various procedures. One of the greatest advances in the last twelve years is a greater appreciation for the well-being of experimental animals, and references to a more humane and refined approach have been made throughout this edition. This greater awareness of welfare issues demands that experimental animals be handled and used correctly and compassionately, with as little suffering as possible, and has led to a marked improvement in the attitude to proper training. This book is still the only source which provides a detailed and up-to-date compilation of illustrated experimental methods for work with the rat. It will continue to be an invaluable reference to specific information for laboratory workers and will help considerably in training new investigators in the proper and considerate use of this species. Key Features * All surgical techniques have been revised and updated * A new section on anesthesia and post-operative care has been included * Presents new techniques, particularly cannulation

Experimental Surgical Models In The Laboratory Rat

Author : Alfredo Rigalli
ISBN : 1420093274
Genre : Medical
File Size : 60. 29 MB
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An All-Inclusive Guide to Surgical Techniques on Rats The design of an adequate surgical model, like the choice of the animal model itself, is extremely important for obtaining reliable valuable data. Experimental Surgical Models in the Laboratory Rat summarizes a series of techniques that were applied in the Bone Biology Laboratories, School of Medicine, Rosario National University, Argentina. Stopping just short of an exhaustive analysis of the techniques, this manual describes the basics of each surgical technique, the necessary materials, precautions to consider, the methodology to apply, and the possible results to be obtained in similar experiments. CD-ROM: 250 Illustrations of Surgery Techniques with Step-by-Step Instruction With succinct descriptions, color photographs, and easy-to-follow steps, the attached CD-ROM is a practical, full-color roadmap for performing various surgery techniques, such as catheterization, tracheostomy, intramuscular injection, subcutaneous injection, intraperitoneal injection, and oral intubation. This definitive work provides technical and practical data including volumes and concentrations of solutions, catheters used, equipment, and biological variables on the rat. Experimental Surgical Models in the Laboratory Rat is a complete reference for today’s biomedical sciences investigator.

Rat Experimental Transplantation Surgery

Author : Peter Girman
ISBN : 9783319145594
Genre : Medical
File Size : 48. 14 MB
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The aim of the book is to describe tested microsurgical procedures of kidney, pancreas, islets, heat, liver and small bowel transplantation. All procedures written in the book are used in our experimental research laboratory and their description will be provided by an experienced researcher. The book is organized into ‘General’ and ‘Specific’ sections. The ‘General’ section will include principles, doses and available drugs for rat anaesthesia, the surgical anatomy of the rat, a brief review of immunosuppressant’s used in rat models, a description of basic surgical techniques and blood sampling. The ‘Specific’ section will include a description of the rat model with the appropriate organ failure relevant to the organ transplantation, which will be followed by a detailed description of the surgical procedure with high quality pictures of key steps. Each chapter will describe ‘tips and tricks’ including practical advice and recommendations.

Handbook Of Laboratory Animal Science

Author : Jann Hau
ISBN : 9781420040913
Genre : Medical
File Size : 74. 41 MB
Format : PDF
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The second edition of an international bestseller, this book provides veterinary specialists as well as veterinary and biomedical researchers with detailed information about laboratory animal genetics, diseases, health monitoring, nutrition, and environmental impact on animal experiments. Completely revised and updated, Volume I now contains expanded coverage of topics such as procedures in genetic engineering, surgical techniques, and humane endpoints and the treatment of pain and suffering in laboratory animals. It includes a new, streamlined chapter that combines the review of alternative techniques to animal experimentation such as the use of isolated organs, cell cultures, and computer simulations.

The Iacuc Handbook Second Edition

Author : Jerald Silverman
ISBN : 0849340101
Genre : Medical
File Size : 72. 77 MB
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Since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States. By addressing questions and problems that often confront institutions, The IACUC Handbook, Second Edition provides accurate, succinct answers. It features comprehensive updates for all pertinent federal laws, regulations, and policies. It also contains an expanded survey of IACUC practices from institutions around the nation. With accessible information, this new editionprovides a foundation for those attempting to understand and implement the many and varied responsibilities of these committees.

Essentials Of Experimental Surgery

Author : H Gregerson
ISBN : 3718654962
Genre : Medical
File Size : 51. 18 MB
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This book covers all aspects of experimental gastrointestinal research including anatomy, physiology, surgical procedures and animal experimental models As well as being a useful reference guide to established scientists, it serves as an ideal introduction to the field of gastroenterology By consulting the book, the appropriate animal species and experimental model can be chosen for physiological and pathophysiological studies

Essentials Of Experimental Surgery

Author : John Stuart Penton Lumley
ISBN : 0407013954
Genre : Medical
File Size : 63. 25 MB
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Mosby S Comprehensive Review For Veterinary Technicians E Book

Author : Monica M. Tighe
ISBN : 9780323075688
Genre : Medical
File Size : 25. 31 MB
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Mosby's Comprehensive Review for Veterinary Technicians, 3rd edition introduces and reviews the material in each of your veterinary technology courses. Key topics ranging from basic and clinical science, diagnostics and applications, to professional practices and issues are presented in a user-friendly outline format that is ideal whether you're a new student or you're reviewing for your certification exams. This title includes additional digital media when purchased in print format. For this digital book edition, media content is not included. Comprehensive coverage of veterinary technology spans basic and clinical sciences, applications, patient management, nursing, nutrition, anesthesia and pharmacology, as well as personal, practice and professional management skills - everything you need for both the U.S. and Canadian certification exams. Care of large animals, birds, reptiles and laboratory animals, in addition to cats and dogs, is included. Chapter outlines, learning outcomes and expanded glossaries help you comprehend and retain essential material. Summary tables are ideal for reference or review. Review questions at the end of each chapter, in addition to a 300-question comprehensive review exam, test and reinforce your knowledge of veterinary technology. Six appendixes ensure crucial resources are always at your fingertips. State-of-the-art Alternative Imaging Technology chapter discusses computed tomography and nuclear scintigraphy to complement ultrasound technology. Enhanced content highlights vet tech responsibilities in genetics, small animal nursing, veterinary dentistry, zoonoses, breeding/reproduction, neonatal care, and much more. Small animal nursing instruction now includes dermatology, auricular treatments and ophthalmology. Extended pharmacology coverage features pain management. Personal and practice management skills include expanded OSHA/WHMIS guidelines and ethics discussions.

Handbook Of Laboratory Animal Science Volume I Third Edition

Author : Jann Hau
ISBN : 1420084569
Genre : Medical
File Size : 39. 55 MB
Format : PDF
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Laboratory animal testing provides most of our current knowledge of human physiology, microbiology, immunology, pharmacology, and pathology. From studies of genetics in fruit flies to studies of cellular processes in genetically modified mice to recent dramatic developments in genetics, translational research, and personalized medicines, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences and all rely on access to high-quality laboratory animals as models for humans. Rooted in the principle that good science can only be performed in environments that promote good animal welfare, this third edition of the bestselling Handbook of Laboratory Animal Science, Vol. 1, Essential Principles and Practices emphasizes the importance of implementing the three R’s: replacing live animals with alternative methods, reducing the number of animals used, and refining techniques to minimize animal discomfort, and integrates these humane principles into almost every chapter. See what's new in the Third Edition: New chapters: Applications of Radio-Telemetry in Small Laboratory Animals, Generation and analysis of genetically modified mice, and Physiological, Hematological, and Clinical Chemistry Parameters Additional mateiral on the international harmonization of practices and on the continued implementation of the refinement, reduction, and replacement of animal usage in laboratories Sixteen page color insert Relevant to virtually all areas of laboratory science and forming the cornerstone of laboratory animal science, each individual chapter focuses on an important subdiscipline of laboratory animal science including humane laws and guidelines; non-surgical, surgical, microsurgical, and post-mortem procedures; genetic modification; nutrition, feeding, and environmental factors; experiment design and alternative methods; and analgesia, anesthesia, and euthanasia. Each chapter can be read in series or as a stand alone text. A truly international effort from world renowned contributors, Handbook of Laboratory Animal Science, Vol. 1, Essential Principles and Practices, Third Edition is useful as a textbook in laboratory animal science courses for postgraduate and undergraduate students, as a handbook for scientists who work with animals in their research, and for university veterinarians, regulators, and other specialists in laboratory animal science.

The Cellular Basis Of Cardiovascular Function In Health And Disease

Author : Pawan K. Singal
ISBN : 0792399749
Genre : Science
File Size : 24. 97 MB
Format : PDF, Kindle
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This special issue of Molecular and Cellular Biochemistry contains original research articles and review papers which were invited from the participants of a recent meeting organized to honour the 60th birthday of Naranjan S. Dhalla, Ph.D., M.D.(Hon.). The meeting, organized by Drs. Morris Karmazyn (London), Grant Pierce (Winnipeg) and Balwant Tuana (Ottawa), was held at the Best Western Lakeside Inn in Kenora, Ontario, Canada on August 23-25, 1996. The meeting was entitled The Cellular Basis of Cardiovascular Function in Health and Disease. There were over 40 invited speakers from 15 different countries represented at the meeting, attended by over 280 people. Keynote lectures were presented by Drs. Norman Alpert (Burlington, VT), Robert Jennings (Chapel Hill, NC), Makoto Nagano (Tokyo, Japan), Howard Morgan (Danville, PA), John Solaro (Chicago, IL) and Nobuskira Takeda (Tokyo, Japan). Dr. Henry Friesen, President of the Medical Research Council of Canada, presented Dr. Dhalla with a plaque at the banquet honouring his research accomplishments over his distinguished career. Dr. Dhalla's outstanding research achievements in understanding the subcellular basis of cardiovascular disease were highlighted at the meeting. One of the unique aspects of the meeting was the special effort made by 39 former trainees of Dr. Dhalla to attend the meeting to honour their mentor. The ex-students and trainees came from all over Canada, the United States, Japan, Slovakia, Germany, the Czech Republic, Estonia and the Netherlands. The meeting was judged to be an overwhelming success in terms of the scientific content as well as collaborative interactions initiated.

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