doves diplomats and diabetes a darwinian interpretation of type 2 diabetes and related disorders

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Doves Diplomats And Diabetes

Author : Milind Watve
ISBN : 9781461444091
Genre : Science
File Size : 57. 13 MB
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Darwinian medicine looks at the ecological and evolutionary roots of disease. A disease is an interaction between a genome and its biotic or abiotic environment and therefore a disease is essentially an ecological process. Good understanding of ecology and a Darwinian way of thinking can give us novel and useful perspectives on health and disease. If we understand the disease process better, we can certainly prevent, control as well as treat diseases in a better way. Although the thought that the origins of obesity and type 2 diabetes (T2D) might lie in our hunter gatherer adaptations is not new, research over the last decade makes us rethink many of the classical concepts. Brain and behavior is increasingly being recognized as central to all the endocrine, metabolic and immunological changes that earmark type 2 diabetes and other metabolic syndrome disorders. A major change in paradigm appears to be on the horizon and the proposed book intends to speed up the paradigm shift by raising important questions, pointing out flaws and inadequacies in the prevalent paradigm and stimulating radical rethinking which would redirect and refine the line of research as well as bring some fundamental changes in drug discovery and clinical practice. ​

Disease Modelling And Public Health

Author :
ISBN : 9780444639691
Genre : Mathematics
File Size : 66. 52 MB
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Disease Modelling and Public Health, Part A, Volume 36 addresses new challenges in existing and emerging diseases with a variety of comprehensive chapters that cover Infectious Disease Modeling, Bayesian Disease Mapping for Public Health, Real time estimation of the case fatality ratio and risk factor of death, Alternative Sampling Designs for Time-To-Event Data with Applications to Biomarker Discovery in Alzheimer's Disease, Dynamic risk prediction for cardiovascular disease: An illustration using the ARIC Study, Theoretical advances in type 2 diabetes, Finite Mixture Models in Biostatistics, and Models of Individual and Collective Behavior for Public Health Epidemiology. As a two part volume, the series covers an extensive range of techniques in the field. It present a vital resource for statisticians who need to access a number of different methods for assessing epidemic spread in population, or in formulating public health policy. Presents a comprehensive, two-part volume written by leading subject experts Provides a unique breadth and depth of content coverage Addresses the most cutting-edge developments in the field Includes chapters on Ebola and the Zika virus; topics which have grown in prominence and scholarly output

Adipose Tissue Biology

Author : Michael E. Symonds
ISBN : 9783319520315
Genre : Medical
File Size : 83. 18 MB
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The past decade has seen an exponential increase in our knowledge and understanding of adipose tissue biology. This has coincided with the continued rise in obesity across all generations. Clearly despite substantial advances in research into adipose tissue this still has had limited impact on the on-going obesity epidemic across a majority of countries in the world. This book brings together many leading experts in the field to provide an up to date and comprehensive review of the key aspects of adipose tissue. It therefore includes chapters on evolution, development and inflammation together with a detailed review of brown and beige adipose tissue biology and their potential significance in preventing or combating obesity. These chapters are complemented by those on genetics and gender influences, together with nutrition through the life cycle. Ultimately the book provides an overview of the complexities of adipose tissue biology and the continuing challenge to combat obesity in the 21st century.

The Metabolic Ghetto

Author : Jonathan C. K. Wells
ISBN : 9781316679364
Genre : Science
File Size : 78. 99 MB
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Chronic diseases have rapidly become the leading global cause of morbidity and mortality, yet there is poor understanding of this transition, or why particular social and ethnic groups are especially susceptible. In this book, Wells adopts a multidisciplinary approach to human nutrition, emphasising how power relations shape the physiological pathways to obesity, diabetes, hypertension and cardiovascular disease. Part I reviews the physiological basis of chronic diseases, presenting a 'capacity-load' model that integrates the nutritional contributions of developmental experience and adult lifestyle. Part II presents an evolutionary perspective on the sensitivity of human metabolism to ecological stresses, highlighting how social hierarchy impacts metabolism on an intergenerational timescale. Part III reviews how nutrition has changed over time, as societies evolved and coalesced towards a single global economic system. Part IV integrates these physiological, evolutionary and politico-economic perspectives in a unifying framework, to deepen our understanding of the societal basis of metabolic ill-health.

Bridging The Communication Gap In Science And Technology

Author : Pallava Bagla
ISBN : 9789811010255
Genre : Language Arts & Disciplines
File Size : 71. 45 MB
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This first-of-a-kind volume provides a snapshot of existing science communication policy and practice in India across different S&T sectors, and offers solutions to building effective communication. It provides an understanding on how to avoid societal clashes in situations when science meets the public in these sectors. The editors and contributors argue that effective S&T communication leads not only to a more informed public but also benefits research itself, and in a changing society like India this is a crucial element related to good governance and policy making. In this volume, experienced masters of the craft provide practical solutions to making S&T communication more effective in a vast democracy like India, which has complex issues related to literacy levels, diverse languages, varying political will, reach, and resources. Through, discussions on cases of creating information modules for the public on the Internet, television and radio, social media, as well as traditional ways of outreach like people’s science movements, holding popular science events, and fairs, the volume provides highly valuable directions on how developing countries with low resources and complex populations can communicate S&T research to the public and bridge communication gaps. This volume will interest researchers from science, social science, mass communication and public relations departments, journalists, as well as practitioners and policy makers from government and non-government institutions involved in S&T policy, practice and communication and people who want to understand the complex S&T landscape of India.

A Short History Of Nearly Everything

Author : Bill Bryson
ISBN : 9780385674508
Genre : Science
File Size : 71. 56 MB
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One of the world’s most beloved and bestselling writers takes his ultimate journey -- into the most intriguing and intractable questions that science seeks to answer. In A Walk in the Woods, Bill Bryson trekked the Appalachian Trail -- well, most of it. In In A Sunburned Country, he confronted some of the most lethal wildlife Australia has to offer. Now, in his biggest book, he confronts his greatest challenge: to understand -- and, if possible, answer -- the oldest, biggest questions we have posed about the universe and ourselves. Taking as territory everything from the Big Bang to the rise of civilization, Bryson seeks to understand how we got from there being nothing at all to there being us. To that end, he has attached himself to a host of the world’s most advanced (and often obsessed) archaeologists, anthropologists, and mathematicians, travelling to their offices, laboratories, and field camps. He has read (or tried to read) their books, pestered them with questions, apprenticed himself to their powerful minds. A Short History of Nearly Everything is the record of this quest, and it is a sometimes profound, sometimes funny, and always supremely clear and entertaining adventure in the realms of human knowledge, as only Bill Bryson can render it. Science has never been more involving or entertaining. From the Hardcover edition.

The Rise Of David Levinsky

Author : Abraham Cahan
ISBN : NYPL:33433111598847
Genre : Assimilation (Sociology)
File Size : 39. 85 MB
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Spontaneous Evolution

Author : Bruce H. Lipton
ISBN : 9781458755629
Genre :
File Size : 90. 52 MB
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We've all heard stories of people who've experienced seemingly miraculous recoveries from illness, but can the same thing happen for our world? According to pioneering biologist Bruce H. Lipton, it's not only possible, it's already occurring. In Spontaneous Evolution, this world-renowned expert in the emerging science of epigenetics reveals how our changing understanding of biology will help us navigate this turbulent period in our planet's history and how each of us can participate in this global shift. In collaboration with political philosopher Steve Bhaerman, Dr. Lipton invites readers to reconsider: the ''unquestionable'' pillars of biology, including random evolution, survival of the fittest, and the role of DNA; the relationship between mind and matter; how our beliefs about nature and human nature shape our politics, culture, and individual lives; and how each of us can become planetary ''stem cells'' supporting the health and growth of our world. By questioning the old beliefs that got us to where we are today and keep us stuck in the status quo, we can trigger the spontaneous evolution of our species that will usher in a brighter future.

Signal Transduction Mechanisms

Author : J.A. Barnes
ISBN : 9781461520153
Genre : Science
File Size : 22. 27 MB
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This volume contains the proceedings of an International Symposium on `Second Messenger Systems - Molecular, Cellular and Behavioural Aspects', which was held at Tobago on June 16-17, 1994. The interaction of an extracellular agonist (First Messenger) with its plasma membrane receptor leads to the transmission of a signal across the cell membrane and results in the production and/or activation of other signalling molecules (Second Messengers). These Second Messengers control the action of many protein kinases and protein phosphatases and so lead to cellular responses. Although the biochemical basis of the transduction of signals in the main signalling systems in eukaryotic cells is probably largely known, intensified research is ongoing in the following areas: the discovery of specific substrates for many protein kinases, elucidation of the biological significance of the differential tissue expression and heterogeneity of many signalling proteins, and the unravelling of diverse interactions (such as signal potentiation, synergism, antagonism and neuronal co-transmission) between signalling systems. As knowledge from such studies accumulates, it is becoming clear that the `cross talk' interactions between signalling systems are important features of dynamic cell regulation. This volume is designed to summarize some aspects of the current work on various Second Messenger Systems and the integration of signals with respect to plasma membrane receptors. Second Messenger generation and degradation, protein kinase and phosphatase, cell cycle control, and cellular learning and memory.

The God Part Of The Brain

Author : Matthew Alper
ISBN : 9781402236372
Genre : Science
File Size : 23. 49 MB
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Is Man the product of a God...or is "God" the product of human evolution? From the dawn of our species, every human culture-no matter how isolated-has believed in some form of a spiritual realm. According to author Matthew Alper, this is no mere coincidence but rather due to the fact that humans, as a species, are genetically predisposed to believe in the universal concepts of a god, a soul and an afterlife. This instinct to believe is the result of an evolutionary adaptation-a coping mechanism-that emerged in our species to help us survive our unique and otherwise debilitating awareness of death. Spiritual seekers and atheists alike will be compelled and transformed by Matthew Alper's classic study of science and religion. The 'God' Part of the Brain has gained critical acclaim from some of the world's leading scientists, secular humanists, and theologians, and is as a must read for anyone who has pondered the question of God's existence, as well as the meaning of our own. Praise for The "God" Part of the Brain "This cult classic in many ways parallels Rene Descartes' search for reliable and certain knowledge...Drawing on such disciplines as philosophy, psychology, and biology, Alper argues that belief in a spiritual realm is an evolutionary coping method that developed to help humankind deal with the fear of death...Highly recommended."— Library Journal "I very much enjoyed the account of your spiritual journey and believe it would make excellent reading for every college student - the resultant residence-hall debates would be the best part of their education. It often occurs to me that if, against all odds, there is a judgmental God and heaven, it will come to pass that when the pearly gates open, those who had the valor to think for themselves will be escorted to the head of the line, garlanded, and given their own personal audience." — Edward O. Wilson, two-time Pulitzer Prize-Winner "This is an essential book for those in search of a scientific understanding of man's spiritual nature. Matthew Alper navigates the reader through a labyrinth of intriguing questions and then offers undoubtedly clear answers that lead to a better understanding of our objective reality." — Elena Rusyn, MD, PhD; Gray Laboratory; Harvard Medical School "What a wonderful book you have written. It was not only brilliant and provocative but also revolutionary in its approach to spirituality as an inherited trait."— Arnold Sadwin, MD, former chief of Neuropsychiatry at the University of Pennsylvania "A lively manifesto...For the discipline's specific application to the matter at hand, I've seen nothing that matches the fury of The 'God' Part of the Brain, which perhaps explains why it's earned something of a cult following." — Salon.com "All 6 billion plus inhabitants of Earth should be in possession of this book. Alper's tome should be placed in the sacred writings' section of libraries, bookstores, and dwellings throughout the world. Matthew Alper is the new Galileo...Immensely important...Defines in a clear and concise manner what each of us already knew but were afraid to admit and exclaim."— John Scoggins, PhD "Vibrant ... vivacious. An entertaining and provocative introduction to speculations concerning the neural basis of spirituality."— Free Inquiry Magazine

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