development of the ocular lens

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Development Of The Ocular Lens

Author : Frank J. Lovicu
ISBN : 0521838193
Genre : Medical
File Size : 55. 92 MB
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This book provides a comprehensive view of research in lens developmental biology, emphasising technical and molecular breakthroughs. Elucidation of the mechanisms that govern lens development has enabled us to understand how the normal lens forms and how developmental processes are involved in the maintenance of its normal structure, function and growth throughout life. This knowledge is fundamental to our understanding of many lens disorders. The ocular lens has also become a model for understanding the developmental biology of more complex organ systems. In this 2004 book, leading experts in lens cell biology and development discuss lens evolution, induction, morphology, the regulation of the lens cell cycle and fiber cell differentiation, as well as lens regeneration. This book is an authoritative treatment of the subject that will serve as a reference for graduate students and research scientists in developmental biology and in the visual sciences, as well as for ophthalmologists.

Chromatin Remodeling Atpases Brg1 And Snf2h In Ocular Lens Development

Author : Shuying He
ISBN : OCLC:844203511
Genre :
File Size : 71. 57 MB
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Development Of The Visual System

Author : S.P. Bhat
ISBN : 9783805578714
Genre : Medical
File Size : 66. 82 MB
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All the tissues of the eye, including the lens, the cornea, the ciliary body, the neuroretina and the retinal pigment epithelium must work in harmony for the realization of clear vision.The phenotypic emergence of each of these tissues requires intercellular communication, which is achieved through direct physical contact as well as through diffusion and reception of the molecular beacons.This volume provides an overview of the molecular and cellular biology of eye development and encompasses themes like early gene expression in the surface ectoderm and the optic cup, retinal neurogenesis, signaling molecules and axonal guidance. It presents new findings on the influence of the lens on the development of the visual system and how gene expression in the optic cup controls differentiation of the lens fiber cell while established ideas about the morphogenesis of the ciliary body are challenged. A valuable source of information for developmental biologists and neurobiologists as well as ophthalmologists interested in understanding the relationship between temporally and spatially regulated gene activity and function and cellular interactions in early development and neuronal functions.

Cellular Communication During Ocular Development

Author : J. B. Sheffield
ISBN : 9781461257646
Genre : Science
File Size : 64. 66 MB
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The eye has fascinated scientists from the earliest days of biological investigation. The diversity of its parts and the precision of their interac tion make it a favorite model system for a variety of developmental studies. The eye is a particularly valuable experimental system not only because its tissues provide examples of fundamental processes. but also because it is a prominent and easily accessible structure at very early embryonic ages. In order to provide an open forum for investigators working on all aspects of ocular development. a series of symposia on ocular and visual development was initiated in 1973. A major objective of the symposia has been to foster communication between the basic research worker and the clinical community. It is our feeling that much can be learned on both sides from this interaction. The idea for an informal meeting allowing maximum exchange of ideas originated with Dr. Leon Canbeub. who supplied the necessary driving force that made the series a reality. Each symposium has concentrated on a different aspect of ocular development. Speakers have been selected to approach related topics from different perspec tives.

Ocular Size And Shape Regulation During Development

Author : S.R. Hilfer
ISBN : 9781461259640
Genre : Science
File Size : 24. 35 MB
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The eye has fascinated scientists from the earliest days of biological investigation. The diversity of its parts and the precision of their interac tion make it a favorite model system for a variety of developmental studies. The eye is a particularly valuable experimental system not only because its tissues provide examples of fundamental processes, but also because it is a prominent and easily accessible structure at very early embryonic ages. In order to provide an open forum for investigators working on all aspects of ocular development, a series of symposia on ocular and visual de velopment was initiated in 1973. A second purpose has been to foster communication between the basic research worker and the clinical community. It is our feeling that much can be learned on both sides from this interaction. The idea for an informal meeting allowing a maximum exchange of ideas originated with Dr. Leon Candeub, who supplied the necessary driving force that made the series a reality.

Cell Biology Of The Eye

Author : David Mcdevitt
ISBN : 9780323145213
Genre : Nature
File Size : 56. 9 MB
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Cell Biology of the Eye discusses the eye tissues and its role in the investigations on active transport, growth factors, receptors, and differentiation. The book is comprised of articles which discuss corneal proteoglycans; transport of ions and metabolites across the corneal endothelium; the ontogeny and localization of the crystallins in eye lens development and regeneration; the biological-physical basis of lens transparency; the chromatic organization of the retina; and the dopamine neurons in the retina. This treatise will serve as a valuable reference text for graduate and professional students, teachers, researchers, clinicians, and to all in the vision field.

Optical Design Of Microscopes

Author : George Seward
ISBN : 0819480959
Genre : Science
File Size : 88. 93 MB
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Knowledge of microscope design is rapidly becoming more important. Microscopes are used in critical applications such as drug development, clinical tests, and genomics. Considerable expertise is required for the evaluation, design, and manufacture of these instruments. Several subsystems must be integrated: the source, the illumination optics, the specimen, the objective lens, the tube optics, and the sensor. The large numerical aperture of a microscope is essential for small spot size and high brightness; however, the large numerical aperture also presents difficult issues in optical design and fabrication. This book provides a foundation for developing design expertise through education, practice, and exploration. It is suitable for lens designers, optical engineers, and students with a basic knowledge of microscope structure.

The Ocular Lens

Author : Harry Maisel
ISBN : 0824772970
Genre : Medical
File Size : 62. 63 MB
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Animal Models In Eye Research

Author :
ISBN : 0080921035
Genre : Science
File Size : 52. 99 MB
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The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease. * Presents information on the major animal models used in eye research including invertebrates and vertebrates * Provides researchers with information needed to choose between model organisms * Includes an introductory chapter on the different types of eyes, stressing possible common molecular machinery

Ocular Theraputics And Drug Delivery

Author : Indra K. Reddy
ISBN : 1566762138
Genre : Medical
File Size : 59. 46 MB
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Since ocular therapeutics and drug delivery is a subject of interest to specialists from various disciplines such as chemical, biochemical, medical, pharmaceutical, and toxicological, it truly presents a unique situation requiring a multi-disciplinary approach in understanding and addressing various problems. Yet we see that scientists associated with these areas are working, by and large, independently of one another, thus limiting dissemination of knowledge, experience and ideas that would greatly enhance the overall progress in this area of research. Regrettably, the information currently available in ocular therapeutics and drug delivery, though extensive, is still fragmented into various disciplines making meaningful synthesis difficult. Several books are available that cover one or two aspects of the multi-disciplinary fields on an individual basis; however, none is available that covers all of them. The chapters contained in this book are specific to various interrelated areas of ocular therapeutics and drug delivery and are written by acknowledged experts from both academia and industry. The book itself is divided into five parts, namely: (I) overview,basic principles, and methodology; (II) pathopharmacology and clinical applications; (III) chemical/ biochemical approaches to ocular drug delivery; (IV) formulation and drug delivery considerations; and (V) industrial and regulatory considerations. Individual chapters in each section, apart from presenting a concise text, entail an extensive listing of references.

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