development of innovative drugs via modeling with matlab a practical guide

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Development Of Innovative Drugs Via Modeling With Matlab

Author : Ronald Gieschke
ISBN : 9783642397653
Genre : Medical
File Size : 26. 17 MB
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The development of innovative drugs is becoming more difficult while relying on empirical approaches. This inspired all major pharmaceutical companies to pursue alternative model-based paradigms. The key question is: How to find innovative compounds and, subsequently, appropriate dosage regimens? Written from the industry perspective and based on many years of experience, this book offers: - Concepts for creation of drug-disease models, introduced and supplemented with extensive MATLAB programs - Guidance for exploration and modification of these programs to enhance the understanding of key principles - Usage of differential equations to pharmacokinetic, pharmacodynamic and (patho-) physiologic problems thereby acknowledging their dynamic nature - A range of topics from single exponential decay to adaptive dosing, from single subject exploration to clinical trial simulation, and from empirical to mechanistic disease modeling. Students with an undergraduate mathematical background or equivalent education, interest in life sciences and skills in a high-level programming language such as MATLAB, are encouraged to engage in model-based pharmaceutical research and development.

Dissertation Abstracts International

Author :
ISBN : STANFORD:36105121673151
Genre : Science
File Size : 62. 15 MB
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Data Mining

Author : Ian H. Witten
ISBN : 3446215336
Genre :
File Size : 74. 31 MB
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The British National Bibliography

Author : Arthur James Wells
ISBN : STANFORD:36105211722678
Genre : English literature
File Size : 51. 80 MB
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Operations Research And Health Care

Author : Margaret L. Brandeau
ISBN : 9781402080661
Genre : Medical
File Size : 23. 35 MB
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In both rich and poor nations, public resources for health care are inadequate to meet demand. Policy makers and health care providers must determine how to provide the most effective health care to citizens using the limited resources that are available. This chapter describes current and future challenges in the delivery of health care, and outlines the role that operations research (OR) models can play in helping to solve those problems. The chapter concludes with an overview of this book – its intended audience, the areas covered, and a description of the subsequent chapters. KEY WORDS Health care delivery, Health care planning HEALTH CARE DELIVERY: PROBLEMS AND CHALLENGES 3 1.1 WORLDWIDE HEALTH: THE PAST 50 YEARS Human health has improved significantly in the last 50 years. In 1950, global life expectancy was 46 years [1]. That figure rose to 61 years by 1980 and to 67 years by 1998 [2]. Much of these gains occurred in low- and middle-income countries, and were due in large part to improved nutrition and sanitation, medical innovations, and improvements in public health infrastructure.

International Books In Print

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ISBN : UOM:39015046822667
Genre : English imprints
File Size : 62. 25 MB
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6th International Conference On The Development Of Biomedical Engineering In Vietnam Bme6

Author : Toi Vo Van
ISBN : 9789811043611
Genre : Technology & Engineering
File Size : 46. 2 MB
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Under the motto “Healthcare Technology for Developing Countries” this book publishes many topics which are crucial for the health care systems in upcoming countries. The topics include Cyber Medical Systems Medical Instrumentation Nanomedicine and Drug Delivery Systems Public Health Entrepreneurship This proceedings volume offers the scientific results of the 6th International Conference on the Development of Biomedical Engineering in Vietnam, held in June 2016 at Ho Chi Minh City.

The University Of Virginia Record

Author : University of Virginia
ISBN : UVA:X030050610
Genre : Biography & Autobiography
File Size : 58. 84 MB
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Cumulated Index Medicus

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ISBN : UIUC:30112023523266
Genre : Medicine
File Size : 46. 97 MB
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Der Gleichl Ufige Doppelschneckenextruder

Author : Klemens Kohlgrüber
ISBN : 9783446452350
Genre : Technology & Engineering
File Size : 54. 92 MB
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Alles zum gleichläufigen Doppelschneckenextruder Bei der Herstellung von Kunststoffen, insbesondere bei der Aufbereitung und Verarbeitung bis zum Fertigprodukt werden Extruder eingesetzt, wobei der gleichläufige Doppelschneckenextruder eine dominante Rolle spielt. Aber auch in anderen Industriezweigen, z. B. der Kautschuk- und Lebensmittelindustrie und zunehmend in der Pharmaindustrie kommen die Gleichdrallschnecken vielfältig zum Einsatz. Eine multifunktionale Maschine Das Fachbuch gibt umfassenden Einblick in die verfahrens- und maschinentechnischen Grundlagen und legt großen Fokus auf Praxisbeispiele. Meist sind die Schnecken modular aufgebaut und können damit sehr flexibel an veränderte Aufgabenstellung und Produkteigenschaften angepasst werden. Für die optimale Auslegung eines Doppelschneckenextruders sind vertiefte Kenntnisse über die Maschine und den Prozess erforderlich. Ein Praxisbuch für Einsteiger und Profis Die zweite Auflage entstand unter Mitwirkung vieler Fachautoren von renommierten Firmen und Hochschulen. Alle inzwischen erfolgten Weiterentwicklungen wurden berücksichtigt. Die zweite Auflage wurde durchgehend neu bearbeitet, ist deutlich erweitert, komplett in Farbe und in neuem Layout. Mit Zusatzmaterial auf der Website des Herausgebers: Videos, Bilder, Beispiel-Aufgaben, Rechentools EXTRA: E-Book inside

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