design and analysis of experiments classical and regression approaches with sas statistics a series of textbooks and monographs

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Design And Analysis Of Experiments

Author : Leonard C. Onyiah
ISBN : 9781420060553
Genre : Mathematics
File Size : 33. 32 MB
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Unlike other books on the modeling and analysis of experimental data, Design and Analysis of Experiments: Classical and Regression Approaches with SAS not only covers classical experimental design theory, it also explores regression approaches. Capitalizing on the availability of cutting-edge software, the author uses both manual methods and SAS programs to carry out analyses. The book presents most of the different designs covered in a typical experimental design course. It discusses the requirements for good experimentation, the completely randomized design, the use of orthogonal contrast to test hypotheses, and the model adequacy check. With an emphasis on two-factor factorial experiments, the author analyzes repeated measures as well as fixed, random, and mixed effects models. He also describes designs with randomization restrictions, before delving into the special cases of the 2k and 3k factorial designs, including fractional replication and confounding. In addition, the book covers response surfaces, balanced incomplete block and hierarchical designs, ANOVA, ANCOVA, and MANOVA. Fortifying the theory and computations with practical exercises and supplemental material, this distinctive text provides a modern, comprehensive treatment of experimental design and analysis.

Applied Time Series Analysis

Author : Wayne A. Woodward
ISBN : 9781439818374
Genre : Mathematics
File Size : 54. 28 MB
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Virtually any random process developing chronologically can be viewed as a time series. In economics, closing prices of stocks, the cost of money, the jobless rate, and retail sales are just a few examples of many. Developed from course notes and extensively classroom-tested, Applied Time Series Analysis includes examples across a variety of fields, develops theory, and provides software to address time series problems in a broad spectrum of fields. The authors organize the information in such a format that graduate students in applied science, statistics, and economics can satisfactorily navigate their way through the book while maintaining mathematical rigor. One of the unique features of Applied Time Series Analysis is the associated software, GW-WINKS, designed to help students easily generate realizations from models and explore the associated model and data characteristics. The text explores many important new methodologies that have developed in time series, such as ARCH and GARCH processes, time varying frequencies (TVF), wavelets, and more. Other programs (some written in R and some requiring S-plus) are available on an associated website for performing computations related to the material in the final four chapters.

Advanced Risk Analysis In Engineering Enterprise Systems

Author : Cesar Ariel Pinto
ISBN : 9781439826157
Genre : Business & Economics
File Size : 34. 42 MB
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Since the emerging discipline of engineering enterprise systems extends traditional systems engineering to develop webs of systems and systems-of-systems, the engineering management and management science communities need new approaches for analyzing and managing risk in engineering enterprise systems. Advanced Risk Analysis in Engineering Enterprise Systems presents innovative methods to address these needs. With a focus on engineering management, the book explains how to represent, model, and measure risk in large-scale, complex systems that are engineered to function in enterprise-wide environments. Along with an analytical framework and computational model, the authors introduce new protocols: the risk co-relationship (RCR) index and the functional dependency network analysis (FDNA) approach. These protocols capture dependency risks and risk co-relationships that may exist in an enterprise. Moving on to extreme and rare event risks, the text discusses how uncertainties in system behavior are intensified in highly networked, globally connected environments. It also describes how the risk of extreme latencies in delivering time-critical data, applications, or services can have catastrophic consequences and explains how to avoid these events. With more and more communication, transportation, and financial systems connected across domains and interfaced with an infinite number of users, information repositories, applications, and services, there has never been a greater need for analyzing risk in engineering enterprise systems. This book gives you advanced methods for tackling risk problems at the enterprise level.

Optimum Experimental Designs With Sas

Author : Anthony Atkinson
ISBN : 9780199296590
Genre : Business & Economics
File Size : 90. 88 MB
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Experiments in the field and in the laboratory cannot avoid random error and statistical methods are essential for their efficient design and analysis. Authored by leading experts in key fields, this text provides many examples of SAS code, results, plots and tables, along with a fully supported website.

Statistical Methods For The Analysis Of Repeated Measurements

Author : Charles S. Davis
ISBN : 9780387215730
Genre : Mathematics
File Size : 78. 88 MB
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A comprehensive introduction to a wide variety of statistical methods for the analysis of repeated measurements. It is designed to be both a useful reference for practitioners and a textbook for a graduate-level course focused on methods for the analysis of repeated measurements. The important features of this book include a comprehensive coverage of classical and recent methods for continuous and categorical outcome variables; numerous homework problems at the end of each chapter; and the extensive use of real data sets in examples and homework problems.

Missing Data Analysis In Practice

Author : Trivellore Raghunathan
ISBN : 9781482211931
Genre : Mathematics
File Size : 45. 16 MB
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Missing Data Analysis in Practice provides practical methods for analyzing missing data along with the heuristic reasoning for understanding the theoretical underpinnings. Drawing on his 25 years of experience researching, teaching, and consulting in quantitative areas, the author presents both frequentist and Bayesian perspectives. He describes easy-to-implement approaches, the underlying assumptions, and practical means for assessing these assumptions. Actual and simulated data sets illustrate important concepts, with the data sets and codes available online. The book underscores the development of missing data methods and their adaptation to practical problems. It mainly focuses on the traditional missing data problem. The author also shows how to use the missing data framework in many other statistical problems, such as measurement error, finite population inference, disclosure limitation, combing information from multiple data sources, and causal inference.

Modern Approaches To Clinical Trials Using Sas Classical Adaptive And Bayesian Methods

Author : Sandeep Menon
ISBN : 9781629600826
Genre : Mathematics
File Size : 55. 31 MB
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Get the tools you need to use SAS® in clinical trial design! Unique and multifaceted, Modern Approaches to Clinical Trials Using SAS: Classical, Adaptive, and Bayesian Methods, edited by Sandeep M. Menon and Richard C. Zink, thoroughly covers several domains of modern clinical trial design: classical, group sequential, adaptive, and Bayesian methods that are applicable to and widely used in various phases of pharmaceutical development. Written for biostatisticians, pharmacometricians, clinical developers, and statistical programmers involved in the design, analysis, and interpretation of clinical trials, as well as students in graduate and postgraduate programs in statistics or biostatistics, the book touches on a wide variety of topics, including dose-response and dose-escalation designs; sequential methods to stop trials early for overwhelming efficacy, safety, or futility; Bayesian designs that incorporate historical data; adaptive sample size re-estimation; adaptive randomization to allocate subjects to more effective treatments; and population enrichment designs. Methods are illustrated using clinical trials from diverse therapeutic areas, including dermatology, endocrinology, infectious disease, neurology, oncology, and rheumatology. Individual chapters are authored by renowned contributors, experts, and key opinion leaders from the pharmaceutical/medical device industry or academia. Numerous real-world examples and sample SAS code enable users to readily apply novel clinical trial design and analysis methodologies in practice.

Generalized Linear Models

Author : Raymond H. Myers
ISBN : 9780470556979
Genre : Mathematics
File Size : 22. 33 MB
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Praise for the First Edition "The obvious enthusiasm of Myers, Montgomery, and Vining and their reliance on their many examples as a major focus of their pedagogy make Generalized Linear Models a joy to read. Every statistician working in any area of applied science should buy it and experience the excitement of these new approaches to familiar activities." —Technometrics Generalized Linear Models: With Applications in Engineering and the Sciences, Second Edition continues to provide a clear introduction to the theoretical foundations and key applications of generalized linear models (GLMs). Maintaining the same nontechnical approach as its predecessor, this update has been thoroughly extended to include the latest developments, relevant computational approaches, and modern examples from the fields of engineering and physical sciences. This new edition maintains its accessible approach to the topic by reviewing the various types of problems that support the use of GLMs and providing an overview of the basic, related concepts such as multiple linear regression, nonlinear regression, least squares, and the maximum likelihood estimation procedure. Incorporating the latest developments, new features of this Second Edition include: A new chapter on random effects and designs for GLMs A thoroughly revised chapter on logistic and Poisson regression, now with additional results on goodness of fit testing, nominal and ordinal responses, and overdispersion A new emphasis on GLM design, with added sections on designs for regression models and optimal designs for nonlinear regression models Expanded discussion of weighted least squares, including examples that illustrate how to estimate the weights Illustrations of R code to perform GLM analysis The authors demonstrate the diverse applications of GLMs through numerous examples, from classical applications in the fields of biology and biopharmaceuticals to more modern examples related to engineering and quality assurance. The Second Edition has been designed to demonstrate the growing computational nature of GLMs, as SAS®, Minitab®, JMP®, and R software packages are used throughout the book to demonstrate fitting and analysis of generalized linear models, perform inference, and conduct diagnostic checking. Numerous figures and screen shots illustrating computer output are provided, and a related FTP site houses supplementary material, including computer commands and additional data sets. Generalized Linear Models, Second Edition is an excellent book for courses on regression analysis and regression modeling at the upper-undergraduate and graduate level. It also serves as a valuable reference for engineers, scientists, and statisticians who must understand and apply GLMs in their work.

Design And Analysis Of Cross Over Trials Third Edition

Author : Byron Jones
ISBN : 9781439861424
Genre : Mathematics
File Size : 25. 72 MB
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Design and Analysis of Cross-Over Trials is concerned with a specific kind of comparative trial known as the cross-over trial, in which subjects receive different sequences of treatments. Such trials are widely used in clinical and medical research, and in other diverse areas such as veterinary science, psychology, sports science, and agriculture. The first edition of this book was the first to be wholly devoted to the subject. The second edition was revised to mirror growth and development in areas where the design remained in widespread use and new areas where it had grown in importance. This new Third Edition: Contains seven new chapters written in the form of short case studies that address re-estimating sample size when testing for average bioequivalence, fitting a nonlinear dose response function, estimating a dose to take forward from phase two to phase three, establishing proof of concept, and recalculating the sample size using conditional power Employs the R package Crossover, specially created to accompany the book and provide a graphical user interface for locating designs in a large catalog and for searching for new designs Includes updates regarding the use of period baselines and the analysis of data from very small trials Reflects the availability of new procedures in SAS, particularly proc glimmix Presents the SAS procedure proc mcmc as an alternative to WinBUGS for Bayesian analysis Complete with real data and downloadable SAS code, Design and Analysis of Cross-Over Trials, Third Edition provides a practical understanding of the latest methods along with the necessary tools for implementation.

Design And Analysis Of Group Randomized Trials

Author : David M. Murray
ISBN : 9780195120363
Genre : Medical
File Size : 81. 28 MB
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This text provides the most comprehensive treatment of the design and analytic issues involved in group-randomized trials. GRTs are comparative studies conducted to evaluate the effect of a health promotion intervention in which the units of assignment are identifiable groups (e.g., schools, worksites) and the units of observation are members of those groups (e.g., students, workers). The book reviews the underlying issues, the most widely used research designs, and analytic strategies. There is an emphasis on mixed-model regression, with two chapters illustrating the analytic methods in SAS PROC MIXED and GLIMMIX. There is also a detailed chapter on power analysis and sample size calculation.

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