dendritic cell interactions with bacteria advances in molecular and cellular microbiology

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Dendritic Cell Interactions With Bacteria Advances In Molecular And Cellular Microbiology

Author : Maria Rescigno
ISBN : 0511296282
Genre : MEDICAL
File Size : 81. 89 MB
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Emerging evidence suggests that dendritic cells play a major role in the orchestration of the immune response to bacteria. This volume introduces the reader to the complex world of dendritic cells and describes how the intimate interplay between dendritic cells, bacteria and the environment dictates either the induction of immunity or tolerance to the encountered microorganisms. It discusses how this can allow organisms to tolerate beneficial bacteria and to react against pathogens, as well as the strategies pathogenic bacteria have evolved to escape dendritic cell patrolling. Expert contributors discuss everything from bacterial capture and recognition to their killing, processing and the induction of adaptive immunity. Particular focus is on the tissue context in which bacteria are handled by dendritic cells and on possible defects therein, which may potentially lead to chronic infection or inflammation. Graduate students and researchers will find this an invaluable overview of current dendritic cell biology research.

Dendritic Cell Interactions With Bacteria

Author : Maria Rescigno
ISBN : 9781139462365
Genre : Science
File Size : 53. 35 MB
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Emerging evidence suggests that dendritic cells play a major role in the orchestration of the immune response to bacteria. This volume introduces the reader to the complex world of dendritic cells and describes how the intimate interplay between dendritic cells, bacteria and the environment dictates either the induction of immunity or tolerance to the encountered microorganisms. It discusses how this can allow organisms to tolerate beneficial bacteria and to react against pathogens, as well as the strategies pathogenic bacteria have evolved to escape dendritic cell patrolling. Expert contributors discuss everything from bacterial capture and recognition to their killing, processing and the induction of adaptive immunity. Particular focus is on the tissue context in which bacteria are handled by dendritic cells and on possible defects therein, which may potentially lead to chronic infection or inflammation. Graduate students and researchers will find this an invaluable overview of current dendritic cell biology research.

Advances In Molecular Biophotonics

Author : Yong Deng
ISBN : 9783110304596
Genre : Science
File Size : 20. 20 MB
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Being the most active field in modern physics, Optical Physics has developed many new branches and interdisciplinary fields overlapping with various classical disciplines. This series summarizes the advancements of optical physics in the past twenty years in the following fields: High Field Laser Physics, Precision Laser Spectroscopy, Nonlinear Optics, Nanophotonics, Quantum Optics, Ultrafast Optics, Condensed Matter Optics, and Molecular Biophotonics.

Salmonella Infections

Author : Pietro Mastroeni
ISBN : 0521835046
Genre : Medical
File Size : 84. 30 MB
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Salmonella enterica encompasses a diverse range of bacteria that cause a spectrum of diseases in many hosts. Advancements in prevention and treatment of S. enterica infections have at times been hampered by compartmentalization of research efforts and lack of multidisciplinary approaches. This book attempts to cover a diverse range of topics related to the biology of S. enterica infections, including epidemiological and clinical aspects, molecular pathogenesis, immunity to disease and vaccines. S. enterica infections are important zoonoses and therefore material on infections of animals and public health issues have also been considered. Each chapter can be read independently, but the full contents of the book will provide the reader with up-to-date knowledge on all the key aspects of salmonellosis in humans and animals. It will therefore be of interest to graduate students and researchers, as well as to clinicians, whose research focuses on this important pathogen.

The Human Microbiota And Microbiome

Author : Julian R Marchesi
ISBN : 9781780640495
Genre : Medical
File Size : 85. 80 MB
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Thousands of different microbial species colonize the human body, and are essential for our survival. This book presents a review of the current understanding of human microbiomes, the functions that they bring to the host, how we can model them, their role in health and disease and the methods used to explore them. Current research into areas such as the long-term effect of antibiotics makes this a subject of considerable interest. This title is essential reading for researchers and students of microbiology.

Bacterial Evasion Of Host Immune Responses

Author : Brian Henderson
ISBN : 0521801737
Genre : Medical
File Size : 56. 99 MB
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Comprehensive review of current research concerning how bacteria evade immunity and hence cause infection.

Molecular Cellular Microbiology

Author : Philippe Sansonetti
ISBN : 0125215312
Genre : Science
File Size : 81. 70 MB
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This volume in the Methods in Microbiology series focuses on the interaction of microorganisms and the host cell, presenting detailed experimental techniques for modern microbiological research. The book focuses on current technical methods, including imaging technologies, cellular biochemistry, and the establishment and exploitation of cell assay systems. Also covered are methods for studying gene expression and detecting virulence genes. By studying the major techniques used to study cross talk between microbes and cells, rather than just presenting systems, this book distinguishes itself as an essential guide for all researchers working in microbiology, cell biology, and immunology. Key Features * Focuses on current technical methods, including imaging technologies, cellular biochemistry, establishment and exploitation of cell assay systems * Covers promising new areas such as global analysis of genome expression and proteomic analysis of cellular components. * Encompasses the most recent and innovative techniques such as microarrays, new experimental models of infection and new cell assay systems * Provides a large array of models covering the various strategies used by pathogens to infect their host * Includes all current methods developed to study gene expression and detect virulence genes.

Phagocytosis Of Bacteria And Bacterial Pathogenicity

Author : Joel D. Ernst
ISBN : 9781139458054
Genre : Science
File Size : 33. 23 MB
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This book provides up-to-date information on the crucial interaction of pathogenic bacteria and professional phagocytes, the host cells whose purpose is to ingest, kill, and digest bacteria in defense against infection. The introductory chapters focus on the receptors used by professional phagocytes to recognize and phagocytose bacteria, and the signal transduction events that are essential for phagocytosis of bacteria. Subsequent chapters discuss specific bacterial pathogens and the strategies they use in confronting professional phagocytes. Examples include Helicobacter pylori, Streptococcus pneumoniae, and Yersinae, each of which uses distinct mechanisms to avoid being phagocytosed and killed. Contrasting examples include Listeria monocytogenes and Mycobacterium tuberculosis, which survive and replicate intracellularly, and actually cooperate with phagocytes to promote their entry into these cells. Together, the contributions in this book provide an outstanding review of current knowledge regarding the mechanisms of phagocytosis and how specific pathogenic bacteria avoid or exploit these mechanisms.

Lentiviruses And Macrophages

Author : Moira Desport
ISBN : 9781904455608
Genre : Science
File Size : 64. 78 MB
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Lentiviruses comprise a genus of diverse viruses in the Retroviridae family which are united in their ability to infect and persist in macrophages. Infections are characterized by immune system dysfunctions following sometimes lengthy incubation periods. The viruses in this genus include primate lentiviruses, such as HIV, as well as animal lentiviruses, including equine infectious anemia virus (EIAV). An intriguing feature of lentiviruses is their ability to hijack macrophages so that they are simultaneously involved in the dissemination and control of virus spread throughout the host, leading to disease induction and/or transmission to a new host. Macrophage biology is at an exciting stage with a wealth of new information being generated, as their role is dissected in parasitic, viral, and bacterial infections, as well as in chronic inflammatory and autoimmune disease. Despite the devastating infections that lentiviruses cause, they also have enormous potential as research tools due to their ability to integrate into the host genome and are being exploited for use as delivery vehicles in gene therapy. Understanding the lentiviral-macrophage interaction is vital for developing novel antiviral strategies and will permit their use as research tools to be fully realized. Research in this area has never been more exciting! In this timely book, top lentivirus and macrophage specialists comprehensively review cutting-edge topics in the molecular and cellular biology of the lentivirus-macrophage interaction. Topics include: lentivirus tropism and disease, macrophage biology, macrophage in HIV-1 infection and disease progression, post-entry restrictions to lentiviral replication, HIV-2 tropism and disease, SHIV model of disease, the felid immunodeficiency viruses, EIAV, small ruminant lentiviruses, bovine lentiviruses, coinfections, and superinfections. Essential reading for every lentivirologist and retrovirologist, this is also a recommended text for all virology, immunology, and molecular biology laboratories.

Microbial Glycobiology

Author : Anthony P Moran
ISBN : 0080923240
Genre : Science
File Size : 82. 76 MB
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This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of basic and applied research fields, as well as having industrial, medical and biotechnological implications. Individual chapters provided by leading international scientists in the field yield insightful, concise and stimulating reviews Provides researchers with an overview and synthesis of the latest research Each chapter begins with a brief 200 word Summary/Abstract detailing the topic and focus of the chapter, as well as the concepts to be addressed Allows researchers to see at a glance what each chapter will cover Each chapter includes a Research Focus Box Identifies important problems that still need to be solved and areas that require further investigation

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