deep brain stimulation a new frontier in psychiatry

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Deep Brain Stimulation

Author : Damiaan Denys
ISBN : 9783642309908
Genre : Medical
File Size : 70. 35 MB
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This book examines present developments and the future possibilities of deep brain stimulation therapy for patients with therapy-refractory psychiatric disorders. Presents clinical applications and animal research, and offers a chapter on ethical issues.

Brain Stimulation

Author : Andres M. Lozano
ISBN : 9780444534989
Genre : Medical
File Size : 36. 51 MB
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The field of brain stimulation is expanding rapidly, with techniques such as DBS, TMS, and tDCS moving from the research community into clinical diagnosis and treatment. Clinical applications include treating disorders such as Parkinson's disease, dystonia, and even depression. The chapters of Brain Stimulation are written by leading international researchers and clinical specialists include coverage of techniques, modes of action and applications in physiology and therapeutics. The combination of research and clinical coverage will be of interest to neurologists, neurosurgeons, psychiatrists, neuroscientists, and health care workers. A comprehensive introduction and overview of deep brain stimulation (DBS) Coverage of DBS, transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) Details the basic science and research utility of DBS and clinical application


Author : Marc Lévêque
ISBN : 9783319011448
Genre : Medical
File Size : 59. 89 MB
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Psychosurgery, or the surgical treatment of mental disorders, has enjoyed a spectacular revival over the past ten years as new brain stimulation techniques have become available. Neuromodulation offers new possibilities for the treatment of psychiatric disorders such as depression, obsessive-compulsive disorder (OCD), addiction, eating disorders and autism. This work presents the history of this unique specialty and investigates current techniques and ethical challenges. With a wealth of illustrations and detailed anatomical diagrams, it provides essential information for medical practitioners, as well as anyone else interested in the fascinating advances being made in neuroscience today. « I like the book as it provides a very nice overview of psycho- surgery in general. It is easy to understand for any (para)medical practitioner, but even specialists in the field may learn new things. They may also enjoy looking the well-known and less-known figures which illustrate the book. » Professor Bart Nuttin « Reading this book is like reading an anthology, or rather an encyclopaedia of the field of psychiatric surgery, spanning more than a century. This is a work with an unprecedented degree of erudition and knowledge, and the subject is presented in a didactic, scholar, and scientific manner, and is extensively referenced and illustrated. If only one book is to be read by anybody interested in this field, regardless of specialty, this is The Book to read. » Professor Marwan Hariz

Brain Stimulation

Author : Irving Reti
ISBN : 9781118568293
Genre : Medical
File Size : 23. 82 MB
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Brain stimulation technologies are both tools to probe brain function and to provide therapeutic options for patients with neuropsychiatric disease where pharmacological options are not viable. Although the field has been in existence for over seventy years, research interest in brain stimulation has been on the rise particularly in the last two decades. Brain Stimulation: Methodologies and Interventions is an introduction to the field of brain stimulation technology and its applications. The book explores how brain stimulating technologies work in the context of brain pathways that mediate normal and abnormal brain function. Chapters cover neuroanatomy and activitydependent changes in neuronal function triggered by brain stimulation, as well as applications of brain stimulation technologies themselves, including noninvasive procedures that rely on convulsive or seizure therapeutics, and non-convulsive therapies such as magnetic and electrical brain stimulation. Authored by an international group of leaders in the field, Brain Stimulation is a valuable resource for both neuroscience researchers and clinicians. KEY POINTS • Includes introductory chapters on relevant neuroanatomy • Covers both invasive and noninvasive brain stimulation techniques • Explains basic mechanisms and therapeutic applications • Written by an international team of leaders in the field • Illustrated in full color

The Clinical And Ethical Practice Of Neuromodulation Deep Brain Stimulation And Beyond

Author : Markus Christen
ISBN : 9782889453733
Genre :
File Size : 76. 87 MB
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Neuromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.

Emerging Horizons In Neuromodulation

Author :
ISBN : 9780124051805
Genre : Medical
File Size : 31. 78 MB
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This issue of International Review of Neurobiology brings together cutting-edge research on neuromodulation. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery. Brings together cutting-edge research on neuromodulation Reviews current knowledge and understanding Provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery

Non Invasive Brain Stimulation In Neurology And Psychiatry

Author : Ignacio Obeso
ISBN : 9782889451340
Genre :
File Size : 57. 91 MB
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The potential efficacy of non-invasive brain stimulation procedures for the management of specific symptoms in diverse neurological and psychiatric conditions has been tested in the past decade or so. For example, repetitive transcranial magnetic stimulation (rTMS) over prefrontal areas has been extensively investigated as a treatment for patients with medication-resistant depression and has been shown to be associated with improvement of mood. Similarly, non-invasive stimulation techniques have been applied to various symptoms of Parkinson's disease such as bradykinesia and dyskinesias, with variables degrees of success reported. However, attempts to expand previously observed clinical improvements to other neurological disorders (e.g. Tourette's syndrome, autism, epilepsy) has been controversial. In trying to bypass potential confounding elements, researchers aim to target neural populations altered in disease to either increase or decrease their corrupted baseline activity. In addition, a complementary approach is to extend stimulation protocols that results enhanced behavior in healthy participants. This Frontiers Research Topic on non-invasive brain stimulation and enhancement of function tries to combine a series of articles from researchers who used non-invasive brain stimulation to aim improvement of either a motoric, cognitive or behavioral nature investigated behaviorally, physiologically or using brain imaging techniques in clinical populations. Investigation of the relation between enhancement of function in healthy populations and clinical improvement in patients with neurological or psychiatric disorders needs further consideration.

The Development Of Deep Brain Stimulation For Neurological And Psychiatric Disorders Clinical Societal And Ethical Issues

Author : Thomas E. Schlaepfer
ISBN : 9782889190409
Genre :
File Size : 51. 12 MB
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To date more than eighty thousand patients worldwide have received deep brain stimulation (DBS), mainly in order to alleviate symptoms of treatment-resistant disorders such as tremor associated with Parkinson’s disease, essential tremor, chronic pain, epilepsy, obsessive compulsive disorder, major depression and Tourette syndrome. The number of indications for neurological and psychiatric conditions using this technology is rapidly increasing, raising important societal and ethical issues that cannot be dealt with by scientists and clinicians on their own, but need discussions among all possible stakeholders on questions such as: what are the comprehensive risks and benefits of this technology? what is the real impact on patients’ life, in terms of health, quality of life and personal identity? This Research Topic provides an overview of potentials and limitations of deep brain stimulation as used to treat neurological and psychiatric conditions, bringing together Mini Reviews, Perspectives and Opinion papers from key stakeholders interested in the development and social impact of this technology. It is also a continuation of the debate that started among scientists, clinicians, patients, sociologists, journalists, philosophers and other experts during the “brains in dialogue on deep brain stimulation” workshop that was organized in September 2010 in Warsaw, Poland, by the FP7 project bid – brains in dialogue ( coordinated by the Interdisciplinary Laboratory of SISSA (Trieste, Italy).

Deep Brain Stimulation Programming

Author : Erwin B. Montgomery, Jr., MD
ISBN : 9780199890019
Genre : Medical
File Size : 55. 2 MB
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Deep Brain Stimulation (DBS) is a remarkable therapy for an expanding range of neurological and psychiatric disorders. In many cases it is better than best medical therapy and succeeds even when brain transplants fail. Yet despite the remarkable benefits, many physicians and healthcare professionals seem hesitant to embrace this therapy. Post-operative programming of the DBS systems seems unfamiliar, even mysterious, and is viewed as difficult and time consuming. However, DBS programming is rational and can be efficient and effective if one understands the basing underlying concepts of electronics, electrophysiology, and the relevant regional anatomy. Even these principles can be relatively easy to grasp. The book helps the reader to obtain an intuitive understanding of the basic principles of electronics, electrophysiology and the relevant regional anatomy through the use of readily understood metaphors and numerous illustrations. In addition a number of tools are provided including algorithms to ensure efficient and thorough programming. Forms are provided to help with documentation. In addition, DBS related research provides a remarkable tool to understand how the brain works and what happens in diseases such as Parkinson's disease. Already long cherished theories of the pathophysiology of Parkinson's disease must be abandoned. Indeed, these DBS derived insights suggest fundamental revisions of theories of brain function are in order. The book provides an introduction to where some of the new theories may lead particularly with the growing awareness of the importance of oscillations in the brain's activities. The brain has more in common with electrical devices, such as computers, than it does to a stew of chemicals. DBS operates at the electrical level in the brain, which is fundamental to how the brain creates, manipulates and conveys information and may indeed be fundamental to the misinformation the results in the dysfunction related to disorders of the brain. For downloadable forms and other relevant material, please visit:

The New Frontier

Author : Laudan Y. Aron
ISBN : UCSC:32106017736437
Genre : Business & Economics
File Size : 85. 38 MB
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"This report is the first of a multi-year project that focuses on exploring how advancements in neuroscience will impact the abilities of nonprofit human services providers to organize and deliver behavioral health services in the future." Preface.

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