crystallography made crystal clear a guide for users of macromolecular models complementary science

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Crystallography Made Crystal Clear

Author : Gale Rhodes
ISBN : 9780323137782
Genre : Science
File Size : 68. 42 MB
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Crystallography Made Crystal Clear is designed to meet the need for an X-ray analysis that is between brief textbook sections and complete treatments. The book provides non-crystallographers with an intellectually satisfying explanation of the principles of how protein models are gleaned from X-ray analysis. The understanding of these concepts will foster wise use of the models, including the recognition of the strengths and weaknesses of pictures or computer graphics. Since proteins comprise the majority of the mass of macromolecules in cells and carry out biologically important tasks, the book will be of interest to biologists. Provides accessible descriptions of principles of x-ray crystallography, built on simple foundations for anyone with a basic science background Leads the reader through clear, thorough, unintimidating explanations of the mathematics behind crystallography Explains how to read crystallography papers in research journals If you use computer-generated models of proteins or nucleic acids for: Studying molecular interactions Designing ligands, inhibitors, or drugs Engineering new protein functions Interpreting chemical, kinetic, thermodynamic, or spectroscopic data Studying protein folding Teaching macromolecule structure,and if you want to read new structure papers intelligently; become a wiser user of macromolecular models; and want to introduce undergraduates to the important subject of x-ray crystallography, then this book is for you.

Crystallography Made Crystal Clear

Author : Gale Rhodes
ISBN : 0080455549
Genre : Science
File Size : 50. 50 MB
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Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. This is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by a leading expert in the field. Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. Rhodes' personal CMCC Home Page also provides access to tools and links to resources discussed in the text. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers. This updated and expanded new edition uses attractive four-color art, web tool access for further study, and concise language to explain the basis of X-ray crystallography, increasingly vital in today's research labs. * Helps readers to understand where models come from, so they don't use them blindly and inappropriately * Provides many visual and geometric models for understanding a largely mathematical method * Allows readers to judge whether recently published models are of sufficiently high quality and detail to be useful in their own work * Allows readers to study macromolecular structure independently and in an open-ended fashion on their own computers, without being limited to textbook or journals illustrations * Provides access to web tools in a format that will not go out of date. Links will be updated and added as existing resources change location or are added

Crystallography Made Crystal Clear

Author : Gale Rhodes
ISBN : UOM:39015047845154
Genre : Science
File Size : 46. 99 MB
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This edition explains to graduate students and researchers the basics of crystallography for all macromolecules. This updated version contains 35 percent new material, concentrating on the tremendous advances in the desktop programs used for modeling. New topics include neutron and electron diffraction, protein structure determination by NMR, and recent developments in MAD phasing and high speed data collection in crystallography.

Principles Of Protein X Ray Crystallography

Author : Jan Drenth
ISBN : 9781475730920
Genre : Science
File Size : 76. 36 MB
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New textbooks at all levels of chemistry appear with great regularity. Some fields such as basic biochemistry, organic reaction mechanisms, and chemical thermodynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research that is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive intro ductions to their fields. These should serve the needs of one-semester or one-quarter graduate courses in chemistry and biochemistry. In some cases, the availability of texts in active research areas should help stimulate the creation of new courses. Charles R. Cantor v Preface to the Second Edition Since the publication of the previous edition in 1994, X-ray crystallography of proteins has advanced by improvements in existing techniques and by addition of new techniques.

Outline Of Crystallography For Biologists

Author : David Blow
ISBN : 9780198510512
Genre : Medical
File Size : 88. 5 MB
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X-ray crystallography is the main method used to determine the structure of biological molecules. X-ray crystallography is explained without maths and reading this text allows biologists to assess the quality and accuracy of biological structures.

Biophysical Techniques

Author : Iain Campbell
ISBN : 9780199642144
Genre : Medical
File Size : 62. 96 MB
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Biophysical Techniques explains in a readily-accessible way the basics of the various biophysical methods available so students can understand the principles behind the different methods used, and begin to appreciate which tools can be used to probe different biological questions, and the pros and cons of each.

Crystal Structure Determination

Author : Werner Massa
ISBN : 9783662042489
Genre : Science
File Size : 29. 33 MB
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A concise introduction to modern crystal structure determination, emphasizing both the crystallographic background and the successive practical steps. In the theoretical sections, more importance is attached to a good understanding, than to a rigorous mathematical treatment. The most important measuring techniques, including the use of modern area detectors, and the methods of data reduction, structure solution and refinement are discussed from a practical point of view. Special emphasis is put on the ability to recognize and avoid possible errors and traps, and to judge the quality of results.

Physical Biochemistry

Author : David Sheehan
ISBN : 9781118687482
Genre : Science
File Size : 25. 60 MB
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"As will be seen, there is not much missing here. I thought that the sections were well balanced, with rarely too much or too little on a given topic...This is a text to be welcomed by both teachers and students." BIOCHEMISTRY & MOLECULAR BIOLOGY EDUCATION (on the first edition) The second edition of this successful textbook explains the basic principles behind the key techniques currently used in the modern biochemical laboratory and describes the pros and cons of each technique and compares one to another. It is non-mathematical, comprehensive and approachable for students who are not physical chemists. A major update of this comprehensive, accessible introduction to physical biochemistry. Includes two new chapters on proteomics and bioinformatics. Introduces experimental approaches with a minimum of mathematics and numerous practical examples. Provides a bibliography at the end of each chapter. Written by an author with many years teaching and research experience, this text is a must-have for students of biochemistry, biophysics, molecular and life sciences and food science.

Introduction To Protein Structure

Author : Carl-Ivar Brändén
ISBN : 9780815323051
Genre : Medical
File Size : 43. 38 MB
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This new edition gives an up-to-date account of the principles of protein structure, with examples of key proteins in their biological context, illustrated in colour to illuminate the structural principles described in the text.

Protein Crystallography

Author : Eaton E. Lattman
ISBN : 9780801896842
Genre : Science
File Size : 21. 14 MB
Format : PDF
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The crisp writing style and simple illustrations will provide beginner crystallographers with a guide to the process of unraveling protein structure.

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