bioprocess engineering principles second edition

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Bioprocess Engineering Principles

Author : Pauline M. Doran
ISBN : 9780122208515
Genre : Science
File Size : 27. 43 MB
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This welcome new edition covers bioprocess engineering principles for the reader with a limited engineering background. It explains process analysis from an engineering point of view, using worked examples and problems that relate to biological systems. Application of engineering concepts is illustrated in areas of modern biotechnology such as recombinant protein production, bioremediation, biofuels, drug development, and tissue engineering, as well as microbial fermentation. The main sub-disciplines within the engineering curriculum are all covered; Material and Energy Balances, Transport Processes, Reactions and Reactor Engineering. With new and expanded material, Doran's textbook remains the book of choice for students seeking to move into bioprocess engineering. NEW TO THIS EDITION: All chapters thoroughly revised for current developments, with over 200 pgs of new material, including significant new content in: Metabolic Engineering Sustainable Bioprocessing Membrane Filtration Turbulence and Impeller Design Downstream Processing Oxygen Transfer Systems Over 150 new problems and worked examples More than 100 new illustrations New to this edition: All chapters thoroughly revised for current developments, with over 200 pgs of new material, including significant new content in: Metabolic Engineering Sustainable Bioprocessing Membrane Filtration Turbulence and Impeller Design Downstream Processing Oxygen Transfer Systems Over 150 new problems and worked examples More than 100 new illustrations

Bioprocess Engineering

Author : Shijie Liu
ISBN : 9780444637932
Genre : Technology & Engineering
File Size : 30. 39 MB
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Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability. The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems. Includes the mechanistic description of biotransformations and chemical transformations Provides quantitative descriptions of bioprocesses Contains extensive illustrative drawings, which make the understanding of the subject easy Includes bioprocess kinetics and reactor analysis Contains examples of the various process parameters, their significance, and their specific practical use Incorporates sustainability concepts into the various bioprocesses

Solutions Manual

Author : Pauline M. Doran
ISBN : 0733415474
Genre : Biochemical engineering
File Size : 66. 20 MB
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Bioreaction Engineering Principles

Author : Jens Nielsen
ISBN : 9781461507673
Genre : Technology & Engineering
File Size : 21. 1 MB
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This is the second edition of the text "Bioreaction Engineering Principles" by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of "modem" biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of "real" bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter.

Bioprocess Engineering

Author : Michael L. Shuler
ISBN : 9780132901413
Genre : Technology & Engineering
File Size : 81. 85 MB
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The Leading Introduction to Biochemical and Bioprocess Engineering, Updated with Key Advances in Productivity, Innovation, and Safety Bioprocess Engineering, Third Edition, is an extensive update of the world’s leading introductory textbook on biochemical and bioprocess engineering and reflects key advances in productivity, innovation, and safety. The authors review relevant fundamentals of biochemistry, microbiology, and molecular biology, including enzymes, cell functions and growth, major metabolic pathways, alteration of cellular information, and other key topics. They then introduce evolving biological tools for manipulating cell biology more effectively and to reduce costs of bioprocesses. This edition presents major advances in the production of biologicals; highly productive techniques for making heterologous proteins; new commercial applications for both animal and plant cell cultures; key improvements in recombinant DNA microbe engineering; techniques for more consistent authentic post-translational processing of proteins; and other advanced topics. It includes new, improved, or expanded coverage of The role of small RNAs as regulators Transcription, translation, regulation, and differences between prokaryotes and eukaryotes Cell-free processes, metabolic engineering, and protein engineering Biofuels and energy, including coordinated enzyme systems, mixed-inhibition and enzyme-activation kinetics, and two-phase enzymatic reactions Synthetic biology The growing role of genomics and epigenomics Population balances and the Gompetz equation for batch growth and product formation Microreactors for scale-up/scale-down, including rapid scale-up of vaccine production The development of single-use technology in bioprocesses Stem cell technology and utilization Use of microfabrication, nanobiotechnology, and 3D printing techniques Advances in animal and plant cell biotechnology The text makes extensive use of illustrations, examples, and problems, and contains references for further reading as well as a detailed appendix describing traditional bioprocesses. Register your product at informit.com/register for convenient access to downloads, updates, and corrections as they become available.

Fundamentals Of Modern Bioprocessing

Author : Sarfaraz K. Niazi
ISBN : 9781466585744
Genre : Medical
File Size : 57. 52 MB
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Biological drug and vaccine manufacturing has quickly become one of the highest-value fields of bioprocess engineering, and many bioprocess engineers are now finding job opportunities that have traditionally gone to chemical engineers. Fundamentals of Modern Bioprocessing addresses this growing demand. Written by experts well-established in the field, this book connects the principles and applications of bioprocessing engineering to healthcare product manufacturing and expands on areas of opportunity for qualified bioprocess engineers and students. The book is divided into two sections: the first half centers on the engineering fundamentals of bioprocessing; while the second half serves as a handbook offering advice and practical applications. Focused on the fundamental principles at the core of this discipline, this work outlines every facet of design, component selection, and regulatory concerns. It discusses the purpose of bioprocessing (to produce products suitable for human use), describes the manufacturing technologies related to bioprocessing, and explores the rapid expansion of bioprocess engineering applications relevant to health care product manufacturing. It also considers the future of bioprocessing—the use of disposable components (which is the fastest growing area in the field of bioprocessing) to replace traditional stainless steel. In addition, this text: Discusses the many types of genetically modified organisms Outlines laboratory techniques Includes the most recent developments Serves as a reference and contains an extensive bibliography Emphasizes biological manufacturing using recombinant processing, which begins with creating a genetically modified organism using recombinant techniques Fundamentals of Modern Bioprocessing outlines both the principles and applications of bioprocessing engineering related to healthcare product manufacturing. It lays out the basic concepts, definitions, methods and applications of bioprocessing. A single volume comprehensive reference developed to meet the needs of students with a bioprocessing background; it can also be used as a source for professionals in the field.

Principles Of Fermentation Technology

Author : Peter F Stanbury
ISBN : 9780444634085
Genre : Technology & Engineering
File Size : 79. 71 MB
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The successful structure of the previous edition of Principles of Fermentation Technology has been retained in this third edition, which covers the key component parts of a fermentation process including growth kinetics, strain isolation and improvement, inocula development, fermentation media, fermenter design and operation, product recovery, and the environmental impact of processes. This accurate and accessible third edition recognizes the increased importance of animal cell culture, the impact of the post-genomics era on applied science and the huge contribution that heterologous protein production now makes to the success of the pharmaceutical industry. This title is ideally suited for both newcomers to the industry and established workers as it provides essential and fundamental information on fermentation in a methodical, logical fashion. Stanbury, Whitaker and Hall have integrated the biological and engineering aspects of fermentation to make the content accessible to members of both disciplines with a focus on the practical application of theory. This text collates all the fermentation fundamentals into one concise reference, making it a valuable resource for fermentation scientists, as well as those studying in the field. Retains its successful structure and covers all components of the fermentation process Integrates the biological and engineering aspects of fermentation to discuss the most recent developments and advancements in the field Written in a style accessible to readers from either a biological or engineering background with each chapter supported by an extensive bibliography

Metabolic Engineering

Author : Jens Nielsen
ISBN : 9783540453000
Genre : Science
File Size : 30. 17 MB
Format : PDF
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Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae for xylose metabolism, and the improvement of a complex biotransformation process.

Principles Of Bioseparations Engineering

Author : Raja Ghosh
ISBN : 9789813106765
Genre : Technology & Engineering
File Size : 51. 92 MB
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Bioseparations engineering deals with the scientific and engineering principles involved in large-scale separation and purification of biological products. It is a key component of most chemical engineering/biotechnology/bioprocess engineering programmes. This book discusses the underlying principles of bioseparations engineering written from the perspective of an undergraduate course. It covers membrane based bioseparations in much more detail than some of the other books on bioseparations engineering. Based largely on the lecture notes the author developed to teach the course, this book is especially suitable for use as an undergraduate level textbook, as most other textbooks are targeted at graduate students.

Fermentation And Biochemical Engineering Handbook

Author : Celeste M. Todaro
ISBN : 9781455730469
Genre : Technology & Engineering
File Size : 67. 59 MB
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A complete reference for fermentation engineers engaged in commercial chemical and pharmaceutical production, Fermentation and Biochemical Engineering Handbook emphasizes the operation, development and design of manufacturing processes that use fermentation, separation and purification techniques. Contributing authors from companies such as Merck, Eli Lilly, Amgen and Bristol-Myers Squibb highlight the practical aspects of the processes—data collection, scale-up parameters, equipment selection, troubleshooting, and more. They also provide relevant perspectives for the different industry sectors utilizing fermentation techniques, including chemical, pharmaceutical, food, and biofuels. New material in the third edition covers topics relevant to modern recombinant cell fermentation, mammalian cell culture, and biorefinery, ensuring that the book will remain applicable around the globe. It uniquely demonstrates the relationships between the synthetic processes for small molecules such as active ingredients, drugs and chemicals, and the biotechnology of protein, vaccine, hormone, and antibiotic production. This major revision also includes new material on membrane pervaporation technologies for biofuels and nanofiltration, and recent developments in instrumentation such as optical-based dissolved oxygen probes, capacitance-based culture viability probes, and in situ real-time fermentation monitoring with wireless technology. It addresses topical environmental considerations, including the use of new (bio)technologies to treat and utilize waste streams and produce renewable energy from wastewaters. Options for bioremediation are also explained. Fully updated to cover the latest advances in recombinant cell fermentation, mammalian cell culture and biorefinery, along with developments in instrumentation Industrial contributors from leading global companies, including Merck, Eli Lilly, Amgen, and Bristol-Myers Squibb Covers synthetic processes for both small and large molecules

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