biomedical applications and toxicology of carbon nanomaterials

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Biomedical Applications And Toxicology Of Carbon Nanomaterials

Author : Chunying Chen
ISBN : 9783527338719
Genre : Medical
File Size : 71. 35 MB
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An overview of biomedical applications and the toxicity properties of carbon nanomaterials aimed at helping to avoid detrimental health effects while laying the groundwork for further research in this highly relevant field. Summarizing recent research, the book starts with the synthesis and functionalization of carbon nanomaterials, as well as identification and detection in biosystems. It then moves on to the interaction between carbon nanoparticles and biocomponents, focusing on the toxicity and mechanisms to various organs and systems and potential biomedical applications as well. Each section highlights the challenges, outlines unanswered questions, and suggests directions for further research and development efforts.

Carbon Nanotubes For Biomedical Applications

Author : Rüdiger Klingeler
ISBN : 3642148026
Genre : Technology & Engineering
File Size : 61. 59 MB
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This book explores the potential of multi-functional carbon nanotubes for biomedical applications. It combines contributions from chemistry, physics, biology, engineering, and medicine. The complete overview of the state-of-the-art addresses different synthesis and biofunctionalisation routes and shows the structural and magnetic properties of nanotubes relevant to biomedical applications. Particular emphasis is put on the interaction of carbon nanotubes with biological environments, i.e. toxicity, biocompatibility, cellular uptake, intracellular distribution, interaction with the immune system and environmental impact. The insertion of NMR-active substances allows diagnostic usage as markers and sensors, e.g. for imaging and contactless local temperature sensing. The potential of nanotubes for therapeutic applications is highlighted by studies on chemotherapeutic drug filling and release, targeting and magnetic hyperthermia studies for anti-cancer treatment at the cellular level.

Carbon Nanomaterials For Biomedical Applications

Author : Mei Zhang
ISBN : 9783319228617
Genre : Technology & Engineering
File Size : 64. 86 MB
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This book covers a wide range of topics relating to carbon nanomaterials, from synthesis and functionalization to applications in advanced biomedical devices and systems. As they possess unique and attractive chemical, physical, optical, and even magnetic properties for various applications, considerable effort has been made to employ carbon nanomaterials (e.g., fullerenes, carbon nanotubes, graphene, nanodiamond) as new materials for the development of novel biomedical tools, such as diagnostic sensors, imaging agents, and drug/gene delivery systems for both diagnostics and clinical treatment. Tremendous progress has been made and the scattered literature continues to grow rapidly. With chapters by world-renowned experts providing an overview of the state of the science as well as an understanding of the challenges that lie ahead, Carbon Nanomaterials for Biomedical Applications is essential reading not only for experienced scientists and engineers in biomedical and nanomaterials areas, but also for graduate students and advanced undergraduates in materials science and engineering, chemistry, and biology.

Nanomaterials For Medical Applications

Author : Zoraida Aguilar
ISBN : 9780123850898
Genre : Medical
File Size : 90. 65 MB
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This title covers recent advances in a variety of biomedical applications of nanostructured materials, as the field evolves from prototype device to real-world application. It presents the main types of nanomaterial used in medical application today: semiconductor nanomaterials, Magnetic nanomaterials, metal nanoparticles, Carbon nanomaterials, Hydrogel nanocomposites, Liposomes, Dendrimers, Polymer nanocomposites, and Biodegradable polymers. Structurally the work is demarcated into the six most popular areas of research: (1) biocompatibility of nanomaterials with living organisms in their various manifestations (2) nanobiosensors for clinical diagnostics, detecting biomolecules which are useful in the clinical diagnosis of genetic, metabolically acquired, induced or infectious disease (3) targeted drug delivery for nanomaterials in their various modifications (4) nanomedical devices and structures which are used in the development of implantable medical devices and structures such as nanorobots (5) nanopharmacology, as novel nanoparticles are increasingly engineered to diagnose conditions and recognize pathogens, identify ideal pharmaceutical agents to treat the condition or pathogens,fuel high-yield production of matched pharmaceuticals (potentially in vivo), locate, attach or enter target tissue, structures or pathogens; and dispense the ideal mass of matched biological compound to the target regions (6) nanotoxicology and remediation, which focuses on finished and on-going various toxicity evaluations on various nanomaterials that are used and currently being developed for medical applications Discusses the most important biomedical applications and devices of nanomaterials: drug delivery, medical imaging, gene therapy, nanorobots, biosensors and diagnostics Focuses on current commercialized techniques and applications, ensuring the work is entirely relevant to a rapidly evolving field Reviews the most recent studies on nanomaterial toxicity, thereby responding to the widescale private, policy and public interest in nanoscience

Carbon Nanomaterials For Biological And Medical Applications

Author : Sekhar Chandra Ray
ISBN : 9780323479073
Genre : Technology & Engineering
File Size : 20. 19 MB
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Nanomaterials for Biological and Medical Applications explores the different applications of carbon nanomaterials in drug and gene therapies and their use in tissue regeneration, biosensor diagnosis, enantiomer separation of chiral drugs, extraction and analysis of drugs and pollutants, and as antitoxents. The book describes the synthesis processing of carbon nanomaterials, carbon composite nanomaterials, and their different biological and biomedical applications, including the removal of biologically toxic materials, optical biosensor applications, bio-imaging probe, drug delivery, cancer treatments, and other biomedical applications. Explains the major synthesis chemical process of carbon nanomaterials for biological applications Discusses how carbon nanomaterials can be practically used to create more efficient nanodevices in biosensing, medical imaging, and drug delivery Explores how the unique physical properties of carbon nanomaterials allows them to remove biologically toxic materials

Biomedical Applications Of Carbon Nanotubes

Author : Zhuang Liu
ISBN : STANFORD:36105210237991
Genre :
File Size : 77. 34 MB
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The Toxicology Of Carbon Nanotubes

Author : Ken Donaldson
ISBN : 9781139510530
Genre : Science
File Size : 24. 86 MB
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The widespread and increasing use of carbon nanotubes in scientific and engineering research and their incorporation into manufactured goods has urged an assessment of the risks and hazards associated with exposure to them. The field of nanotoxicology studies the toxicology of nanoparticles such as carbon nanotubes and has become a major growth area aimed towards risk assessment of nanoparticles. Compiled by a team of leading experts at the forefront of research, this is the first book dedicated to the toxicology of carbon nanotubes. It provides state-of-the-science information on how and why they are so potentially dangerous if breathed in, including their similarities to asbestos. The book examines various aspects of carbon nanotubes, from their manufacture and aerodynamic behaviour to their effects at molecular level in the lungs. It is invaluable to the many groups involved with research in this area, as well as to regulators and risk assessors.

Medicinal Chemistry And Pharmacological Potential Of Fullerenes And Carbon Nanotubes

Author : Franco Cataldo
ISBN : 9781402068454
Genre : Science
File Size : 26. 19 MB
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Fullerenes and nanotubes are two classes of carbon structures or allotropes, which were discovered about 17 years ago. Since that time, many chemical derivatives have been synthesized using fullerenes and nanotubes as building blocks. Particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances. In addition, the funtionalization of nanotubes has not only produced relatively simple derivatives, but also complex hybrids with biological macromolecules, which show unique supramolecular architecture and which are promising in many medical applications. The application of fullerenes and nanotubes in medicine is at the frontier of our knowledge, thus the work in this field represents the basis for future novel developments.

Safety Of Nanoparticles

Author : Thomas J. Webster
ISBN : 0387786082
Genre : Technology & Engineering
File Size : 50. 24 MB
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In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials. There are numerous and well-known risks because of the size of nanoparticles. For example, nanoparticles can cross cell membranes and enter the cytoplasm undetected. The aim of this book is to provide one of the first (if not the first) detailed views of how cells and tissues in the body deal with nanoparticles. This is important not only for implantable devices, but also for the manufacturing of nanophase materials when particles can be inhaled or enter the body through the skin. Only by compiling research at the intersection of nanoparticles and biological processes can we determine if nanophase materials are safe to be manufactured, handled, and/or implanted for various medical applications.

Carbon Nanotubes

Author : Silvana Fiorito
ISBN : 9789814241014
Genre : Medical
File Size : 53. 5 MB
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Fiorito presents an overall view of carbon nanotubes (CNTs), describing both the positive and negative aspects of this material. She explains the physicochemical properties of CNTs, discusses their applications in mechanics and sensors, and biology and medicine, and describes the possible toxic effects associated with their use.

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