biochemistry of signal transduction and regulation lecture notes series

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Biochemistry Of Signal Transduction And Regulation

Author : Gerhard Krauss
ISBN : 9783527667499
Genre : Science
File Size : 26. 84 MB
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Originally based on a graduate course taught by the author, this true classic has once again been extensively updated to incorporate key new findings in biological signaling. With over half of the content re-written, plus 70 brand new and 50 revised figures, this is the most up-to-date textbook on signaling available anywhere. Thanks to its clear structure, hundreds of illustrative drawings, as well as chapter introductions and newly added study questions, this text excels as a companion for a course on biological signaling, and equally as an introductory reference to the field for students and researchers. Generations of students and junior researchers have relied on "the Krauss" to find their way through the bewildering complexity of biological signaling pathways.

Signal Transduction

Author : Bastien D. Gomperts
ISBN : 0122896327
Genre : Medical
File Size : 40. 11 MB
Format : PDF, Kindle
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Signal Transduction now in paperback, is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix, etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particulary cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources key observations and experiments that set the scence for recent and current work. * Coherent, precise text providing insight in depth to a subject that is central to cell biology and fundamental to many areas of biomedicine * Conceptual colour artwork assists with the comprehension of key topics * Extensive referencing provides an invaluable link to the core and historical literature * Margin notes highlighting milestones in the evolution of our understanding of signalling mechanisms

Cellular Signal Processing

Author : Friedrich Marks
ISBN : 9781351677219
Genre : Medical
File Size : 90. 2 MB
Format : PDF
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Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.

Lehninger Principles Of Biochemistry

Author : David L. Nelson
ISBN : 9780716771081
Genre : Science
File Size : 75. 29 MB
Format : PDF
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Authors Dave Nelson and Mike Cox combine the best of the laboratory and best of the classroom, introducing exciting new developments while communicating basic principles of biochemistry.

Molecular Biology Of The Cell

Author : Bruce Alberts
ISBN : 9781317563747
Genre : Science
File Size : 69. 49 MB
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As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.

Cell Signaling

Author : Wendell Lim
ISBN : 9781317573623
Genre : Science
File Size : 40. 25 MB
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Cell Signaling presents the principles and components that underlie all known signaling processes. It provides undergraduate and graduate students the conceptual tools needed to make sense of the dizzying array of pathways used by the cell to communicate. By emphasizing the common design principles, components, and logic that drives all signaling, the book develops a conceptual framework through which students can understand how thousands of diverse signaling proteins interact with each other in vast interconnected networks. The book first examines the common currencies of cellular information processing and the core components of the signaling machinery. It then shows how these individual components link together into networks and pathways to perform more sophisticated tasks. Many specific examples are provided throughout to illustrate common principles, and provide a comprehensive overview of major eukaryotic signaling pathways.

Usmle Step 1 Lecture Notes 2017 Biochemistry And Medical Genetics

Author : Kaplan
ISBN : 9781506208350
Genre : Medical
File Size : 48. 86 MB
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The only official Kaplan Lecture Notes for USMLE Step 1 cover the comprehensive information you need to ace the exam and match into the residency of your choice. * Up-to-date: Updated annually by Kaplan’s all-star faculty * Integrated: Packed with clinical correlations and bridges between disciplines * Learner-efficient: Organized in outline format with high-yield summary boxes * Trusted: Used by thousands of students each year to succeed on USMLE Step 1

Usmle Step 1 Lecture Notes 2017 Biochemistry And Medical Genetics

Author : Kaplan Medical
ISBN : 9781506209494
Genre : Medical
File Size : 56. 18 MB
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The only official Kaplan Lecture Notes for USMLE Step 1 cover the comprehensive information you need to ace the exam and match into the residency of your choice. * Up-to-date: Updated annually by Kaplan’s all-star faculty * Integrated: Packed with clinical correlations and bridges between disciplines * Learner-efficient: Organized in outline format with high-yield summary boxes * Trusted: Used by thousands of students each year to succeed on USMLE Step 1

Usmle Step 1 Lecture Notes 2018 Biochemistry And Medical Genetics

Author : Kaplan Medical
ISBN : 9781506221083
Genre : Medical
File Size : 73. 62 MB
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Kaplan Medical's USMLE Step 1 Lecture Notes 2018: Biochemistry and Medical Genetics offers in-depth review with a focus on high-yield topics – a comprehensive approach that will help you deepen your understanding while focusing your efforts where they'll count the most. Used by thousands of medical students each year to succeed on USMLE Step 1, Kaplan's official lecture notes are packed with full-color diagrams and clear review. The Best Review Organized in outline format with high-yield summary boxes for efficient study. Clinical correlations and bridges between disciplines highlighted throughout. Full-color diagrams and charts for better comprehension and retention. Updated annually by Kaplan's all-star expert faculty Looking for more prep? Our USMLE Step 1 Lecture Notes 2018: 7-Book Set has this book, plus the rest of the 7-book series.

Signal Transduction

Author : Ijsbrand M. Kramer
ISBN : 9780123948199
Genre : Science
File Size : 77. 94 MB
Format : PDF
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A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor – ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition. In-depth insight into a subject central to cell biology and fundamental to biomedicine, including the search for novel therapeutic interventions Essential signaling events embedded in rich physiological and pathological contexts Extensive conceptual colour artwork to assist with comprehension of key topics Special emphasis on how molecular structure determines protein function and subcellular localization Employment of unambiguous protein names (symbols) in agreement with leading protein- and gene databases, allowing the learner to extend his/her exploration on the web

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