biochemistry of signal transduction and regulation lecture notes series

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Plant Biochemistry

Author : Florence Gleason
ISBN : 9780763764012
Genre : Science
File Size : 90. 51 MB
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Written for the upper-level undergraduate and graduate course, Plant Biochemistry provides a comprehensive, student-friendly introduction to this interesting area of study. It opens with a review of basic concepts in cell and molecular biology as well as basic chemistry, and moves on to discuss the analysis of photosynthesis and carbon metabolism in plants. An introduction to carbohydrates is followed by a discussion of primary cell wall structure and synthesis. To ensure full student comprehension and retention it takes care to introduce basic metabolic pathways for synthesis of lipids, steroids, and aromatic amino acids before discussing natural products such as lignin, flavonoids, and alkaloids. Student and instructor materials are available to enhance the course.

Lehrbuch Der Biochemie

Author : Donald Voet
ISBN : 3527326677
Genre : Biochemistry
File Size : 69. 91 MB
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Ein echter Voet: Leicht verständliche chemische Grundlagen, brillante Strukturbilder und eine durchgehende Erklärung biochemischer Phänomene aus den zu Grunde liegenden molekularen Mechanismen - das sind die Markenzeichen des "Voet". Wer mit diesem Buch lernt, erfährt nicht nur das "Was?", sondern immer auch das "Warum?". Zahlreiche Exkurse in die Molekularbiologie, die Biomedizin und in andere verwandte Wissenschaften stellen fachübergreifende Bezüge her und führen gleichzeitig in aktuelle Fragestellungen aus der biochemischen Forschung ein. Neu in der zweiten Auflage: Ein zusätzliches Kapitel über biologische Signaltransduktion. Hier werden die wichtigsten Signalwege besprochen: Hormonelle Steuerung, Tyrosinkinasen, G-Proteine, und der Phosphoinositolweg. Über 100 neue hochaufgelöste Protein- und Nucleinsäurestrukturen samt den daraus abgeleiteten Erkenntnissen zu molekularen Mechanismen. Viele neue Molekularstrukturen, u. a. Chaperoninkomplexe, SNARE-Komplex, spannungsabhängige Ionenkanäle, ABC-Transporter, G-Proteine, Cytochrom c-Oxidase, ATP Synthase, Pyruvatdehydrogenasekomplex, RNA Polymerase II, RNAse P, kleine und große ribosomale Untereinheit. Neue Exkurse stellen 21 berühmte Biochemiker und ihre bahnbrechenden Entdeckungen vor, darunter Linus Pauling, Otto Warburg, Hans Krebs, Max Perutz, Arthur Kornberg. Aktuelle Forschungsschwerpunkte mit direktem Bezug zur Biochemie werden vorgestellt; u. a. Genomsequenzierung, Systembiologie, Metabolomik, Proteindatenbanken, Epigenetik, Biofi lme, Prionenkrankheiten, RNA-Interferenz, pharmazeutische Wirkstoffentwicklung, Vesikeltransport, Apoptose, "Riboswitches". 450 Übungsaufgaben mit Lösungen im Anhang stehen zur Lernkontrolle zur Verfügung, darunter mehr als 150 neue. Die Multimedia-Unterstützung ist jetzt mit rund 250 Animationen und interaktiven Übungen noch umfangreicher und über das Internet jederzeit frei zugänglich. Stimmen zur ersten Auflage: "Der Titel der Originalausgabe ... Fundamentals of Biochemistry ist verräterisch. Es ist ein Grundlagenlehrbuch, das sich primär an Studenten aller Fachrichtungen richtet, die einführende Vorlesungen der Biochemie hören. Das Schwergewicht liegt hier weniger auf enzyklopädischer Detailfülle als auf Prinzipien und deren Verständnis. Der Voet/Voet/Pratt ist "Didaktik pur"! Chemie in unserer Zeit "Das Buch ist sehr ausführlich, aber trotzdem gut strukturiert geschrieben... Zudem fließen oft aktuelle Forschungsbereiche ein, so dass es sehr angenehm ist mit dem Lehrbuch der Biochemie zu arbeiten und zu lernen." uni-online

Introduction To Bioorganic Chemistry And Chemical Biology

Author : David Van Vranken
ISBN : 9781135054823
Genre : Medical
File Size : 49. 23 MB
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Introduction to Bioorganic Chemistry and Chemical Biology is the first textbook to blend modern tools of organic chemistry with concepts of biology, physiology, and medicine. With a focus on human cell biology and a problems-driven approach, the text explains the combinatorial architecture of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engine for life. Accentuated by rich illustrations and mechanistic arrow pushing, organic chemistry is used to illuminate the central dogma of molecular biology. Introduction to Bioorganic Chemistry and Chemical Biology is appropriate for advanced undergraduate and graduate students in chemistry and molecular biology, as well as those going into medicine and pharmaceutical science.

Formal Methods Foundations And Applications

Author : Christiano Braga
ISBN : 9783319150758
Genre : Computers
File Size : 85. 15 MB
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This book constitutes the thoroughly refereed post-conference proceedings of the 17th Brazilian Symposium on Formal Methods, SBMF 2014, held in Maceió, Brazil, in September/October 2014. The 9 revised full papers presented together with 2 invited talks were carefully reviewed and selected from 34 submissions. SBMF is an event devoted to the dissemination of the development and use of formal methods for the construction of high quality computational systems, aiming to promote opportunities for researchers with interests in formal methods to discuss the recent advances in this area.

Biomolecular Networks

Author : Luonan Chen
ISBN : 0470488050
Genre : Computers
File Size : 23. 39 MB
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Alternative techniques and tools for analyzing biomolecular networks With the recent rapid advances in molecular biology, high-throughput experimental methods have resulted in enormous amounts of data that can be used to study biomolecular networks in living organisms. With this development has come recognition of the fact that a complicated living organism cannot be fully understood by merely analyzing individual components. Rather, it is the interactions of components or biomolecular networks that are ultimately responsible for an organism's form and function. This book addresses the important need for a new set of computational tools to reveal essential biological mechanisms from a systems biology approach. Readers will get comprehensive coverage of analyzing biomolecular networks in cellular systems based on available experimental data with an emphasis on the aspects of network, system, integration, and engineering. Each topic is treated in depth with specific biological problems and novel computational methods: GENE NETWORKS—Transcriptional regulation; reconstruction of gene regulatory networks; and inference of transcriptional regulatory networks PROTEIN INTERACTION NETWORKS—Prediction of protein-protein interactions; topological structure of biomolecular networks; alignment of biomolecular networks; and network-based prediction of protein function METABOLIC NETWORKS AND SIGNALING NETWORKS—Analysis, reconstruction, and applications of metabolic networks; modeling and inference of signaling networks; and other topics and new trends In addition to theoretical results and methods, many computational software tools are referenced and available from the authors' Web sites. Biomolecular Networks is an indispensable reference for researchers and graduate students in bioinformatics, computational biology, systems biology, computer science, and applied mathematics.

The Immune System And Mental Health

Author : Hymie Anisman
ISBN : 9780128113523
Genre : Medical
File Size : 58. 2 MB
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The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. Sociology, psychology, psychiatry, neuroscience and genetics have provided considerable explanations and solutions to some of the most intractable mental-health problems. But researchers are increasingly relying on investigations of the immune system to identify factors that can undermine and impair mental health. This book covers devastating mental-health conditions, such as depression, anxiety, schizophrenia, and autism-like spectrum disorders. In addition, degenerative disorders of the brain, such as Parkinson’s and Alzheimer’s-like dementia are explored. Considers both basic human and animal studies that address immunological changes relating to mental health problems across the lifespan Incorporates techniques, concepts and ideas from a variety of social, behavioral and life sciences Explores the relatively new area of the microbiome and how the microbial composition of the gut influences brain function and mental health

American Book Publishing Record

Author :
ISBN : UOM:39015066180459
Genre : American literature
File Size : 90. 16 MB
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Molekulare Biotechnologie

Author : David Clark
ISBN : 9783827421890
Genre : Science
File Size : 51. 43 MB
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Grundlage aller biotechnologischen Prozesse sind molekularbiologische und genetische Regelmechanismen. Deshalb behandelt dieses neuartige Lehrbuch beides: die molekularbiologischen Grundlagen und die Anwendungen. Spannend und aktuell werden die Teilgebiete der Biotechnologie und das jeweils erforderliche molekularbiologische Grundwissen beschrieben. Der Bogen wird gespannt von der Nanobiotechnologie über Stoffwechseltechnologie, Genomics und Umweltbiotechnologie bis hin zur Gentherapie.

Research Centers Directory

Author :
ISBN : 0810383578
Genre : Learned institutions and societies
File Size : 87. 84 MB
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Research institutes, foundations, centers, bureaus, laboratories, experiment stations, and other similar nonprofit facilities, organizations, and activities in the United States and Canada. Entry gives identifying and descriptive information of staff and work. Institutional, research centers, and subject indexes. 5th ed., 5491 entries; 6th ed., 6268 entries.

Molekulare Zellbiologie

Author : Arnold Berk
ISBN : 9783110810578
Genre : Science
File Size : 82. 27 MB
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