applied missing data analysis in the health sciences statistics in practice

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Applied Missing Data Analysis In The Health Sciences

Author : Xiao-Hua Zhou
ISBN : 9781118573648
Genre : Medical
File Size : 28. 12 MB
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A modern and practical guide to the essential concepts and ideas for analyzing data with missing observations in the field of biostatistics With an emphasis on hands-on applications, Applied Missing Data Analysis in the Health Sciences outlines the various modern statistical methods for the analysis of missing data. The authors acknowledge the limitations of established techniques and provide newly-developed methods with concrete applications in areas such as causal inference methods and the field of diagnostic medicine. Organized by types of data, chapter coverage begins with an overall introduction to the existence and limitations of missing data and continues into traditional techniques for missing data inference, including likelihood-based, weighted GEE, multiple imputation, and Bayesian methods. The book’s subsequently covers cross-sectional, longitudinal, hierarchical, survival data. In addition, Applied Missing Data Analysis in the Health Sciences features: Multiple data sets that can be replicated using the SAS®, Stata®, R, and WinBUGS software packages Numerous examples of case studies in the field of biostatistics to illustrate real-world scenarios and demonstrate applications of discussed methodologies Detailed appendices to guide readers through the use of the presented data in various software environments Applied Missing Data Analysis in the Health Sciences is an excellent textbook for upper-undergraduate and graduate-level biostatistics courses as well as an ideal resource for health science researchers and applied statisticians.

Applied Mixed Models In Medicine

Author : Helen Brown
ISBN : 9781118778258
Genre : Medical
File Size : 55. 76 MB
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Network Meta Analysis For Decision Making

Author : Sofia Dias
ISBN : 9781118647509
Genre : Mathematics
File Size : 41. 6 MB
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A practical guide to network meta-analysis with examples and code In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question “for this pre-identified population of patients, which treatment is ‘best’?” A comprehensive, coherent framework for network meta-analysis (mixed treatment comparisons) is adopted and estimated using Bayesian Markov Chain Monte Carlo methods implemented in the freely available software WinBUGS. Each chapter contains worked examples, exercises, solutions and code that may be adapted by readers to apply to their own analyses. This book can be used as an introduction to evidence synthesis and network meta-analysis, its key properties and policy implications. Examples and advanced methods are also presented for the more experienced reader. Methods used throughout this book can be applied consistently: model critique and checking for evidence consistency are emphasised. Methods are based on technical support documents produced for NICE Decision Support Unit, which support the NICE Methods of Technology Appraisal. Code presented is also the basis for the code used by the ISPOR Task Force on Indirect Comparisons. Includes extensive carefully worked examples, with thorough explanations of how to set out data for use in WinBUGS and how to interpret the output. Network Meta-Analysis for Decision Making will be of interest to decision makers, medical statisticians, health economists, and anyone involved in Health Technology Assessment including the pharmaceutical industry.

Missing Data Analysis In Practice

Author : Trivellore Raghunathan
ISBN : 9781482211931
Genre : Mathematics
File Size : 54. 84 MB
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Missing Data Analysis in Practice provides practical methods for analyzing missing data along with the heuristic reasoning for understanding the theoretical underpinnings. Drawing on his 25 years of experience researching, teaching, and consulting in quantitative areas, the author presents both frequentist and Bayesian perspectives. He describes easy-to-implement approaches, the underlying assumptions, and practical means for assessing these assumptions. Actual and simulated data sets illustrate important concepts, with the data sets and codes available online. The book underscores the development of missing data methods and their adaptation to practical problems. It mainly focuses on the traditional missing data problem. The author also shows how to use the missing data framework in many other statistical problems, such as measurement error, finite population inference, disclosure limitation, combing information from multiple data sources, and causal inference.

Methods And Applications Of Statistics In The Life And Health Sciences

Author : N. Balakrishnan
ISBN : 9780470405093
Genre : Mathematics
File Size : 33. 16 MB
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"Data collection holds an essential part in dictating the future of health sciences and public health, as the compilation of statistics allows researchers and medical practitioners to monitor trends in health status, identify health problems, and evaluate the impact of health policies and programs. Methods and Applications of Statistics in the Life and Health Sciences serves as a single, one-of-a-kind resource on the wide range of statistical methods, techniques, and applications that are applied in modern life and health sciences in research. Specially designed to present encyclopedic content in an accessible and self-contained format, this book outlines thorough coverage of the underlying theory and standard applications to research in related disciplines such as biology, epidemiology, clinical trials, and public health. Uniquely combining established literature with cutting-edge research, this book contains classical works and more than twenty-five new articles and completely revised contributions from the acclaimed Encyclopedia of Statistical Sciences, Second Edition. The result is a compilation of more than eighty articles that explores classic methodology and new topics."--Publisher's description.

Applied Linear Regression

Author : Sanford Weisberg
ISBN : 9781118594858
Genre : Mathematics
File Size : 62. 20 MB
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Praise for the Third Edition "...this is an excellent book which could easily be used as a course text..." —International Statistical Institute The Fourth Edition of Applied Linear Regression provides a thorough update of the basic theory and methodology of linear regression modeling. Demonstrating the practical applications of linear regression analysis techniques, the Fourth Edition uses interesting, real-world exercises and examples. Stressing central concepts such as model building, understanding parameters, assessing fit and reliability, and drawing conclusions, the new edition illustrates how to develop estimation, confidence, and testing procedures primarily through the use of least squares regression. While maintaining the accessible appeal of each previous edition,Applied Linear Regression, Fourth Edition features: Graphical methods stressed in the initial exploratory phase, analysis phase, and summarization phase of an analysis In-depth coverage of parameter estimates in both simple and complex models, transformations, and regression diagnostics Newly added material on topics including testing, ANOVA, and variance assumptions Updated methodology, such as bootstrapping, cross-validation binomial and Poisson regression, and modern model selection methods Applied Linear Regression, Fourth Edition is an excellent textbook for upper-undergraduate and graduate-level students, as well as an appropriate reference guide for practitioners and applied statisticians in engineering, business administration, economics, and the social sciences.

Longitudinal Data Analysis

Author : Donald Hedeker
ISBN : 9780470036471
Genre : Mathematics
File Size : 36. 56 MB
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Longitudinal data analysis for biomedical and behavioral sciences This innovative book sets forth and describes methods for the analysis of longitudinaldata, emphasizing applications to problems in the biomedical and behavioral sciences. Reflecting the growing importance and use of longitudinal data across many areas of research, the text is designed to help users of statistics better analyze and understand this type of data. Much of the material from the book grew out of a course taught by Dr. Hedeker on longitudinal data analysis. The material is, therefore, thoroughly classroom tested and includes a number of features designed to help readers better understand and apply the material. Statistical procedures featured within the text include: * Repeated measures analysis of variance * Multivariate analysis of variance for repeated measures * Random-effects regression models (RRM) * Covariance-pattern models * Generalized-estimating equations (GEE) models * Generalizations of RRM and GEE for categorical outcomes Practical in their approach, the authors emphasize the applications of the methods, using real-world examples for illustration. Some syntax examples are provided, although the authors do not generally focus on software in this book. Several datasets and computer syntax examples are posted on this title's companion Web site. The authors intend to keep the syntax examples current as new versions of the software programs emerge. This text is designed for both undergraduate and graduate courses in longitudinal data analysis. Instructors can take advantage of overheads and additional course materials available online for adopters. Applied statisticians in biomedicine and the social sciences can also use the book as a convenient reference.

Multivariate Statistics

Author : Yasunori Fujikoshi
ISBN : 9780470411698
Genre : Mathematics
File Size : 54. 58 MB
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A comprehensive examination of high-dimensional analysis ofmultivariate methods and their real-world applications Multivariate Statistics: High-Dimensional and Large-SampleApproximations is the first book of its kind to explore howclassical multivariate methods can be revised and used in place ofconventional statistical tools. Written by prominent researchers inthe field, the book focuses on high-dimensional and large-scaleapproximations and details the many basic multivariate methods usedto achieve high levels of accuracy. The authors begin with a fundamental presentation of the basictools and exact distributional results of multivariate statistics,and, in addition, the derivations of most distributional resultsare provided. Statistical methods for high-dimensional data, suchas curve data, spectra, images, and DNA microarrays, are discussed.Bootstrap approximations from a methodological point of view,theoretical accuracies in MANOVA tests, and model selectioncriteria are also presented. Subsequent chapters feature additionaltopical coverage including: High-dimensional approximations of various statistics High-dimensional statistical methods Approximations with computable error bound Selection of variables based on model selection approach Statistics with error bounds and their appearance indiscriminant analysis, growth curve models, generalized linearmodels, profile analysis, and multiple comparison Each chapter provides real-world applications and thoroughanalyses of the real data. In addition, approximation formulasfound throughout the book are a useful tool for both practical andtheoretical statisticians, and basic results on exact distributionsin multivariate analysis are included in a comprehensive, yetaccessible, format. Multivariate Statistics is an excellent book for courseson probability theory in statistics at the graduate level. It isalso an essential reference for both practical and theoreticalstatisticians who are interested in multivariate analysis and whowould benefit from learning the applications of analyticalprobabilistic methods in statistics.

Modes Of Parametric Statistical Inference

Author : Seymour Geisser
ISBN : 9780471743125
Genre : Mathematics
File Size : 32. 47 MB
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A fascinating investigation into the foundations of statistical inference This publication examines the distinct philosophical foundations of different statistical modes of parametric inference. Unlike many other texts that focus on methodology and applications, this book focuses on a rather unique combination of theoretical and foundational aspects that underlie the field of statistical inference. Readers gain a deeper understanding of the evolution and underlying logic of each mode as well as each mode's strengths and weaknesses. The book begins with fascinating highlights from the history of statistical inference. Readers are given historical examples of statistical reasoning used to address practical problems that arose throughout the centuries. Next, the book goes on to scrutinize four major modes of statistical inference: * Frequentist * Likelihood * Fiducial * Bayesian The author provides readers with specific examples and counterexamples of situations and datasets where the modes yield both similar and dissimilar results, including a violation of the likelihood principle in which Bayesian and likelihood methods differ from frequentist methods. Each example is followed by a detailed discussion of why the results may have varied from one mode to another, helping the reader to gain a greater understanding of each mode and how it works. Moreover, the author provides considerable mathematical detail on certain points to highlight key aspects of theoretical development. The author's writing style and use of examples make the text clear and engaging. This book is fundamental reading for graduate-level students in statistics as well as anyone with an interest in the foundations of statistics and the principles underlying statistical inference, including students in mathematics and the philosophy of science. Readers with a background in theoretical statistics will find the text both accessible and absorbing.

Longitudinal Data Analysis

Author : Jason Newsom
ISBN : 9781136705472
Genre : Psychology
File Size : 70. 93 MB
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First Published in 2012. Routledge is an imprint of Taylor & Francis, an informa company.

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